Adolescents News and Research

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Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

18 Aug 2025

Detecting diabetes risk by analyzing household data

New research to be presented at the 2025 Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (September 15-19, 2025) shows that early detection of individuals at risk for diabetes is possible by analyzing the electronic records of people living within the same household for risk factors. The study is led by Dr Tainayah Thomas, Stanford University, Palo Alto, CA, USA, and colleagues.

18 Aug 2025

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

Adolescents who undergo bariatric surgery face a higher risk of weight regain, which can undermine treatment success and long-term health, if they have elevated blood levels of per- and polyfluoroalkyl substances (PFAS) prior to the procedure, according to new USC research.

14 Aug 2025

Pandemic left measurable changes in teen brains, hormones, and immunity

Adolescents assessed after COVID-19 lockdowns showed lower daily cortisol, higher inflammation, and reduced prefrontal cortex activity compared to matched pre-pandemic peers, suggesting widespread stress-related biological changes. These alterations mirror patterns seen after prolonged early-life stress, raising concerns about long-term health risks.

13 Aug 2025

Understanding opioid safety and overdose prevention for older adults

With increasing age, older adults are more likely to encounter health conditions and injuries that require opioid therapy for pain relief.

13 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Global review highlights gaps in adolescent mental health research

A new systematic review of 172 studies including data from over 12 million adolescents across 166 countries reveals that while cross-national adolescent mental health research including low- and middle-income countries has expanded significantly, large gaps remain in global representation.

12 Aug 2025

Research finds long-term health challenges in survivors of childhood cancer

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, today published a new study which found that some survivors of childhood cancer are more at risk for serious health issues as they grow older, including new cancers and chronic conditions like heart disease.

11 Aug 2025

Fifteen-year study shows major gains in diabetes technology use and patient outcomes

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found big increases in the use of continuous glucose monitoring and insulin delivery devices by children and adults with type 1 diabetes over a 15-year period, with corresponding jumps in optimal blood-sugar control.

11 Aug 2025

New insights into how keto diet can restore cognitive function following status epilepticus

Epilepsy affects over 70 million people worldwide, and a significant portion of patients suffer from drug-resistant epilepsy (DRE), where standard medications fail.

11 Aug 2025

Understanding the multifactorial causes of spina bifida

Spina bifida is among the most common and debilitating neural tube defects, affecting approximately 1 in every 2,875 newborns in the United States.

11 Aug 2025

Using machine learning framework to identify prognostic biomarkers in neuroblastoma

Neuroblastoma is the most common solid tumor in infants and accounts for nearly 15% of all pediatric cancer-related deaths.

11 Aug 2025

Childhood and adolescent immunizations decline in Michigan, study shows

Routine childhood and adolescent immunizations declined in Michigan between 2017 and 2023, particularly among counties with lower household income and higher uninsurance rates, a new study suggests.

11 Aug 2025

Study reveals an intergenerational link between parents' and their children's school commuting habits

If you used physically active modes of commuting to school, your children are likely to do the same. A study by the University of Jyväskylä, Finland, reveals an intergenerational link between parents' and their children's school commuting habits.

10 Aug 2025

How too much screen time affects kids’ heart health and what can reduce the risk

A large Danish cohort study found that higher screen time in childhood and adolescence is linked to worse cardiometabolic health, with shorter sleep amplifying the risk. Blood metabolomics revealed a signature of high screen time, and in teens, it was tied to higher predicted cardiovascular disease risk.

7 Aug 2025

Adolescents show lower rates of nonmedical ADHD drug use

Despite concerns about increased stimulant prescribing, nonmedical use of ADHD drugs among adolescents has declined in the last 20 years, a University of Michigan study shows.

6 Aug 2025

Excessive screen time linked to higher cardiometabolic risk in youth

Children and young adults who spend excessive hours glued to screens and electronic devices may have higher risks for cardiometabolic diseases, such as high blood pressure, high cholesterol and insulin resistance, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

6 Aug 2025

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

Sleep apnea, or difficulty breathing at night, is common among children with Down syndrome-affecting up to 80% compared to just 5% of the general pediatric population.

5 Aug 2025

Flu virus triggers neuropsychiatric symptoms not the medication

For decades, medical professionals debated whether a common antiviral medication used to treat flu in children caused neuropsychiatric events or if the infection itself was the culprit.

4 Aug 2025

Adolescents News and Research

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Detecting diabetes risk by analyzing household data

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

Pandemic left measurable changes in teen brains, hormones, and immunity

Understanding opioid safety and overdose prevention for older adults

Researchers find CFI deficiency alarmingly high in old order Amish

Global review highlights gaps in adolescent mental health research

Research finds long-term health challenges in survivors of childhood cancer

Fifteen-year study shows major gains in diabetes technology use and patient outcomes

New insights into how keto diet can restore cognitive function following status epilepticus

Understanding the multifactorial causes of spina bifida

Using machine learning framework to identify prognostic biomarkers in neuroblastoma

Childhood and adolescent immunizations decline in Michigan, study shows

Study reveals an intergenerational link between parents' and their children's school commuting habits

How too much screen time affects kids’ heart health and what can reduce the risk

Adolescents show lower rates of nonmedical ADHD drug use

Excessive screen time linked to higher cardiometabolic risk in youth

Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome

Flu virus triggers neuropsychiatric symptoms not the medication

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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