Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

OPKO Health acquires Cytochroma

OPKO Health, Inc. announced that it has completed the acquisition of Cytochroma Inc. Cytochroma's lead products include CTAP101 Capsules, a vitamin D prohormone to treat secondary hyperparathyroidism (SHPT) in patients with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency, and Fermagate Tablets, a new and potent non-absorbed phosphate binder to treat hyperphosphatemia in CKD patients on chronic hemodialysis.

4 Mar 2013

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.

2 Mar 2013

No increased risk for inflammatory bowel disease with isotretinoin

Researchers report no link between isotretinoin use for the treatment of acne and increased risk for inflammatory bowel disease in women of reproductive age.

1 Mar 2013

Urinary cystatin C prognostic marker in acute kidney injury

Urinary cystatin C level may be a useful biomarker for discriminating between prerenal and intrinsic acute kidney injury, report researchers.

1 Mar 2013

Lung congestion increases dialysis patients' risks of premature death or heart attacks

Asymptomatic lung congestion increases dialysis patients' risks of dying prematurely or experiencing heart attacks or other cardiac events, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

1 Mar 2013

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants.

1 Mar 2013

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

Some patients are genetically prone to such dangerously high levels of cholesterol that no amount of diet, exercise and medications can reduce their cholesterol to safe levels.

1 Mar 2013

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Researchers at the University of Michigan School of Kinesiology have received a $1 million grant to study how exercise and other therapies might work differently in lean and obese individuals.

28 Feb 2013

Anti-LG3 associated with high rate of organ rejection during transplantation

A team led by Dr. Marie-Jos-e H-bert from the University of Montreal Hospital* Research Centre (CRCHUM) has discovered a new cause of organ rejection in some kidney transplant patients. Her team has identified a new class of antibodies - anti-LG3 - which when activated lead to severe rejection episodes associated with a high rate of organ loss.

28 Feb 2013

GLP-1 pancreatitis concerns justified

Study results have raised further concerns over a link between pancreatitis and the use of glucagon-like peptide-1 (GLP-1)-based therapies for patients with Type 2 diabetes.

28 Feb 2013

Study designs and tests 60 compounds for their ability to kill human cancer cells

Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.

28 Feb 2013

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

CellAegis Devices, Inc., announced today that it has received an Investigational Testing Approval from Health Canada that allows the initiation of clinical testing in Canada of the Company's autoRIC Device for Chronic Remote Ischemic Conditioning (CRIC).

27 Feb 2013

Complementary medicine risks: an interview with Dr Andrew Boyden, NPS MedicineWise

Complementary medicines include products containing herbs, vitamins, minerals, nutritional supplements, homoeopathic medicines, certain aromatherapy products and traditional Chinese medicines. For this reason they are also called herbal, natural or alternative medicines.

26 Feb 2013

Anemia medication recall could affect thousands of kidney-disease patients

The recall comes as a sharp blow to Affymax, a small biotechnology firm based in Palo Alto, Calif., that developed Omontys and has no other late-stage drugs in its pipeline.

26 Feb 2013

Xellia to develop new antibiotics effective against multi-drug resistant Gram-negative bacteria

Xellia Pharmaceuticals, a fully integrated specialty pharmaceutical company focusing on the global anti-infective market, announced today that it is developing new antibiotics effective against multi-drug resistant (MDR), Gram-negative bacteria.

26 Feb 2013

Henry Ford Hospital scientists to research into hypertension and tissue and organ damage

A senior staff scientist and his team at Henry Ford Hospital have been awarded a five-year, $12.4 million grant by the National Institutes of Health for their research into the damaging effects of high blood pressure on various organs in the body.

26 Feb 2013

Antioxidant boosts liver transplant outcomes

Infusion of N-acetylcysteine in liver donors can significantly improve the outcome of transplantation, research shows.

25 Feb 2013

Greek and Spanish patients can now read EAU Patient Information in their native language

Greek and Spanish-speaking patients with kidney or ureteral stones can now read EAU Patient Information in their native language. The Endourology, Laparoscopy and Urotechnology Section of the Hellenic Urologic Association (HUA) has provided the Greek translation and the Spanish translation is the result of a collaboration between the Spanish Association of Urology (AEU) and the Dominican Republic Society of Urology (SDU).

25 Feb 2013

Study shows how hyperparathyroidism affects people of different racial backgrounds

Unusually high calcium levels in the blood can almost always be traced to primary hyperparathyroidism, an undertreated, underreported condition that affects mainly women and the elderly, according to a new study by UCLA researchers.

22 Feb 2013

Combined complement mutations affect individuals' risk of aHUS and prognosis

Certain gene mutations affect individuals' risk of developing a serious kidney condition, as well as their prognosis after being diagnosed with the disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

22 Feb 2013

Nephrology News and Research

Further Reading

OPKO Health acquires Cytochroma

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

No increased risk for inflammatory bowel disease with isotretinoin

Urinary cystatin C prognostic marker in acute kidney injury

Lung congestion increases dialysis patients' risks of premature death or heart attacks

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Anti-LG3 associated with high rate of organ rejection during transplantation

GLP-1 pancreatitis concerns justified

Study designs and tests 60 compounds for their ability to kill human cancer cells

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

Complementary medicine risks: an interview with Dr Andrew Boyden, NPS MedicineWise

Anemia medication recall could affect thousands of kidney-disease patients

Xellia to develop new antibiotics effective against multi-drug resistant Gram-negative bacteria

Henry Ford Hospital scientists to research into hypertension and tissue and organ damage

Antioxidant boosts liver transplant outcomes

Greek and Spanish patients can now read EAU Patient Information in their native language

Study shows how hyperparathyroidism affects people of different racial backgrounds

Combined complement mutations affect individuals' risk of aHUS and prognosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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