Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Small increases in daily steps may slow Alzheimer’s progression

Increasing your steps by even a little bit may help slow down the progression of Alzheimer's disease among people at heightened risk, according to a new study.

3 Nov 2025

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Acute myeloid leukemia driven by tandem duplications within the UBTF gene (UBTF-TD AML) is a high-risk pediatric cancer in urgent need of novel therapeutic options.

3 Nov 2025

Genetic insights into vestibular system damage from ototoxic drugs

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

31 Oct 2025

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.

30 Oct 2025

Some hormonal contraceptives linked to higher risk of breast cancer

Some common hormonal contraceptives are linked to a slightly higher risk of breast cancer than others.

30 Oct 2025

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

Enhancing ALS diagnosis with dual blood biomarkers

Despite modern imaging and genetic testing, diagnosing amyotrophic lateral sclerosis (ALS) remains challenging, particularly when distinguishing it from clinically similar neurodegenerative disorders.

29 Oct 2025

New genetic marker may improve the ability to predict life-threatening reactions to gout medication

A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.

29 Oct 2025

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

29 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus can redistribute throughout the body.

28 Oct 2025

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

A new research paper documents the outcomes of five volunteers who continued to receive 40Hz light and sound stimulation for around two years after participating in an MIT early-stage clinical study of the potential Alzheimer's disease therapy.

27 Oct 2025

How many headers are too many before football crosses the safety line?

A systematic review in the British Journal of Sports Medicine finds major inconsistencies in how heading impacts are measured, urging the use of wearable technology and standardized metrics to safeguard players from potential long-term brain injury.

23 Oct 2025

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

23 Oct 2025

AI tool detects intestinal parasites in stool samples more accurately than traditional methods

Scientists at ARUP Laboratories have developed an artificial intelligence (AI) tool that detects intestinal parasites in stool samples more quickly and accurately than traditional methods, potentially transforming how labs diagnose parasitic infections around the world.

23 Oct 2025

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

23 Oct 2025

New gene-editing method can correct many disease-causing mutations in mammalian cells

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

23 Oct 2025

AI-driven eye screening aims to close the diabetic vision gap in community clinics

A new trial will evaluate whether integrating autonomous AI screening for diabetic retinopathy into U.S. federally qualified health centers can boost screening completion and accelerate early detection. The DRES-POCAI protocol tests a real-world, point-of-care model that links FDA-cleared AI with electronic health records to close gaps in diabetes eye care.

22 Oct 2025

Pathology News and Research

Further Reading

Small increases in daily steps may slow Alzheimer’s progression

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Genetic insights into vestibular system damage from ototoxic drugs

Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

Study finds more commonalities between CTE and Alzheimer's disease at the genetic level

Some hormonal contraceptives linked to higher risk of breast cancer

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Enhancing ALS diagnosis with dual blood biomarkers

New genetic marker may improve the ability to predict life-threatening reactions to gout medication

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Daily 40Hz audiovisual stimulation may slow cognitive decline in late-onset Alzheimer's patients

How many headers are too many before football crosses the safety line?

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

AI tool detects intestinal parasites in stool samples more accurately than traditional methods

Disruption of glial circadian rhythms linked to Alzheimer's disease progression

New gene-editing method can correct many disease-causing mutations in mammalian cells

AI-driven eye screening aims to close the diabetic vision gap in community clinics

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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