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Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

People with better physical fitness are less likely to develop Alzheimer's disease

People who are more physically fit are less likely to develop Alzheimer's disease than people who are less physically fit, according to a preliminary study released today, February 27, 2022, that will be presented at the American Academy of Neurology's 74th Annual Meeting being held in person in Seattle, April 2 to 7, 2022 and virtually, April 24 to 26, 2022.

28 Feb 2022

New analysis highlights the changes in U.S. health care workforce during COVID-19 pandemic

A new analysis from Indiana University, the nonprofit Rand Corp. and the University of Michigan highlights the changes in the U.S. health care workforce during the COVID-19 pandemic and found that the average wages for U.S. health care workers rose less than wages in other industries during 2020 and the first six months of 2021.

25 Feb 2022

Researchers study EEG patterns in dying man to understand brain activity at the end of life

Researchers describe their observations from continuous EEG recordings obtained from the brain of a dying 87-year-old man who was experiencing a heart attack after a traumatic subdural hematoma.

25 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

Researchers analyze the use of palliative care for hospitalized patients with both AKI and COVID-19

Acute kidney injury (AKI) is a common complication of COVID-19 and is associated with a higher risk of death. A new study published in CJASN has examined the use of palliative care in patients with COVID-19 and AKI.

24 Feb 2022

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Insilico Medicine, an end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that it has dosed multiple healthy volunteers in Phase I clinical trial evaluating ISM001-055, the first anti-fibrotic small molecule inhibitor generated by Insilico's AI-powered drug discovery platform for idiopathic pulmonary fibrosis (IPF).

24 Feb 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Watch: Seniors share how they’ve made it through the pandemic

Too often the voices of older people are not heard. Judith Graham, KHN’s Navigating Aging columnist, invited nine seniors from across the country to talk candidly about their highs and lows as they enter Year 3 of the pandemic, with lives reordered by risk and restriction.

24 Feb 2022

Abdominal obesity may lead to greater risk of COPD and asthma in women

Obesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by body mass index (BMI) and waist circumference, may result in a greater risk of chronic obstructive pulmonary disease (COPD) and asthma.

23 Feb 2022

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis.

23 Feb 2022

Large study funded by $33.1 million grant focuses on risk and resilience in the aging brain

A large study that investigates just what keeps our brains sharp as we age and what contributes to cognitive decline has been launched by researchers from Washington University School of Medicine in St. Louis, Harvard University/Massachusetts General Hospital, the University of Minnesota Medical School and the University of California Los Angeles.

23 Feb 2022

Daily activities linked to lower risk of heart disease in older women

Seniors take note, running or brisk walking is not the only way to reduce the risk of heart disease. Simply being "up and about" performing routine activities, referred to as daily life movement, including housework, gardening, cooking and self-care activities like showering can significantly benefit cardiovascular health.

22 Feb 2022

Aging News and Research

Novel molecular pathway shared by two neurodegenerative disorders discovered

Novel mechanism that connects circadian rhythm and muscle repair discovered

People with better physical fitness are less likely to develop Alzheimer's disease

New analysis highlights the changes in U.S. health care workforce during COVID-19 pandemic

Researchers study EEG patterns in dying man to understand brain activity at the end of life

Research could pave the way for adoption of precision medicine approaches for COVID-19

Researchers analyze the use of palliative care for hospitalized patients with both AKI and COVID-19

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Watch: Seniors share how they’ve made it through the pandemic

Abdominal obesity may lead to greater risk of COPD and asthma in women

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Large study funded by $33.1 million grant focuses on risk and resilience in the aging brain

Daily activities linked to lower risk of heart disease in older women

As covid slogs on, seniors find fortitude waning and malaise growing

New Olympus Discovery Center opens to advance human disease research

New insights into why women develop Alzheimer's symptoms earlier and exhibit faster memory decline

Risk factors for COVID-19 in older adult patients with cancer

Study reveals high prevalence of female pattern hair loss in postmenopausal women

Intergenerational violence exposure affects the age of menopause

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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