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UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Microscopy in Neuroscience Research

An interview with ZEISS, to discuss the challenges faced in neuroscience research microscopy techniques and their latest microscope.

From ZEISS Microscopy GmbH 17 Feb 2020

New molecular 'fishing' technology can find individual molecules in blood

Like finding a needle in a haystack, Liviu Movileanu can find a single molecule in blood. Movileanu, professor at Syracuse University, and recently graduated Ph.D. student Avinash Thakur will present their research on Monday, February 17 at the 64th Annual Meeting of the Biophysical Society in San Diego, California.

16 Feb 2020

Novel formulation allows use of toxin from rattlesnake venom to control neuropathic pain

Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful muscle paralyzer than botulinum toxin.

16 Feb 2020

Novel technology could reduce coronavirus diagnostic time to 15 minutes

Diagnosing coronavirus takes approximately one hour using current methods. A new technology, based on a combination of optics and magnetic particles, can rapidly test 100 samples of patients potentially infected with the virus and reduce the diagnostic time to approximately 15 minutes.

16 Feb 2020

Promising molecule could stop or slow Parkinson’s

A promising molecule has offered hope for a new treatment that could stop or slow Parkinson’s, something no treatment can currently do.

14 Feb 2020

A simple, straightforward approach to protein modification

Proteins are essential parts of organisms; thus, they are widely used in medicine, biology and chemistry. Enhancing their inherent properties by adding functional molecules to their structures is a common and important step in many fields.

14 Feb 2020

Universal 'One-Size-Fits-All' Cancer Treatment

Andrew Sewell speaks to News-Medical about his breakthrough research, in which he has discovered a new T-Cell that could treat most cancers.

14 Feb 2020

Inflammation detected in the brains of veterans with Gulf War Illness

In a new discovery, researchers at Massachusetts General Hospital have detected widespread inflammation in the brains of veterans diagnosed with Gulf War Illness.

13 Feb 2020

Discovery of compound that reverses the fertility clock

The reproductive years of a woman are at their peak before the age of 30. Beyond that, fertility starts to decline, and by the age of 40, fertility potential is about half the level it was before 30 years old. Many women experience fertility issues, but now a new study on mice may help reverse the clock on eggs, offering new fertility hope to older women.

13 Feb 2020

New mathematical technique describes the behavior of cellular enzymes

Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell.

13 Feb 2020

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

A light-sensitive protein can restore mitochondria function in fruit flies bearing a gene mutation associated with Parkinson’s disease and relieve its symptoms, report researchers at Juntendo University in the journal Communications Biology.

13 Feb 2020

New insights may guide design of light-sensitive proteins with desired properties

A team of scientists from the Department of Energy's SLAC National Accelerator Laboratory and Stanford University has gained insight into how electric fields affect the way energy from light drives molecular motion and transformation in a protein commonly used in biological imaging.

13 Feb 2020

New approach for organic synthesis may apply to drug discovery

After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery

12 Feb 2020

UQ researchers reverse reproductive aging process in mice

Researchers have lifted fertility rates in older female mice with small doses of a metabolic compound that reverses the aging process in eggs, offering hope for some women struggling to conceive.

12 Feb 2020

Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

Rutgers engineers develop 'bio-ink' for 3D-printed materials

Rutgers biomedical engineers have developed a "bio-ink" for 3D printed materials that could serve as scaffolds for growing human tissues to repair or replace damaged ones in the body.

11 Feb 2020

Bats' fierce immune response to viruses could drive zoonotic emergence

It's no coincidence that some of the worst viral disease outbreaks in recent years -- SARS, MERS, Ebola, Marburg and likely the newly arrived 2019-nCoV virus -- originated in bats.

10 Feb 2020

First artificial enzyme with non-biological catalytic sites created

A new study published in the journal Nature Catalysis on February 10, 2020, reports the creation of a new artificial enzyme from two components, both non-biological in origin. This event marks the first such successful biological catalyst to contain a non-biological active site. The study shows that this type of synergistic combination of an amino acid not found in nature with a copper-based catalyst is capable of powerful catalytic action, unlike most other artificial enzymes.

10 Feb 2020