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Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

A study in the Emerging Infectious Diseases journal shows treating 20% of COVID-19 patients with Paxlovid could save up to 0.85 million lives and reduce the economic burden by US $170.17 billion in the US.

14 Jan 2024

Study explores intratumoral microbiota as a novel frontier in cancer research

Researchers review the role of intratumoral microbiota in cancer development, suggesting its potential in predicting and treating various cancers.

14 Jan 2024

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

A new, systematic analysis of cancer cells identifies 370 candidate priority drug targets across 27 cancer types, including breast, lung and ovarian cancers.

13 Jan 2024

Planning prompts show promise in improving prescribing safety

Physicians who are notified that a patient has died of a drug overdose are more judicious in issuing controlled substances if the notification includes a plan for what to do during subsequent patient visits, according to a study published today in Nature Communications.

13 Jan 2024

New study offers hope for reducing malaria in pregnant women living with HIV

In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial funded by the European & Developing Countries Clinical Trials Partnership (EDCTP) and coordinated by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

12 Jan 2024

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

12 Jan 2024

A biological signature of desire helps explain the selective nature of pair bonds

Hop in the car to meet your lover for dinner and a flood of dopamine - the same hormone underlying cravings for sugar, nicotine and cocaine - likely infuses your brain's reward center, motivating you to brave the traffic to keep that unique bond alive.

12 Jan 2024

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

12 Jan 2024

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

12 Jan 2024

Trump official who OK’d drugs from Canada chairs company behind Florida’s import plan

The Food and Drug Administration's unprecedented approval of Florida's plan to import drugs from Canada was made possible only after Alex Azar, as the Trump administration's Health and Human Services secretary, certified that bringing medicines over the border could be done safely.

12 Jan 2024

Long-term expansion and self-organization of human fetal brain organoids

Researchers establish fetal brain organoids as a versatile platform for brain cancer modeling.

12 Jan 2024

Big data analysis paves way for personalized ovarian cancer treatment

A recent study led by Hidenori Machino at the RIKEN Center for Advanced Intelligence Project (AIP) and the National Cancer Center Research Institute in Japan used a big data multi-omics analysis to examine changes in gene expression as cells from human fallopian tubes become cancerous.

11 Jan 2024

Simple biomarkers offer early warning of hidden heart risk in childhood cancer survivors

Data from the St. Jude lifetime cohort study (St. Jude LIFE) revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors.

11 Jan 2024

UTEP researchers unveil promising new weapon against leukemia and lymphoma

Researchers at The University of Texas at El Paso have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of therapy.

11 Jan 2024

KFF Health News' 'What the Health?': All about the (government) funding

As this election year begins in earnest, making it harder for Congress to pass bills, lawmakers on Capitol Hill are still struggling to fund the government for the fiscal year that began last October.

11 Jan 2024

First organoid model of the human conjunctiva produced

The Organoid group at the Hubrecht Institute produced the first organoid model of the human conjunctiva. These

11 Jan 2024

Glioblastoma tumor cells mimic neurons to evade treatment

Certain cancers are more difficult to treat because they contain cells that are highly skilled at evading drugs or our immune systems by disguising themselves as healthy cells.

11 Jan 2024

American Heart Association's merit award recipients announced

The AHA celebrates 100 years of lifesaving work by announcing the recipients of its prestigious Merit Award.

11 Jan 2024

"Alkaline water" fails to be an effective alternative for prevention of recurrent urinary stones

Bottled water marketed as "alkaline water" is unlikely to be an effective alternative for prevention of recurrent urinary stones, reports a study in the January issue of The Journal of Urology, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

10 Jan 2024

Pangolins' genetic makeup linked to increased coronavirus susceptibility

Research reveals pangolins' vulnerability to coronavirus due to innate immune gene pseudogenization, impacting their antiviral response.

10 Jan 2024

Drugs News and Research

Paxlovid treatment in 20% of COVID-19 patients could avert 850,000 hospitalizations, save up to $170 billion

Study explores intratumoral microbiota as a novel frontier in cancer research

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

Planning prompts show promise in improving prescribing safety

New study offers hope for reducing malaria in pregnant women living with HIV

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

A biological signature of desire helps explain the selective nature of pair bonds

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Trump official who OK’d drugs from Canada chairs company behind Florida’s import plan

Long-term expansion and self-organization of human fetal brain organoids

Big data analysis paves way for personalized ovarian cancer treatment

Simple biomarkers offer early warning of hidden heart risk in childhood cancer survivors

UTEP researchers unveil promising new weapon against leukemia and lymphoma

KFF Health News' 'What the Health?': All about the (government) funding

First organoid model of the human conjunctiva produced

Glioblastoma tumor cells mimic neurons to evade treatment

American Heart Association's merit award recipients announced

"Alkaline water" fails to be an effective alternative for prevention of recurrent urinary stones

Pangolins' genetic makeup linked to increased coronavirus susceptibility

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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