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Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Omicron variant of SARS-CoV-2 leads to less severe disease in mouse models

Georgia State University researchers have found that the Alpha, Beta and Delta variants of SARS-CoV-2 were substantially more fatal in mouse models than the original strain of the virus that causes COVID-19.

27 Jun 2022

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

Scientists conducted a meta-analysis to study the impacts of COVID-19 on the male reproductive system.

27 Jun 2022

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

Researchers constructed a full-length SARS-CoV-2 spike structure in its membrane-bound state to study functionally relevant aspects of its global conformational dynamics.

27 Jun 2022

The prevalence of long-COVID in children and adolescents

A recent study published in the Scientific Reports journal assessed the incidence of long-coronavirus disease (COVID) among adolescents and children.

27 Jun 2022

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Scientists have described the development of a modified A549 cell line that shows a robust expression of ACE2 and TMPRSS2 and high susceptibility to SARS-CoV-2 infection.

24 Jun 2022

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

The original SARS-CoV-2 viral strain that emerged in early 2020 was able to latch on to sugars known as sialic acids, found on the surface of human cells, an ability that later strains did not retain.

24 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

The effect of the COVID-19 BNT162b2 vaccine on semen parameters among semen donors

Researchers explored the impact of COVID-19 BNT162b2 (Pfizer) vaccinations on male fertility among semen donors in Israel.

21 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

The impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant

Researchers assessed the impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant.

21 Jun 2022

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

A team of scientists from China has recently deciphered the structural basis of comparatively higher binding affinity of two Omicron sub-variants, namely B.1.1 and B.2, for human angiotensin-converting enzyme 2 (ACE2).

17 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

SARS-CoV-2 damages cilia

Researchers determine whether the interaction between ORF10 and ZYG11B promotes the dissemination of SARS-CoV-2.

15 Jun 2022

Scientists characterize type I IFN response during SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, Canadian researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on interferon (IFN) response.

15 Jun 2022

The virucidal effects of tea tree oil against FCoVII and HCoV-OC43

Researchers assessed the probable efficacy of tea tree oil (TTO) as a natural disinfectant against SARS-CoV-2 using the human coronavirus OC43 (HCoV-OC43) and feline coronavirus (FCoVII) as surrogate models.

14 Jun 2022

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

Researchers assessed the interactions between SARS-CoV-2 and ACE2.

14 Jun 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

ACE2 News and Research

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Omicron variant of SARS-CoV-2 leads to less severe disease in mouse models

Scientists conduct meta-analysis of the impact of SARS-CoV-2 on sperm parameters

A full model of the SARS-CoV-2 spike protein for studying its atomic-level dynamics by multiple microsecond simulations

The prevalence of long-COVID in children and adolescents

Scientists develop suitable human cell line for anti-SARS-CoV-2 drug screening

Scientists discover mechanism behind zoonotic transfer of SARS-CoV-2 virus

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

SARS-CoV-2 evades natural killer cell cytotoxic responses

The effect of the COVID-19 BNT162b2 vaccine on semen parameters among semen donors

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

The impact of epistatic interactions on the ACE2 affinity in the SARS-CoV-2 Omicron variant

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

Effectiveness of a hybrid vaccine against COVID-19 and influenza

SARS-CoV-2 damages cilia

Scientists characterize type I IFN response during SARS-CoV-2 infection

The virucidal effects of tea tree oil against FCoVII and HCoV-OC43

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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