Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Study investigates COVID-19 vaccination in pregnancy

A new study discusses the risk of COVID-19-related complications in pregnancy and the role of vaccination in reducing this risk.

17 May 2022

Researchers explore COVID-19 vaccination in immunocompromised individuals

A new study discusses the safety and efficacy of the COVID-19 vaccination and potential strategies to optimize protection in patients with impaired immunity.

17 May 2022

Broad-spectrum polymeric antivirals against SARS-CoV-2

In a recent study published in the journal Advanced Science, researchers evaluated the potential and applicability of macromolecular viral inhibitors against respiratory viral pathogens.

17 May 2022

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

A study conducted at the University of São Paulo's Medical School (FM-USP) in Brazil, with results reported in an article published in the journal Immunity & Ageing, shows that chronic obstructive pulmonary disease (COPD) leads to premature senescence (age-related impairment) of the immune system.

13 May 2022

Study investigates antibody-mediated response against different SARS-CoV-2 variants

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on antibody-mediated immunity.

10 May 2022

Deoxyribonucleic acid nanostructure sensor found to rapidly detect and inhibit SARS-CoV-2

Researchers reported on a three-layer designer deoxyribonucleic acid (DNA) nanostructure (DDN) strategy-based sensor designed by them for rapid and accurate SARS-CoV-2 detection and inhibition.

9 May 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

In a recent study published in Biomedicines, researchers explored the utility of natural killer (NK) cells in coronavirus disease 2019 (COVID-19).

28 Apr 2022

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Researchers assessed the epigenetic aging in COVID-19 patients and its impact on COVID-19 severity by a genome-wide deoxyribonucleic acid methylation profiling analysis.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Characteristics of viral infection super-spreaders

Researchers evaluated whether certain super-spreaders transmit viral infection better and the impacts of individual variance in epidemiological characteristics.

26 Apr 2022

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

In a recent study published in the journal Nature, the researchers investigated the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccine on memory B cells.

25 Apr 2022

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

Researchers at the University of Texas Medical Branch recently confirmed the presence of neutralizing antibodies to SARS--COV-2 in a common subcutaneous antibody therapy (Hizentra) used to treat immunocompromised or immunodeficient patients, citing its protective benefits to the immunocompromised patient community.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Continual genomic surveillance in Africa provides insights into evolving SARS-CoV-2 pandemic

Researchers described how SARS-CoV-2 genomic sequencing efforts in Africa helped identify two of the five SARS-CoV-2 VOCs, and their early analysis.

22 Apr 2022

Advancements in HIV science

As far as viruses go, human immunodeficiency virus (HIV) is quite simple. About 100,000 times smaller than a red blood cell, the virus expresses just a dozen proteins, yet it can establish a lifelong infection that, if left untreated, causes acquired immunodeficiency syndrome (AIDS) and death.

20 Apr 2022

Fully vaccinated HIV patients may be less susceptible to develop severe breakthrough SARS-CoV-2 infection

A new study found that the risk of severe breakthrough infection of SARS-CoV-2 is low among fully vaccinated HIV patients.

19 Apr 2022

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Researchers investigated the longevity and intensity of the SARS-CoV-2 vaccine immune response in patients suffering from immune-mediated inflammatory diseases.

15 Apr 2022

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Researchers identified mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleoproteins (NP) epitope flanking regions and their potential effects on CD8+ T cell activation.

12 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

Immunodeficiency News and Research

Further Reading

Study investigates COVID-19 vaccination in pregnancy

Researchers explore COVID-19 vaccination in immunocompromised individuals

Broad-spectrum polymeric antivirals against SARS-CoV-2

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

Study investigates antibody-mediated response against different SARS-CoV-2 variants

Deoxyribonucleic acid nanostructure sensor found to rapidly detect and inhibit SARS-CoV-2

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Characteristics of viral infection super-spreaders

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

Common subcutaneous antibody therapy for immunodeficient patients has anti-SARS-CoV-2 antibodies

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Continual genomic surveillance in Africa provides insights into evolving SARS-CoV-2 pandemic

Advancements in HIV science

Fully vaccinated HIV patients may be less susceptible to develop severe breakthrough SARS-CoV-2 infection

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Immunocompromised hosts with Delta/Omicron co-infections

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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