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CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Chinese scientists report high-resolution crystal structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

13 Apr 2020

Exercise enhances muscle-repair capabilities in old mice, Stanford study shows

A nightly jaunt on the exercise wheel enhances muscle-repair capabilities in old mice, according to a new study by researchers at Stanford School of Medicine.

13 Apr 2020

New technique for imaging proteins in 3D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.

13 Apr 2020

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

UTSW researchers uncover shape of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening genetic conditions called congenital myasthenic syndromes.

12 Apr 2020

Hinge Therapeutics and TUT collaborate to advance drug discovery by ion imaging

Hinge Therapeutics is an early-stage biopharmaceutical company focused on developing small-molecule therapeutics against traditionally undruggable/challenging targets for unmet medical needs.

9 Apr 2020

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

A new study published in the European Respiratory Journal in April 2020 reveals that people with smoking-damaged lungs and those with chronic obstructive pulmonary disease (COPD) are likely to have a higher level of the angiotensin-converting enzyme II (ACE2).

9 Apr 2020

Structural protein may be new target for diagnosis, treatment of depression

Scientists have zeroed in on a structural protein as a new target for the diagnosis and treatment of depression, according to research recently published in JNeurosci.

9 Apr 2020

Newer drug associated with significantly reduced rates of pulmonary complications

The tragic COVID-19 pandemic is creating new awareness regarding the importance of breathing problems, pneumonia and ventilators.

8 Apr 2020

Advance in understanding actin sheds light on cell function

Scientists have discovered more about actin, a chemical modification on one of the most abundant and important proteins.

8 Apr 2020

Chemists urged to have a practical input to fight against COVID-19

Diamond Light Source (Diamond) has been contributing heavily to the global effort to understand and combat COVID-19.

8 Apr 2020

Researchers gain new insight into how lipids function within tears

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.

7 Apr 2020

Researchers develop a unique radiochemical synthesis approach for treating cancer

Radiolabeled molecules, so-called radiotracers, help nuclear physicians to detect and precisely target tumors, which are often developing due to pathological changes in metabolic processes.

7 Apr 2020

Bedroom air filters provide asthma relief for children

A new study by American and Chinese scientists, published in the journal JAMA Pediatrics, in April 2020, shows that a simple bedroom filter can help asthmatic children breathe better.

6 Apr 2020

Discovery of novel brain-digestive link

Scientists across the globe have long studied the link between the brain and the digestive system. Previous studies have tied brain networks and how they influence the gastrointestinal tract or vice versa. Food has a unique effect on humans as food tastes or flavors often dictate food-seeking behaviors. So is the palate the only thing that controls food choices among humans?

6 Apr 2020

Research suggests an avenue to treat, prevent genetic disorders in the womb

New research led by hearing scientists at Oregon Health & Science University suggests an avenue to treat and prevent intractable genetic disorders before birth.

6 Apr 2020

Using marine natural product to inhibit cervical cancer

A sponge found in Manado Bay, Indonesia, makes a molecule called manzamine A, which stops the growth of cervical cancer cells, according to a recent publication in the Journal of Natural Products submitted by researchers at the Medical University of South Carolina and their collaborators.

6 Apr 2020

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.

5 Apr 2020

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's.

3 Apr 2020