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Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

Researchers assessed the impact of the BNT162b2 SARS-CoV-2 vaccine-induced memory T cells on the SARS-CoV-2 Omicron variant.

19 May 2022

In-depth characterization of the BA.2 versus BA.1 variant

In a recent study published in the journal Nature, researchers evaluated the pathogenicity and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 variant in hamsters and mice.

19 May 2022

How does diet affect COVID-19?

Scientists review the current research on how changes in diet can affect infection with SARS-CoV-2.

19 May 2022

New, minimally invasive biomarker-based strategy 90% successful in detecting esophageal cancer

In a small but rigorous pilot study, Johns Hopkins Medicine researchers have shown that a novel, minimally invasive biomarker-based strategy they developed was 90% successful in detecting esophageal squamous cell carcinoma (ESCC), the predominant subtype of esophageal cancer worldwide.

18 May 2022

Study identifies cancer biomarkers based on a type of genetic modification

Biomarkers are often used during the management of cancer to guide treatment decisions and predict patient outcomes. However, it is often difficult to identify appropriate biomarkers that can be consistently reproduced and are easily analyzed with limited patient specimens.

18 May 2022

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, and young adult patients with solid tumors.

18 May 2022

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

A research team at LKS Faculty of Medicine, The University of Hong Kong discovered that exosomes derived from γδ-T cells (γδ-T-Exos) synergised with radiotherapy can control nasopharyngeal carcinoma (NPC) by overcoming the radioresistance of NPC cancer stem cells (CSCs) and preserve their tumor-killing and T cell-promoting activities in the immunosuppressive NPC microenvironment.

18 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Researchers demonstrate link between high-fat diet, nitric oxide levels and cancer development

It has long been hypothesized that dietary habits can precede and even exacerbate the development of cancer.

17 May 2022

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. According to a new multicenter study led by MedUni Vienna and conducted in collaboration with researchers from the Czech Republic, Hungary, Slovenia, Sweden and the United States, SCLC can be divided into several subgroups in terms of clinical behavior.

17 May 2022

A study of SARS-CoV-2-mRNA booster vaccinations in immunocompromised patients

In a recent study published in the journal Frontiers in Immunology, researchers assessed the immune responses induced by vaccination with the messenger ribonucleic acid (mRNA)-1273 vaccine or the BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections among immunocompromised individuals.

17 May 2022

New imaging probe illuminates breast cancer cells to optimize tumor removal

Nearly 13 percent of women born in the U.S. today will develop breast cancer at some point during their lives.

16 May 2022

New drug inhibits growth of the most aggressive meningiomas

When a specific non-metastatic brain tumor — a meningioma — recurs after surgery and radiation treatment, a patient is normally out of options. No drugs are approved for these aggressive tumors, which occur in up to 20 percent of cases and can lead to patient disability or even death.

16 May 2022

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Immunotherapy has transformed treatment for patients with stage 4 metastatic esophageal and gastric cancers. In patients with these malignancies, immunotherapy has been shown to prolong survival when patients' tumors exhibit a high expression of an immune-related protein called PD-L1.

16 May 2022

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Researchers compared the immunogenicity of or and reactogenicity to the BNT162b2 vaccine in Japanese adults and elders.

16 May 2022

Robotic surgery reduces readmissions, benefits patients' overall recovery

A new study, published in JAMA, has found that robotic surgery reduces the chance of readmission by half (52 per cent), and revealed a "striking" four-fold (77 per cent) reduction in prevalence of blood clots (deep vein thrombus and pulmonary emboli) - a significant cause of health decline and morbidity - when compared to patients who had open surgery.

15 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Collectively moving malaria parasites form vortices that are largely determined by physical principles

The disease of malaria is triggered by single-celled parasites that accumulate in large groups in the salivary glands of mosquitoes before transmission to human beings.

13 May 2022

Study reveals serum proteomic signatures of long COVID patients

In a recent study posted to the bioRxiv*preprint server, researchers evaluated the serum proteomic signatures of long coronavirus disease (COVID) patients.

13 May 2022

Penn study finds low uptake of first mutation-targeted bladder cancer drug

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

12 May 2022

Tumor News and Research

Study explores polyfunctionality of BNT162b2 COVID-19 vaccine-induced memory T-cells

In-depth characterization of the BA.2 versus BA.1 variant

How does diet affect COVID-19?

New, minimally invasive biomarker-based strategy 90% successful in detecting esophageal cancer

Study identifies cancer biomarkers based on a type of genetic modification

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

Exosomes derived from γδ-T cells synergized with radiotherapy can control nasopharyngeal carcinoma

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Researchers demonstrate link between high-fat diet, nitric oxide levels and cancer development

Small cell lung cancer subtypes respond differently to chemotherapeutics and targeted drugs

A study of SARS-CoV-2-mRNA booster vaccinations in immunocompromised patients

New imaging probe illuminates breast cancer cells to optimize tumor removal

New drug inhibits growth of the most aggressive meningiomas

Immunotherapy combined with chemoradiation and surgery could help treat nonmetastatic gastroesophageal cancer

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Robotic surgery reduces readmissions, benefits patients' overall recovery

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Collectively moving malaria parasites form vortices that are largely determined by physical principles

Study reveals serum proteomic signatures of long COVID patients

Penn study finds low uptake of first mutation-targeted bladder cancer drug

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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