Clinical Trial News and Research

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Celastrol shows potential anti-SARS-CoV-2 activity

A new study published on the bioRxiv* preprint server focuses on the in-silico predictions to repurpose existing drug compounds, that may have the ability to reverse the SARS-CoV-2 gene expression induced in host cells.

23 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

FDA approves clinical trials to test the safety of cancer-detection technology

The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at Case Western Reserve University: a tumor-targeting contrast agent that accurately detects aggressive prostate cancer in a magnetic resonance imaging (MRI) scan.

22 Apr 2021

New Phase 3 trial of therapeutics begins enrolling severely ill hospitalized COVID-19 patients

A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure.

22 Apr 2021

NCCS starts clinical trial to examine the use of TCM in countering cancer-related symptoms

The National Cancer Centre Singapore has started a clinical trial to examine the use of Traditional Chinese Medicine in countering cancer-related symptoms or side effects of cancer treatment to improve cancer survivors' quality of life.

22 Apr 2021

Stem cell therapy can repair brain damage and improve memory function in mice

A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia, a new UCLA study finds.

21 Apr 2021

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Human clinical trials have begun on a new vaccine candidate that may protect against not only SARS-CoV-2, the virus that causes COVID-19, but against at least two of the variants emerging around the world.

21 Apr 2021

Researchers study ways to improve pediatric heart transplant outcomes

Scientific research teams in California and Texas have been awarded nearly $1.4 million in grants to study ways to improve pediatric heart transplant outcomes.

21 Apr 2021

NIH funds large Phase 3 clinical trial to test repurposed drugs for treating COVID-19 symptoms

Using an ACTIV master protocol, the trial will focus on potential interventions for mild-to-moderate illness.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Study evaluates stem cells' ability to prevent major cause of death in preterm infants

A phase 2 clinical trial whose results were released today in STEM CELLS Translational Medicine might point to a way to overcome bronchopulmonary dysplasia (BPD), a major cause of death in preterm infants.

20 Apr 2021

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

It's now easier than ever to take part in a study that includes treatment for anxiety in children with autism spectrum disorder (ASD) at the UC Davis MIND Institute's Autism Center of Excellence.

20 Apr 2021

Sinovac COVID-19 vaccine shows 50% effectiveness in a cohort of Brazilian healthcare workers

CoronaVac is a well-tolerated vaccine containing inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and it induced humoral responses in phase 1 and 2 studies. Analysis of a Brazilian phase 3 clinical trial that evaluated 12,607 participants showed that the vaccine had an efficacy of 50.39% 15 days after the 2nd dose.

19 Apr 2021

Researchers show how to evaluate waning efficacy of COVID-19 vaccines

Researchers in the United States have demonstrated how to estimate the potentially waning efficacy of vaccines designed to protect against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Apr 2021

Once-a-week injectable insulin therapy proves to be safe, effective in people with Type 2 diabetes

Treating people with Type 2 diabetes with a new once-a-week injectable insulin therapy proved to be safe and as effective as daily insulin injections, according to the results of two international clinical trials published online today in Diabetes Care.

19 Apr 2021

Gene therapy for common forms of congenital blindness shows promise to improve vision

A new gene therapy for one of the most common forms of congenital blindness was safe and improved patients' vision, according to initial data from a clinical trial led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

19 Apr 2021

Mirati to contribute $4 million grant to support SU2C research on KRAS mutant cancers

Stand Up To Cancer and Mirati Therapeutics Inc. - a late-stage targeted oncology company - today announced that Mirati will contribute a $4 million grant to SU2C to develop new approaches to treat patients with KRAS mutant cancers, as a part of the SU2C Catalyst program.

19 Apr 2021

The shock and reality of catching Covid after being vaccinated

Robin Hauser, a pediatrician in Tampa, Fla., got covid in February. What separates her from the vast majority of the tens of millions of other Americans who have come down with the virus is this: She got sick seven weeks after her second dose of the Pfizer-BioNTech vaccine.

17 Apr 2021

New and more effective treatment for Pompe disease

Rare diseases are sometimes the most difficult to treat because of a lack of research and fewer participants to study.

16 Apr 2021

Clinical Trial News and Research

Celastrol shows potential anti-SARS-CoV-2 activity

Clinical trial examines metabolic effects of natural compound NMN in people

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

FDA approves clinical trials to test the safety of cancer-detection technology

New Phase 3 trial of therapeutics begins enrolling severely ill hospitalized COVID-19 patients

NCCS starts clinical trial to examine the use of TCM in countering cancer-related symptoms

Stem cell therapy can repair brain damage and improve memory function in mice

Argonne's Advanced Photon Source guided the development of new COVID-19 vaccine now in trials

Researchers study ways to improve pediatric heart transplant outcomes

NIH funds large Phase 3 clinical trial to test repurposed drugs for treating COVID-19 symptoms

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Study evaluates stem cells' ability to prevent major cause of death in preterm infants

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

Sinovac COVID-19 vaccine shows 50% effectiveness in a cohort of Brazilian healthcare workers

Researchers show how to evaluate waning efficacy of COVID-19 vaccines

Once-a-week injectable insulin therapy proves to be safe, effective in people with Type 2 diabetes

Gene therapy for common forms of congenital blindness shows promise to improve vision

Mirati to contribute $4 million grant to support SU2C research on KRAS mutant cancers

The shock and reality of catching Covid after being vaccinated

New and more effective treatment for Pompe disease

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