Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Highly inflammatory rheumatoid arthritis patients more susceptible to cognitive impairment

Researchers assessed cognitive function among rheumatoid arthritis patients with ongoing inflammatory activity.

1 Aug 2024

Novel anti-tuberculosis compound targets bacterial membrane protein

Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Duisburg-Essen (UDE) have together succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. In the scientific journal Cell Chemical Biology, they describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.

1 Aug 2024

Scientists capture NMDAR protein's 'twist' motion, key to brain signaling

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These bindings control NMDAR's dance steps. When their routine is over, the NMDAR opens. This open ion channel generates electrical signals critical for cognitive functions like memory.

1 Aug 2024

AI unlocks potential of antimicrobial peptides for new antibiotics

In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers at The University of Texas at Austin have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.

1 Aug 2024

Hamster sera study reveals Omicron subvariants' vast antigenic diversity

Study developed an antigenic map of SARS-CoV-2 variants using hamster sera, revealing substantial antigenic variation among Omicron subvariants and highlighting their distinct immune escape capabilities.

1 Aug 2024

FDA clears UAB startup's TIX100 for clinical trials

The University of Alabama at Birmingham startup TIXiMED, Inc., has obtained clearance from the United States Food and Drug Administration to proceed to clinical trials under an Investigational New Drug for TIX100, its novel oral Type 1 diabetes drug.

31 Jul 2024

Study reveals serotonin's role in ependymoma tumor growth

Do neurons play a role in brain tumor growth and development? Scientists at St. Jude Children's Research Hospital and Baylor College of Medicine have evidence showing that, for childhood ependymomas, they do.

31 Jul 2024

Powerful visualization technologies offer new insight into understanding muscle contraction in humans

The connections between the nervous system and muscles develop differently across the kingdom of life.

31 Jul 2024

Research uncovers mechanism behind diaphragm weakness during mechanical ventilation in ICU patients

Researchers from Amsterdam UMC have found a new mechanism explaining diaphragm weakness that arises during mechanical ventilation in the intensive care unit. The diaphragm is the most important breathing muscle.

31 Jul 2024

Propofol shows potential for treating epilepsy and neurological disorders

The general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders, according to a study led by researchers at Weill Cornell Medicine and Linköping University in Sweden.

31 Jul 2024

New discovery unveils key process in DNA repair pathway

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer treatments in the future.

31 Jul 2024

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins.

31 Jul 2024

Spear Bio secures $45 million in oversubscribed Series A financing to accelerate product launch for protein research and disease diagnostics

WOBURN, Mass.–(BUSINESS WIRE)–Spear Bio Inc., a biotechnology company enabling the measurement of protein molecules down to dozens of copies with ubiquitous qPCR equipment, announced the successful closing of its $45 million Series A financing.

From Spear Bio 31 Jul 2024