Immune System News and Research

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Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Researchers from the Duke Molecular Physiology Institute have been investigating genetic associations with more severe disease and examining the associations that certain genetic features have with other diseases.

13 Dec 2021

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

For patients with the blood cancer multiple myeloma, vaccination against COVID-19 provides some protection against coronavirus infection but to a far lower degree than the general population of cancer survivors, a new study by Dana-Farber Cancer Institute investigators shows.

13 Dec 2021

NCCN publishes new guidelines to help cervical cancer patients become more informed about care

The National Comprehensive Cancer Network has published new NCCN Guidelines for Patients: Cervical Cancer to help people with cervical cancer become more informed, suggest what conversations to have with their doctor, and be active decision makers in their treatment.

13 Dec 2021

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

A new study shows that the ACE2 and RBD of coronavirus spike fragments have different binding strengths and dissociation rates when they are glycosylated and non-glycosylated.

13 Dec 2021

NYU Langone Health performs second successful investigational xenotransplantation procedure

Less than two months after the first breakthrough surgery, NYU Langone Health has performed its second successful investigational xenotransplantation procedure using a genetically engineered pig kidney.

13 Dec 2021

Third dose of SARS-CoV-2 vaccine increases protection against omicron variant

A new study examines the variation in vaccine effectiveness against virus variants using estimated reductions in neutralizing antibody levels from published studies.

13 Dec 2021

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

A new mouse study found that intranasal administration of MV130 protected against severe acute respiratory syndrome coronavirus 2.

13 Dec 2021

Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

The emergence of COVID-19 variants such as delta and omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.

11 Dec 2021

UCLA research points the way towards a longer-lasting COVID vaccine

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.

11 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care investigated whether nivolumab has an added benefit over watchful waiting in the adjuvant treatment of adults with carcinoma of the esophagus or the gastroesophageal junction and pathological residual disease after prior neoadjuvant chemoradiotherapy (CRT).

10 Dec 2021

Impact of mRNA-1273 vaccination during early pregnancy

Researchers from Yale University School of Medicine found that vaccination during the first trimester does not produce congenital disabilities or size abnormalities.

10 Dec 2021

Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences.

9 Dec 2021

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

A University of Florida Health researcher has successfully analyzed the many mutations in the omicron variant of the SARS-CoV-2 virus, a crucial step in better understanding the variant's potential threat and ways to combat it.

9 Dec 2021

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

9 Dec 2021

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Potential association between senescence and aging in COVID-19

A review published in Cells discussed characteristics of cellular senescence and its potential role in COVID-19.

9 Dec 2021

Immune System News and Research

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

NCCN publishes new guidelines to help cervical cancer patients become more informed about care

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

NYU Langone Health performs second successful investigational xenotransplantation procedure

Third dose of SARS-CoV-2 vaccine increases protection against omicron variant

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

Genetic-code expansion technique to potentially create next-generation vaccine candidate

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

UCLA research points the way towards a longer-lasting COVID vaccine

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Indication of minor added benefit of nivolumab for adjuvant treatment of esophageal cancer

Impact of mRNA-1273 vaccination during early pregnancy

Insight into immune cell communication may pave the way for new cancer vaccines

Analysis finds substantially more mutations in the omicron SARS-CoV-2 variant

Investigational mRNA-based HIV vaccine shows promise in mice and non-human primates

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Potential association between senescence and aging in COVID-19

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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