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Methylene blue emerges as an adjunct in septic shock

Recent evidence suggests methylene blue may help reduce vasopressor needs and ICU stays in septic shock, but current data do not support replacing standard therapies. Further research is needed to clarify its optimal dosing, timing, and patient selection for best outcomes.

26 Jun 2025

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.

26 Jun 2025

Prenatal exposure to nitrates associated with increased risk of preterm birth

Even low levels of nitrate-a common agricultural runoff and drinking water contaminant-are associated with increased risks of preterm birth and low birthweight babies, according to a new study published June 25 in PLOS Water by Jason Semprini of Des Moines University College of Health Sciences, US.

25 Jun 2025

Plant-based diets may help prevent erectile dysfunction

A narrative review in The Journal of Nutrition suggests that whole-food plant diets may help prevent or improve erectile dysfunction (ED) by supporting vascular health and reducing risk factors such as LDL cholesterol and inflammation. However, most evidence is observational, and more clinical trials are needed.

25 Jun 2025

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

A recent study published in Engineering has shed light on a novel combination therapy for rheumatoid arthritis (RA) that significantly reduces bone destruction by targeting the m6A methylation pathway.

24 Jun 2025

Experimental drug promotes weight loss by heating fat instead of suppressing appetite

An article published in the journal Nature Metabolism presents an experimental drug that stimulates adipose tissue cells to produce heat through a process known as thermogenesis, thereby promoting weight loss.

24 Jun 2025

Cannabidiol may help reduce problematic behaviors in autistic boys

Researchers at the Center for Medicinal Cannabis Research at University of California San Diego School of Medicine have found that cannabidiol (CBD), a non-intoxicating compound found in cannabis, could help reduce problematic behaviors in autistic boys.

23 Jun 2025

Researchers turn a deadly fungus into potent cancer-fighting compound

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells.

23 Jun 2025

Chinese scientists develop highly efficient process for beta-blocker production

Chinese scientists have developed a breakthrough process that significantly improves the efficiency and environmental friendliness of beta-blocker production-with a focus on the widely used compound propranolol, which plays a vital role in managing cardiovascular conditions such as hypertension, arrhythmia, and angina.

20 Jun 2025

Rapamycin offers life-extending benefits comparable to eating less

The anti-aging drug Rapamycin has the same life-extending effect as eating less, according to new research from the University of East Anglia and University of Glasgow.

19 Jun 2025

Genes may determine how early life exposures shape the gut microbiome

Early nutritional and antibiotic exposures affect adult gut microbiota, with genetic background and parent-of-origin significantly influencing outcomes.

19 Jun 2025

New insights into how inhalational anesthetics induce general anesthesia

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations.

18 Jun 2025

Compound-level diet analysis sheds light on hidden triggers in IBD

Dutch researchers identified specific food compounds that influence remission and flare risk in patients with inflammatory bowel disease. The study shows compound-level dietary analysis could help personalize IBD management and clarify conflicting advice about diet.

18 Jun 2025

Mycotoxin exposure during pregnancy linked to lower birthweight

Exposure to mycotoxins – a broad group of harmful substances produced by mold – during pregnancy may impact placental function, which could result in lower birthweight in humans, according to Rutgers Health researchers.

16 Jun 2025

Paper-based devices show high accuracy in detecting asymptomatic malaria

Devices made with cheap strips of paper have outperformed two other testing methods in detecting malaria infection in asymptomatic people in Ghana – a diagnostic advance that could accelerate efforts to eliminate the disease, researchers say.

16 Jun 2025

Single-dose of psilocybin shows long-term relief for depression in cancer patients

New results from a clinical trial reveal that a single dose of psilocybin-a naturally occurring psychedelic compound found in mushrooms-can provide sustained reductions in depression and anxiety in individuals with cancer suffering from major depressive disorder.

16 Jun 2025