Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Armetheon plans to develop tecarfarin against prosthetic heart valves or chronic renal dysfunction

Armetheon, Inc., a clinical stage biopharmaceutical company, announced today that it plans to develop its novel oral anti-coagulant (OAC), tecarfarin (ATI-5923), for a patient population which includes those who have prosthetic heart valves or chronic renal dysfunction.

11 Mar 2013

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Treatment with intravenous low-molecular-weight iron dextran seems to be an effective alternative for patients with nondialysis chronic kidney disease who remain anemic despite receiving oral iron and erythropoiesis-stimulating agents.

8 Mar 2013

Failure to use aspirin before angioplasty increases death rate

Despite recommendations from leading medical groups, a surprising number of patients are not given aspirin before artery-clearing coronary angioplasty and stenting, and those patients have a significantly higher in-hospital death rate, according to research from a Michigan network being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Telemedicine use appears to help urban communities achieve blood pressure goals

Using a telemedicine system to engage people in underserved, urban communities to measure and report their blood pressure remotely-outside of the doctor's office-appears to help them achieve blood pressure goals and improve adherence to lifestyle changes and medication recommendations, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Even minor weight loss is associated with worse health outcomes among patients implanted with a certain type of defibrillator known as cardiac resynchronization therapy with defibrillator (CRT-D), according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Nearly 90% of young children continue to struggle with ADHD symptoms despite treatment

A study published in the March 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that 9 out of 10 young children with moderate to severe attention-deficit/hyperactivity disorder (ADHD) continue to experience serious to severe symptoms and impairment long after their original diagnoses, and in many cases, despite treatment.

8 Mar 2013

Boosting hypocretin could elevate both mood and alertness in humans

What makes us happy? Family? Money? Love? How about a peptide? The neurochemical changes underlying human emotions and social behavior are largely unknown. Now though, for the first time in humans, scientists at UCLA have measured the release of a specific peptide, a neurotransmitter called hypocretin, that greatly increased when subjects were happy but decreased when they were sad.

8 Mar 2013

Technique breathes new life into gastric cancer diagnosis

A nanomaterial breath test can accurately distinguish gastric cancer from benign stomach disorders, preliminary results show.

7 Mar 2013

Study reveals increased dietary salt intake may lead to autoimmune disorders

Increased dietary salt intake can induce a group of aggressive immune cells that are involved in triggering and sustaining autoimmune diseases.

7 Mar 2013

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Kidney failure affects 25 million individuals in the U.S. and many more throughout the world. Loss of kidney function means the majority of these patients must undergo dialysis treatments to remove excess fluids and waste products. Although dialysis therapy coupled with medication has improved the life expectancy for people with kidney failure, for unknown reasons, patients' risk of sudden heart failure and death remains 10 to 20 times greater than average.

7 Mar 2013

High HDL levels block development of aneurysms in the aorta

New research provides early evidence that 'good' cholesterol may possess anti-aneurysm forming properties. In laboratory-based investigations, scientists found that increased levels of high-density lipoproteins (HDL), the so-called good cholesterol, blocked the development of aneurysms - dangerous 'ballooning' in the wall of a blood vessel - in the body's largest artery, the aorta.

7 Mar 2013

University of Sunderland pharmaceutical scientists receive CFUK grant for research into cystinosis

Pharmaceutical scientists at the University of Sunderland have been awarded £125,000 by the Cystinosis Foundation (CF) UK to fund the next stage of their research into a rare genetic disease.

7 Mar 2013

FDA accepts AMAG’s Feraheme sNDA for review

AMAG Pharmaceuticals, Inc. today announced that the United States Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use, which was submitted to the FDA in December 2012.

6 Mar 2013

Neuromonitoring predicts functional outcome after rectal cancer surgery

Intraoperative neuromonitoring of the bladder and internal anal sphincter can accurately predict postsurgical urinary and anorectal function, research suggests.

6 Mar 2013

UK’s health performance declining compared with 14 EU countries over past 20 years

Six decades of universal free health care, the introduction of widespread public health initiatives (eg, tobacco control, cancer screening, and immunisation), and substantial increases in health expenditure have failed to improve the UK’s health outcomes or longevity ranking against the average of 14 other original members of the European Union, Australia, Canada, Norway, and the USA (EU15+) over the past 20 years.

6 Mar 2013

Endocrine Society issues position statement on estradiol measurement

In a Position Statement unveiled today, The Endocrine Society advocates that all methods for measuring estrogens, which play a crucial role in human biology, be made traceable to a common standard.

6 Mar 2013

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Nikolai Begg grew up in a box of LEGO- bricks and hasn't stopped tinkering since. Today he is an accomplished inventor with a portfolio of novel medical devices. Begg is the recipient of the prestigious $30,000 Lemelson-MIT Student Prize for his inventions that are making surgical procedures less invasive.

6 Mar 2013

Sanford Health announces new limb preservation program

Sanford Health announces a new limb preservation program, Sanford Limb Preservation Center. The center specializes in treating lower extremity wounds in patients at high risk of amputation and compromised leg and toe function, particularly those with diabetes and peripheral arterial disease.

5 Mar 2013

People with variations in FTO gene could be at increased risk of melanoma

The research shows that people with particular variations in a stretch of DNA within the FTO gene, called intron 8, could be at greater risk of developing melanoma.

5 Mar 2013

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Interim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).

5 Mar 2013

Nephrology News and Research

Further Reading

Armetheon plans to develop tecarfarin against prosthetic heart valves or chronic renal dysfunction

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Failure to use aspirin before angioplasty increases death rate

Telemedicine use appears to help urban communities achieve blood pressure goals

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Nearly 90% of young children continue to struggle with ADHD symptoms despite treatment

Boosting hypocretin could elevate both mood and alertness in humans

Technique breathes new life into gastric cancer diagnosis

Study reveals increased dietary salt intake may lead to autoimmune disorders

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

High HDL levels block development of aneurysms in the aorta

University of Sunderland pharmaceutical scientists receive CFUK grant for research into cystinosis

FDA accepts AMAG’s Feraheme sNDA for review

Neuromonitoring predicts functional outcome after rectal cancer surgery

UK’s health performance declining compared with 14 EU countries over past 20 years

Endocrine Society issues position statement on estradiol measurement

Inventors from 3 leading universities receive $30,000 Lemelson-MIT Student Prize

Sanford Health announces new limb preservation program

People with variations in FTO gene could be at increased risk of melanoma

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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