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New strategic collaboration to accelerate treatments for unmet medical needs in oncology

The University of Texas MD Anderson Cancer Center and Taiho Pharmaceutical Co., Ltd., today announced a three-year strategic collaboration to accelerate the development of treatments for significant unmet medical needs in oncology, including patients with brain metastases and those with cancers refractory to available therapies.

25 Sep 2020

TL1A and its receptor could reduce fibrosis and tissue remodeling in patients with severe lung disease

Your lungs and airways need to be stretchy, sort of like balloons. Take a big breath, and they'll open right up.

25 Sep 2020

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Individuals with severe forms of COVID-19 disease can present with compromised type I interferon (IFN) responses based on their genetics, according to results published in two papers today in the journal Science.

25 Sep 2020

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Nine months into the global pandemic, which has infected more than 32 million people, there is still no approved effective and safe drug or vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Sep 2020

Research sheds light on how membrane proteins could be influenced by lipid environments

The cell membrane, the wall-like boundary between the cell interior and its outside environment, is primarily made up of two kinds of biomolecules: lipids and proteins. Different

24 Sep 2020

HSS researchers use novel MRI technique to study Parsonage-Turner Syndrome

Researchers at Hospital for Special Surgery (HSS) have received a grant from the National Institutes of Health to use a novel MRI technique known as magnetic resonance neurography, or MRN, to study Parsonage-Turner Syndrome (PTS), a painful nerve disorder that leads to severe weakness.

24 Sep 2020

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

As scientists race to discover new and effective antiviral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many novel approaches are being utilized. Now, a new study published on the preprint bioRxiv in September 2020 reports on the discovery of a potentially beneficial enzyme blocker that could inhibit SARS-CoV-2 viral replication.

24 Sep 2020

New knowledge on cellular makeup and growth of teeth can expedite developments in regenerative dentistry

New knowledge on the cellular makeup and growth of teeth can expedite developments in regenerative dentistry - a biological therapy for damaged teeth - as well as the treatment of tooth sensitivity.

24 Sep 2020

Combination of alcohol and nicotine during pregnancy increases health risk in newborns

University of Houston researchers have found that during early pregnancy, the mix of alcohol and nicotine significantly alters the gene regulatory pathways of the developing fetus, which can lead to major deficiencies in brain development.

24 Sep 2020

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

A fourth Phase 3 clinical trial evaluating an investigational vaccine for coronavirus disease 2019 (COVID-19) has begun enrolling adult volunteers.

23 Sep 2020

OXGENE launches a scalable, plasmid-free manufacturing system for AAV

OXGENE™, a biotechnology company designing and developing scalable gene therapy technologies, has today announced the launch of its scalable, plasmid-free manufacturing system for AAV.

From OXGENE 23 Sep 2020

Acquisition of a natural mutation primes SARS-CoV-2 for neutralization by a cross-reactive antibody

A team of scientists from the United States reveals that the acquisition of a natural mutation makes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) susceptible to neutralization by a cross-reactive SARS-CoV antibody. The study is currently available on the bioRxiv* preprint server.

22 Sep 2020

Study examines opinions, experiences of clinical oncologists on Federal Right to Try law

A new study published in the Journal of the National Cancer Institute is the first to examine the opinions and experiences of clinical oncologists working at a major medical center on the Federal Right to Try (RTT) law.

22 Sep 2020

NIH expands clinical trials to evaluate convalescent plasma as a treatment for COVID-19

Two randomized, placebo-controlled clinical trials funded by the National Institutes of Health (NIH) are expanding enrollment to further evaluate convalescent plasma as a treatment for patients hospitalized with COVID-19.

22 Sep 2020

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

The widespread use of antiretroviral therapy to suppress the HIV virus has helped tens of millions of people with HIV live healthier, longer lives--but an unfortunate consequence of people living longer with HIV is an increased risk of cancer.

22 Sep 2020

Researchers discover a hormone that might help tackle malabsorption

Scientists at Cincinnati Children's used human intestinal organoids grown from stem cells to discover how our bodies control the absorption of nutrients from the food we eat.

22 Sep 2020

Inhibition of SARS-CoV-2 with antisense oligonucleotides

A part of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA is highly conserved. Researchers have used this as a target for designing antisense oligonucleotide gapmers to cleave the RNA and disrupt virus replication. Their research is published as a preprint on the online server bioRxiv in September 2020.

22 Sep 2020

New national research and training hub at UW-Madison could transform medicine

A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.

22 Sep 2020

Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%.

21 Sep 2020

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival.

21 Sep 2020

Therapeutics News and Research

New strategic collaboration to accelerate treatments for unmet medical needs in oncology

TL1A and its receptor could reduce fibrosis and tissue remodeling in patients with severe lung disease

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Research sheds light on how membrane proteins could be influenced by lipid environments

HSS researchers use novel MRI technique to study Parsonage-Turner Syndrome

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

New knowledge on cellular makeup and growth of teeth can expedite developments in regenerative dentistry

Combination of alcohol and nicotine during pregnancy increases health risk in newborns

Fourth Phase 3 clinical trial evaluating COVID-19 vaccine begins in the U.S.

OXGENE launches a scalable, plasmid-free manufacturing system for AAV

Acquisition of a natural mutation primes SARS-CoV-2 for neutralization by a cross-reactive antibody

Study examines opinions, experiences of clinical oncologists on Federal Right to Try law

NIH expands clinical trials to evaluate convalescent plasma as a treatment for COVID-19

Research consortium receives $111 million NCI grant to prevent, treat HIV-related cancers

Researchers discover a hormone that might help tackle malabsorption

Inhibition of SARS-CoV-2 with antisense oligonucleotides

New national research and training hub at UW-Madison could transform medicine

Researchers identify genetic markers linked to higher risk of capecitabine-induced hand-foot syndrome

Immunotherapy benefits patients with gastric and esophageal cancers, new data shows

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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