Efficacy News and Research

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How effective is tecovirimat as a treatment against monkeypox?

A new study evaluated the use of tecovirimat for monkeypox treatment during the current outbreak.

9 Aug 2022

Combination of interventions more effective at reducing children’s symptoms of depression and anxiety

Behavioral scientists have long researched how to help children cope with extreme adversity – such as poverty or exposure to violence. Yanping Jiang, a researcher at the Rutgers Institute for Health, thinks she's found the answer in rural China.

9 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

Powerful injectable gel provides hope for preventing glioblastoma relapse

Like the hardiest weed, glioblastoma almost always springs back - usually within months after a patient's initial brain tumor is surgically removed.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Should pregnant women be included clinical trials?

The current study reports some of the scientific, ethical, and legal considerations that will support the inclusion of pregnant women in future research.

8 Aug 2022

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

In the initial NADIM trial, neoadjuvant chemoimmunotherapy was shown to be highly effective in patients with resectable stage IIIA non-small cell lung cancer.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

College nutrition course increases healthier eating among students

Fast food and away-from-home meal consumption is associated with increasing obesity in adults; often an unhealthy dietary behavior established in the critical time frame of young adulthood.

8 Aug 2022

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

A recent paper describes the use of aprotinin, a protease inhibitor that works across several pathways, to reduce the severity of COVID-19.

8 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Efficacy News and Research

How effective is tecovirimat as a treatment against monkeypox?

Combination of interventions more effective at reducing children’s symptoms of depression and anxiety

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

Powerful injectable gel provides hope for preventing glioblastoma relapse

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Should pregnant women be included clinical trials?

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

College nutrition course increases healthier eating among students

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

New method can modify an entire substance class of medically relevant natural products

What does the future look like for TB care?

Study identifies broad-spectrum antibody that neutralizes SARS-CoV-2 variants of concern

Scientists develop a novel, highly-efficient sample preparation method for single-cell proteomics

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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