Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

New paper offers new insights into role carcinoma-associated fibroblasts play in tumor biology

A new paper by a team of researchers led by Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology in the Department of Biological Sciences at the University of Notre Dame, offers important new insights into the role carcinoma-associated fibroblasts (CAFs) play in tumor biology.

9 May 2014

Patients with Parkinson's disease show improvements after exenatide therapy

Follow-Up Study Published in the Journal of Parkinson's Disease Supports an Earlier "Proof of Concept" Trial. A follow-up study of patients with Parkinson's disease (PD) who participated in an earlier "proof of concept" clinical trial using exenatide showed that improvements persisted twelve months after discontinuing exenatide therapy.

9 May 2014

Two young neuroscientists win CAN Young Investigator Awards for 2014

The Canadian Association for Neuroscience is proud to announce that Dr. Stephanie Borgland, from the Hotchkiss Brain Institute at University of Calgary, and Dr. Brian Chen, from the Centre for Research in Neuroscience at McGill University, are both winners of CAN Young Investigator Awards for 2014.

8 May 2014

Phillips-Medisize enters into definitive agreement with Golden Gate Capital

Phillips-Medisize Corporation today announced that it has entered into a definitive agreement under which Golden Gate Capital will acquire the Company from funds managed by Kohlberg & Company, L.L.C.

7 May 2014

New research focuses on using wheat fiber to lower cholesterol and prevent development of heart disease

The saying, "we are what we eat," has never been more true. Nutritionists increasingly emphasize that the nutrients in the foods we consume can potentially create health and reduce disease.

7 May 2014

Snacking linked with abdominal fat and fatty liver

Researchers from The Netherlands found that snacking on high-fat and high-sugar foods was independently associated with abdominal fat and fatty liver (hepatic steatosis).

7 May 2014

Isis Pharmaceuticals reports pro forma net operating loss of $22.6 million for Q1 2014

Isis Pharmaceuticals, Inc. today reported a pro forma net operating loss (NOL) of $22.6 million for the three months ended March 31, 2014 compared to pro forma operating income of $4.5 million for the same period in 2013.

6 May 2014

Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Novartis today presented results from a pivotal Phase III trial of investigational therapy Signifor® LAR (pasireotide LAR; SOM230) in patients with acromegaly for whom current standard of care provides inadequate disease control.

6 May 2014

Factors that lead to diabetes contribute to low milk supply in some new mothers

New studies provide fresh evidence that the same factors that lead to diabetes contribute to low milk supply in some new mothers.

6 May 2014

Women with elevated levels of liver enzyme prior to pregnancy twice as likely to develop gestational diabetes

Women with high levels of a common liver enzyme measured prior to pregnancy were twice as likely to subsequently develop gestational diabetes than those with the lowest levels, according to a Kaiser Permanente study published today in the journal Diabetes Care.

5 May 2014

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Isis Pharmaceuticals, Inc. announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS.

2 May 2014

Highly stressed people who eat lot of high-fat are more prone to health risks

New research out of UC San Francisco is the first to demonstrate that highly stressed people who eat a lot of high-fat, high-sugar food are more prone to health risks than low-stress people who eat the same amount of unhealthy food.

30 Apr 2014

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Danone Institute International announced today that prominent scientist Gokhan S. Hotamisligil, MD, PhD, is the recipient of the 9th Danone International Prize for Nutrition for his outstanding research in immunology and metabolic diseases.

30 Apr 2014

Controlling glucose in the blood may decrease individuals' diabetes risk over time

In healthy individuals, the amount of glucose, or sugar, in the blood increases after eating. When glucose increases, levels of insulin increase to carry the glucose to the rest of the body. Previous research has shown that extreme increases in glucose and insulin in the blood can lead to poor glucose control and increase an individual's risk of developing diabetes over time. Now, a University of Missouri researcher has found that when women consumed high-protein breakfasts, they maintained better glucose and insulin control than they did with lower-protein or no-protein meals.

29 Apr 2014

Report focuses on behavioral issues linked with patients' self-management of type 2 diabetes

Clinical Therapeutics features a special report in its April issue focusing primarily on the behavioral issues associated with patients' self-management of type 2 diabetes.

29 Apr 2014

Study: Genetics as well as environment in womb play important roles in development of baby

A recent study led by A*STAR's Singapore Institute for Clinical Sciences (SICS) found that genetics as well as the environment in the womb play important roles in the development of the baby.

29 Apr 2014

Severe diabetes linked to brain atrophy

Type 2 diabetes may be associated with brain degeneration, according to a new multicenter study published online in the journal Radiology. The study also found that, contrary to common clinical belief, diabetes may not be directly associated with small vessel ischemic disease, where the brain does not receive enough oxygenated blood.

29 Apr 2014

Research to understand how low blood sugars cause irregular heartbeats in diabetes

Dangerous overnight blood sugar levels often go undetected and cause prolonged periods of heart rhythm disturbances in older patients with Type 2 diabetes and associated heart problems, new research reveals.

29 Apr 2014

Young onset age heightens Type 2 diabetes complication risks

Patients who develop Type 2 diabetes before the age of 40 years have higher complication risks at any given age than those who develop it later in life, research shows.

28 Apr 2014

Monarch Medical Technologies gets FDA clearance for new glucose management solution

Monarch Medical Technologies, the pioneer and leader in mitigating risk associated with drugs and processes of concern in hospitalized patients, today announced the U.S. Food and Drug Administration clearance of its new glucose management solution, EndoTool IV.

28 Apr 2014

Insulin News and Research

Further Reading

New paper offers new insights into role carcinoma-associated fibroblasts play in tumor biology

Patients with Parkinson's disease show improvements after exenatide therapy

Two young neuroscientists win CAN Young Investigator Awards for 2014

Phillips-Medisize enters into definitive agreement with Golden Gate Capital

New research focuses on using wheat fiber to lower cholesterol and prevent development of heart disease

Snacking linked with abdominal fat and fatty liver

Isis Pharmaceuticals reports pro forma net operating loss of $22.6 million for Q1 2014

Novartis presents Phase III results of Signifor LAR therapy in patients with acromegaly

Factors that lead to diabetes contribute to low milk supply in some new mothers

Women with elevated levels of liver enzyme prior to pregnancy twice as likely to develop gestational diabetes

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Highly stressed people who eat lot of high-fat are more prone to health risks

Gokhan S. Hotamisligil named recipient of the 9th Danone International Prize for Nutrition

Controlling glucose in the blood may decrease individuals' diabetes risk over time

Report focuses on behavioral issues linked with patients' self-management of type 2 diabetes

Study: Genetics as well as environment in womb play important roles in development of baby

Severe diabetes linked to brain atrophy

Research to understand how low blood sugars cause irregular heartbeats in diabetes

Young onset age heightens Type 2 diabetes complication risks

Monarch Medical Technologies gets FDA clearance for new glucose management solution

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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