Immune System News and Research

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Scientists identify compound that shows potential in easing the symptoms of coronavirus infections

By studying a disease caused by a close cousin of the virus behind COVID-19, a team of scientists has identified a compound that shows potential in easing the symptoms of coronavirus infections.

1 Nov 2021

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of platelet inhibitors could be associated with a reduction in the occurrence of digital ulcers, painful sores on the extremities that can progress to gangrene, in people with systemic sclerosis.

1 Nov 2021

Curious case of SARS-CoV-2 Delta variant in a dog

In a recent study, researchers document the detection and sequencing of an AY.3 virus from a 12-year-old Collie living with a SARS-CoV-2-infected owner.

1 Nov 2021

Evidence antibodies targeting HCoV-OC43 are robustly boosted in response to SARS-CoV-2 but not vaccination

The magnitude of cross-reactive antibodies correlated well with responses to the SARS-CoV-2 spike protein and the S2 subdomain.

1 Nov 2021

COVID-19 antibody levels stay more durable in vaccinated people with prior SARS-CoV-2 infection

In what is believed to be one of the largest studies of its kind, Johns Hopkins Medicine researchers have shown that antibody levels against SARS-CoV-2 (the COVID-19 virus) stay more durable — that is, remain higher over an extended period of time — in people who were infected by the virus and then received protection from two doses of messenger RNA (mRNA) vaccine compared with those who only got immunized.

1 Nov 2021

Neurological complications are higher with SARS-CoV-2 infection than COVID vaccine, study finds

Research published in the journal Nature Medicine suggests a risk for neurological complications after the first shot of a COVID-19 vaccine. However, the likelihood of developing neurological complications remains far greater among people infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

31 Oct 2021

Researchers explore whether salivary glands infected with SARS-CoV-2 can diminish long-term immunity

University of Utah Health scientists are leading an effort to determine if salivary glands infected with the virus that causes COVID-19 could diminish a person’s long-term immunity to the disease after being immunized or after recovering from the illness.

30 Oct 2021

Two new studies show how to enhance effectiveness of cancer immunotherapy

Two new studies revealed that anti-PD-1 immunotherapy given before surgery was safe and effective for patients with oral-cavity squamous cell carcinoma (OCSCC) and identified potential molecular biomarkers in the blood and tumors of patients that would show how likely it is that someone would respond to immunotherapy.

30 Oct 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

Scientists develop new approach to combat treatment-resistant melanoma

Researchers from the Centenary Institute have developed a new approach to fighting melanomas that fail to respond – or are resistant – to standard treatments. The deadliest form of skin cancer, melanoma is responsible for more than 1,700 deaths each year in Australia.

30 Oct 2021

New project investigates stem cell therapy as a potential treatment for glaucoma

Oregon Health & Science University is part of a national research project investigating stem cell therapy as a potential treatment for glaucoma, the world's second leading cause of blindness.

29 Oct 2021

Study discovers inflammatory mediator critically involved in bacterial pneumonia

Researchers at Karolinska Institutet in Sweden report that a recently discovered inflammatory mediator, interleukin-26, appears to have an important role in pneumonia and contribute to the killing of bacteria.

29 Oct 2021

UKHSA’s Green Book updated to allow flexibility in COVID-19 booster vaccines for vulnerable people

COVID-19 booster vaccines can now be given sooner than six months after their second dose to certain vulnerable people where this makes operational sense, as the UKHSA's Green Book has been updated.

29 Oct 2021

Study uncovers unknown effects of COVID-19 virus on the immune system

COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections.

28 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

Third dose of Covid-19 vaccine benefits dialysis patients

In some patients, the immune system responds poorly to the second vaccination dose. This changes with the third shot.

28 Oct 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

Researchers investigated the neutralizing antibody response that different mRNA vaccines induce in both previously convalescent and SARS-CoV-2 naïve individuals.

28 Oct 2021

New mechanisms for treating impregnable KRAS mutant cancers with statins

Third-generation cancer immunotherapy, a method of removing cancer using the body's immune system, has shown remarkable clinical benefits in recent years, giving hopes to many researchers and patients.

27 Oct 2021

Taking lessons in molecular therapeutics from earthworms to combat COVID

Scientists were interested in further investigating the defense mechanism of earthworms in an effort to discover therapeutic solutions against SARS-CoV-2.

27 Oct 2021

Immune System News and Research

Scientists identify compound that shows potential in easing the symptoms of coronavirus infections

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

Curious case of SARS-CoV-2 Delta variant in a dog

Evidence antibodies targeting HCoV-OC43 are robustly boosted in response to SARS-CoV-2 but not vaccination

COVID-19 antibody levels stay more durable in vaccinated people with prior SARS-CoV-2 infection

Neurological complications are higher with SARS-CoV-2 infection than COVID vaccine, study finds

Researchers explore whether salivary glands infected with SARS-CoV-2 can diminish long-term immunity

Two new studies show how to enhance effectiveness of cancer immunotherapy

Researchers decipher when and why T cells become non-responsive to immunotherapy

Scientists develop new approach to combat treatment-resistant melanoma

New project investigates stem cell therapy as a potential treatment for glaucoma

Study discovers inflammatory mediator critically involved in bacterial pneumonia

UKHSA’s Green Book updated to allow flexibility in COVID-19 booster vaccines for vulnerable people

Study uncovers unknown effects of COVID-19 virus on the immune system

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Third dose of Covid-19 vaccine benefits dialysis patients

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Study finds one mRNA vaccine dose after SARS-CoV-2 infection produces highest neutralizing antibody titers

New mechanisms for treating impregnable KRAS mutant cancers with statins

Taking lessons in molecular therapeutics from earthworms to combat COVID

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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