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Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Modifying gene expression may provide path to preventive treatments for heart failure, study suggests

Heart failure refers to a condition in which heart muscle becomes weakened over time, making it increasingly difficult for the heart to pump blood through the body like it should.

4 Aug 2017

Drinking non-dairy alternatives linked to shorter childhood height

Choosing dairy milk may make a difference when it comes to your child's growth, according to a new study from the American Journal of Clinical Nutrition. Researchers found drinking non-dairy alternatives was associated with shorter childhood height compared to those who drank milk, among 5,000 Canadian children.

4 Aug 2017

Protein that protects fetus during pregnancy could help treat atopic dermatitis

A protein which protects the fetus during pregnancy, HLA-G1, shows high potential for treating atopic dermatitis and other related diseases.

4 Aug 2017

Study finding provides new target besides the brain to develop therapies for sleep disorders

Scientists exploring the brain for answers to certain sleep disorders may have been looking in the wrong place.

4 Aug 2017

Protein-rich diet may foster more tolerant, less inflammatory gut environment

Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don't sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues.

3 Aug 2017

Study findings could lead to more effective and faster acting antidepressants

For people suffering from depression, a day without treatment can seem like a lifetime. A new study explains why the most commonly prescribed antidepressants can take as long as six weeks to have an effect. The findings could one day lead to more effective and faster acting drugs.

3 Aug 2017

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

Patients with multiple hereditary exostoses (MHE)--a rare disease that causes the growth of multiple benign bone tumors -- have limited treatment options.

3 Aug 2017

IDT introduces first Cas9 enzyme variant that greatly reduces off-target effects in CRISPR genome editing

Integrated DNA Technologies today announced the launch of the first Cas9 enzyme variant that extensively reduces off-target effects in CRISPR genome editing without compromising on-target activity.

3 Aug 2017

Researchers ferreting out patients most likely to become resistant to cancer treatment

According to the National Cancer Institute, the number of people beating a cancer diagnosis reached nearly 14.5 million in 2014 and is expected to rise to almost 19 million by 2024. Now, that's good news, but it doesn't mean that cancer researchers - in the lab or clinic - are resting on any laurels.

2 Aug 2017

Loss of dietary protein from food as carbon dioxide emissions fail to fall - warn researchers

According to researchers at the Harvard T.H. Chan School of Public Health, if the present rates of carbon dioxide emissions do not stop, people in around 18 countries worldwide may face a loss of around 5% of the protein they obtain from their diet by 2015. This is due to the reduction in the nutrient values of crops such as rice, wheat and other staples. This would put an additional 150 million people at risk of dietary protein deficiency. This is the first study that actually quantifies the actual dietary health risk posed by greenhouse gas emissions.

2 Aug 2017

Stowers researchers solve 3D structure of critical protein complex using microscopy techniques

Researchers at the Stowers Institute for Medical Research have solved the three-dimensional structure of a complex that is essential for the correct sorting of chromosomes into eggs and sperm during reproductive cell division or meiosis.

2 Aug 2017

Researchers identify new methods that could improve treatment for infectious diseases

Researchers have discovered new methods that could improve treatment for infectious diseases by enabling earlier detection of influenza outbreaks and curtailing inappropriate antibiotic usage. The findings were presented today at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego.

2 Aug 2017

Amyloid precursor protein associated with AD may also be linked to intelligence in children

Rare mutations in the amyloid precursor protein (APP) have previously been shown to be strongly associated with Alzheimer's disease (AD).

2 Aug 2017

Aging chimps show Alzheimer’s like brain changes – new research shows

In a study published yesterday in the journal Neurobiology of Aging, researchers have reported that aged chimpanzees may show similar if not identical brain changes as persons with early Alzheimer's disease. Chimpanzees are the closes linked animals with humans and these findings may help understand the mechanism of development of Alzheimer’s disease believe researchers.

2 Aug 2017

Latency reversing agent makes dormant HIV-infected cells vulnerable to clearance

The ability for HIV to hide in the body in a dormant state makes curing the 40 million people living with the virus a challenge. Researchers at the University of North Carolina at Chapel Hill have shown the drug Vorinostat reverses this latency, causing resting CD4 T-cells to express HIV.

1 Aug 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

Doctoral student works toward developing gluten-free children’s snack

Research to develop a gluten-free children's snack made of millet and quinoa has earned doctoral student Gabriela John Swamy the Gerber Endowment in Pediatric Nutrition Graduate Scholarship.

1 Aug 2017

Researchers streamline beta cell differentiation process to develop safer cell therapy for diabetes

More than 36 million people globally are affected by type 1 diabetes (T1D), a lifelong disorder where insulin producing cells are attacked and destroyed by the immune system resulting in deficient insulin production that requires daily blood glucose monitoring and administration of insulin.

1 Aug 2017

WPI researchers receive NIH grant to develop heart muscle patch using biopolymer microthreads

A research team at Worcester Polytechnic Institute has been awarded a $452,000 National Institutes of Health grant to bioengineer a patch to help cardiac muscle beat more strongly and efficiently after a heart attack.

31 Jul 2017

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G Protein News and Research

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Modifying gene expression may provide path to preventive treatments for heart failure, study suggests

Drinking non-dairy alternatives linked to shorter childhood height

Protein that protects fetus during pregnancy could help treat atopic dermatitis

Study finding provides new target besides the brain to develop therapies for sleep disorders

Protein-rich diet may foster more tolerant, less inflammatory gut environment

Study findings could lead to more effective and faster acting antidepressants

Scientists propose therapeutic strategy to suppress formation of hereditary bony tumors

IDT introduces first Cas9 enzyme variant that greatly reduces off-target effects in CRISPR genome editing

Researchers ferreting out patients most likely to become resistant to cancer treatment

Loss of dietary protein from food as carbon dioxide emissions fail to fall - warn researchers

Stowers researchers solve 3D structure of critical protein complex using microscopy techniques

Researchers identify new methods that could improve treatment for infectious diseases

Amyloid precursor protein associated with AD may also be linked to intelligence in children

Aging chimps show Alzheimer’s like brain changes – new research shows

Latency reversing agent makes dormant HIV-infected cells vulnerable to clearance

Expert highlights CRISPR’s applications, limitations, and ethical concerns

Doctoral student works toward developing gluten-free children’s snack

Researchers streamline beta cell differentiation process to develop safer cell therapy for diabetes

WPI researchers receive NIH grant to develop heart muscle patch using biopolymer microthreads

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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