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Scientists identifiy the way MDM2 protein can trigger the spread of cancer

The protein, MDM2, normally functions to control the activity of a key cancer preventing protein called p53.

25 Jul 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006

Basal tumours may originate from breast stem cells that have undergone genetic mishaps

Findings support previous speculation that breast stem cells, or very early descendents, are the cells from which basal tumours arise.

24 Jul 2006

Serotonin reciprocally regulates melanocortin neurons to modulate food intake

Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin.

24 Jul 2006

Increasing deaths from opioid analgesics in the United States

Trends analysis of drug poisoning deaths has helped explain a national epidemic of overdose deaths in the USA that began in the 1990s, concludes Leonard Paulozzi and colleagues at the Centers for Disease Control and Prevention.

24 Jul 2006

Genetic key to treating deadly fungal infections

University of Minnesota researchers have discovered how a prevalent fungal pathogen that causes 10,000 deaths per year in the United States overcomes the effects of antifungal drugs by duplicating a section of one of its chromosomes.

24 Jul 2006

Gleevec may cause heart problems

Gleevec, the wildly successful poster-child of a new generation of cancer drugs aimed at specific targets in the cancer cell, can be dangerous to the heart.

24 Jul 2006

Increasing deaths from opioid analgesics in the United States

24 Jul 2006

Digital magnetofluidics holds hope for better medicine

Critical advances in medicine and environmental protection promise to emerge from a new method for biochemical analysis of fluids developed by an international science team led in part by Arizona State University researchers.

21 Jul 2006

Long term ibuprofen therapy given after brain injury worsens cognitive abilities

Researchers at the University of Pennsylvania School of Medicine found that chronic ibuprofen therapy given after brain injury worsens cognitive abilities.

21 Jul 2006

Dangers of unregulated herbal therapy

A Case Report in this week's issue of The Lancet highlights the dangers of unregulated herbal therapy.

21 Jul 2006

Psychotherapeutic interventions for cannabis abuse

Marijuana dependence and abuse can be moderately improved by various psychotherapy treatments - but reduced use rather than abstinence may be the best clinicians can hope for at this time, a new review finds.

21 Jul 2006

New 'patch' drug therapy for Alzheimer's has fewer side effects

Alzheimer's, is the most common form of dementia and affects as many as 15 million people worldwide.

20 Jul 2006

Leukemia gene normally has mammary gland function

A gene critical for normal mammary gland function during nursing helps trigger highly lethal leukemias when it undergoes a mutation that fuses it to another gene, according to investigators at St. Jude Children's Research Hospital.

19 Jul 2006

Drugs given to stop nausea and vomiting after surgery help only a few people

Between 10 - 28% of people benefit from taking an anti-emetic drug to prevent nausea or vomiting after surgery - this means that if everyone was given the drug the majority of patients would be exposed to the risk of side-effects without gaining any benefit.

19 Jul 2006