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Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells.

18 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Bacterial infections can lead to the formation of abscesses - pockets of dead cells and debris surrounded by inflammatory immune cells. Bacteria multiply within abscesses, causing more inflammation and further damage to surrounding tissues.

17 Jan 2024

Study: Breast cancer deaths continue to drop as treatments improve

Deaths from breast cancer dropped 58% between 1975 and 2019 due to a combination of screening mammography and improvements in treatment, according to a new multicenter study led by Stanford Medicine clinicians and biomedical data scientists.

17 Jan 2024

Study highlights a potential new strategy to target triple-negative breast cancer

Cleveland Clinic researchers have successfully developed a therapeutic peptide that blocks aggressive cancer cells from multiplying rapidly.

17 Jan 2024

Men with enlarged breast tissue may be at greater risk of early death

Men with enlarged breast tissue, not caused by excess weight—a condition formally known as gynecomastia—may be at heightened risk of an early death before the age of 75, suggests the first study of its kind, published online in the open access journal BMJ Open.

17 Jan 2024

New, automated shake and fire platforms from Copley cut the burden of MDI and nasal drug product testing.

The latest generation of Vertus® automated shake and fire platforms from Copley Scientific make it easy and intuitive to integrate automation into a wide range of drug product testing workflows to boost productivity, drive down test variability, and simplify training.

From Copley Scientific Limited 17 Jan 2024

Overcoming adherence challenges: Innovative patch enables controlled drug delivery

A breakthrough in transdermal drug delivery.

17 Jan 2024

What led to a decline in US breast cancer mortality between 1975 and 2019?

Breast cancer mortality rates among United States (US) women aged 30-79 years between 1975 and 2019.

17 Jan 2024

Unlocking the anti-inflammatory secrets of bergamot byproducts

The positive effect of bergamot derivatives.

17 Jan 2024

CGRP antagonists and dietary changes show promise for migraine treatment

Review in "Medicina" explores advancements in migraine therapy, highlighting the role of CGRP antagonists and dietary interventions like ketogenic and low-glycemic diets in reducing migraine frequency and severity.

17 Jan 2024

Phase 3 trial shows acoramidis safe and effective for transthyretin amyloid cardiomyopathy

Pumping over 100,000 times a day, the heart is a critical muscle needed to deliver oxygen and nutrients to our organs to sustain healthy bodily function.

16 Jan 2024

Spider venom molecule meets benchmarks to treat heart attack and stroke

A spider venom molecule being investigated by a University of Queensland team has met critical benchmarks towards becoming a treatment for heart attack and stroke.

16 Jan 2024

Conscience's open science competition yields hits for new Parkinson's drugs

As part of its pioneering approach to drug discovery, the Canadian nonprofit Conscience announced today that its first open science competition has resulted in the identification of seven promising molecules, or "hits," that show potential for new, more effective drugs for familial Parkinson's disease.

16 Jan 2024

Drugs News and Research

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Study: Breast cancer deaths continue to drop as treatments improve

Study highlights a potential new strategy to target triple-negative breast cancer

Men with enlarged breast tissue may be at greater risk of early death

New, automated shake and fire platforms from Copley cut the burden of MDI and nasal drug product testing.

Overcoming adherence challenges: Innovative patch enables controlled drug delivery

What led to a decline in US breast cancer mortality between 1975 and 2019?

Unlocking the anti-inflammatory secrets of bergamot byproducts

CGRP antagonists and dietary changes show promise for migraine treatment

Phase 3 trial shows acoramidis safe and effective for transthyretin amyloid cardiomyopathy

Spider venom molecule meets benchmarks to treat heart attack and stroke

Conscience's open science competition yields hits for new Parkinson's drugs

Vanderbilt launches $13 million trial to test repurposed drugs for Rett syndrome

Poverty may combine in a synergistic manner with chronic inflammation to reduce health, life expectancy

Breakthrough nano-shield blocks selective allergic reactions

What would a second Trump presidency look like for health care?

Migraine linked to increased risk of inflammatory bowel disease in new study

Study warns of increased risks in heart patients using ED drugs with nitrates

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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