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Discovering new natural products from human microbiomes

The idea of using microorganisms as a source of new active ingredients is not new. Numerous drugs have already been developed on the basis of natural products from bacteria and fungi.

17 Oct 2024

UF Health scientists receive major grant to combat antibiotic-resistant bacteria

University of Florida Health scientists exploring how combinations of antibiotics can fight resistant bacteria have been awarded an $11.8 million grant for work that could help save the tens of thousands of lives lost yearly to infections that are increasingly plaguing humanity.

17 Oct 2024

Rising concerns over benzodiazepine prescriptions in older stroke survivors

Although there has been a slight downward trend in the prescription of benzodiazepines (depressants that relieve anxiety, muscle spasms, produce sedation and reduce seizures) among older adults over the last decade, the rate of first-time prescriptions for these medications after an ischemic (clot-caused) stroke is still sizable, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

17 Oct 2024

Patients are relying on Lyft, Uber to travel far distances to medical care

When Lyft driver Tramaine Carr transports seniors and sick patients to hospitals in Atlanta, she feels like both a friend and a social worker.

17 Oct 2024

Older adults distrust AI for health information

While the vast majority of people over 50 look for health information on the internet, a new poll shows 74% would have very little or no trust in such information if it were generated by artificial intelligence.

17 Oct 2024

Pediatric brain tumor research takes leap forward with CBTN data

The Gabriella Miller Kids First Data Resource Center (Kids First DRC) announces the addition of the full Children's Brain Tumor Network (CBTN) dataset to the Kids First DRC portal. This significant milestone provides researchers worldwide with unprecedented access to a vast repository of pediatric brain tumor data, paving the way for groundbreaking discoveries and accelerating the development of innovative treatments.

17 Oct 2024

Assessing and addressing IP staffing needs in a pediatric setting

A new paper published today in the American Journal of Infection Control (AJIC) describes efforts at a major children's hospital to assess and fulfill its staffing needs for infection prevention and control, highlighting the challenges of allocating sufficient resources to this important role.

17 Oct 2024

Study shows safety of kidney transplants among those with HIV infections

It is just as safe and effective for people with HIV in need of kidney transplantation to get their organ from donors who are also HIV positive as it is from donors who are not infected with the virus, a new study shows.

16 Oct 2024

Adenine base editors show potential to correct X-CGD-causing mutations

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder characterized by high susceptibility to infections.

16 Oct 2024

UCLA and Parker Institute renew alliance to advance cancer immunotherapy

UCLA and the Parker Institute for Cancer Immunotherapy (PICI) have renewed their alliance to advance research in cancer immunotherapy and accelerate the development of curative treatments for the most difficult-to-treat cancers.

16 Oct 2024

New registry offers insights into quality of life for adults with congenital heart disease

For the first time, adults living with congenital heart disease (CHD) now have valuable insights into their long-term quality of life through data from the Congenital Heart Initiative (CHI).

16 Oct 2024

Major donation fuels advances in ophthalmic artificial intelligence

The Icahn School of Medicine has announced a $5 million gift from the John and Daria Barry Foundation for the Center for Ophthalmic Artificial Intelligence (AI) and Human Health.

16 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

Young adults face rising risk of large vessel occlusion strokes

New research published in the Journal of Stroke and Cerebrovascular Diseases confirms that strokes thought to happen in older adults are possible in the younger (defined as 18-50 years old) population.

16 Oct 2024

New blood test rapidly diagnoses heart attacks

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

16 Oct 2024

Genetic risk factors for long-COVID uncovered in a large multi-ethnic study

Researchers identified genetic loci and phenotypes linked to long-COVID in the largest multi-ethnic GWAS, revealing increased risk factors for chronic conditions like fatigue, depression, and fibromyalgia.

16 Oct 2024

Distinct immune profiles linked to adverse reactions from immunotherapy

Distinct immune "signatures" in patients who develop adverse events while taking immunotherapy for cancer may help oncologists identify patients at risk and treat them early to prevent serious side effects, suggests a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

15 Oct 2024

Genetic insights transform treatment for children with developmental disorders

Thousands of children with severe developmental disorders have benefited from more targeted treatments and support with genetic insights from the large-scale Deciphering Developmental Disorders (DDD) study, finds a new study.

15 Oct 2024

Revolutionizing AI training by emulating physician education

When human radiologists examine scans, they peer through the lens of decades of training. Extending from college to medical school to residency, the road that concludes in a physician interpreting, say, an X-ray, includes thousands upon thousands of hours of education, both academic and practical, from studying for licensing exams to spending years as a resident.

15 Oct 2024

COVID-19 raises the risk of type 2 diabetes in children, study reveals

Researchers found that children who contracted COVID-19 were at a higher risk of developing type 2 diabetes within six months, compared to those with other respiratory infections.

15 Oct 2024