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Genetically engineered animals help in scientific research that may benefit children

The recent use of genetically modified mice and rats in combination with an animal model of obstructive nephropathy, a type of renal disease, has given researchers new insight in the development of kidney disease.

21 Sep 2005

Adult sickle cell drug hydroxyurea proves effective in young children

A drug used for the treatment of sickle cell anemia in adults has now been shown to cause significant improvements in very young children with the disorder.

20 Sep 2005

Suppression of FOXO1a gene might kill resistant alveolar rhabdomyosarcoma (ARMS) tumors

FOXO1a caused death of tumor cells in laboratory study by triggering expression of caspase-3, which blocks cell division and causes cells to undergo apoptosis, according to St. Jude.

20 Sep 2005

Blood test to measure hormone prolactin can help determine type of seizure

Using a blood test to measure the level of the hormone prolactin can help determine, in certain clinical settings, whether an epileptic seizure has occurred, according to a guideline developed by the American Academy of Neurology and published in the September 13, 2005 issue of Neurology.

20 Sep 2005

Research could improve clinical care, help educate women on premature birth

A March of Dimes expert panel has recommended a targeted research agenda designed improve the lives of thousands of babies by preventing premature birth. The agenda has been published in the American Journal of Obstetrics and Gynecology.

20 Sep 2005

PUMA protein offers critical insights for developing new anti-cancer drugs

The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital.

20 Sep 2005

People who take risks more satisfied with their lives

Tall people are more prepared to take risks than small people, women are more careful than men, and the willingness to take risks markedly decreases with age: these are the findings arrived at by researchers from the Institute for the Study of Labor (IZA), the University of Bonn and the German Institute for Economic Research (DIW) in Berlin.

19 Sep 2005

Millenium Development Goals fail to include the goal of improving the mental health of the poor

Because the Millenium Development Goals fail to include the goal of improving the mental health of the poor, the world may not reach many of the goals, say researchers in an analysis published by PLoS Medicine.

19 Sep 2005

Kids at risk of TV / videogame seizures

The Epilepsy Foundation today issued new recommendations for families on how to limit the risk of seizures triggered by flashing images and certain patterns on television, videogames, computers and other video screens.

19 Sep 2005

Stress and breast cancer link

High levels of daily stress appear to result in a lower risk of developing breast cancer for the first time, says a study in the British Medical Journal.

19 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

Making practical markets for vaccines

Two papers published on September 13 in PLoS Medicine raise concerns about whether world leaders are getting good advice on how best to fund the development and delivery of new vaccines.

19 Sep 2005

Does surgery induce angiogenesis in dormant breast cancer?

Analysis of breast-cancer relapse patterns from two independent databases provides indirect evidence for the theory that surgery to remove the primary tumor may initiate formation of a new blood supply (angiogenesis) in formerly dormant metastases, accounting for a pattern of early relapse in younger women.

12 Sep 2005

Retinoic acid combined with PIC, a synthetic immunity booster, significantly elevates the immune system response to a tetanus shot

These results show that a natural product of vitamin A can have an important role in regulating immunity and, when administered along with PIC, might be a potentially powerful nutritional-immunological assist in vaccination."

12 Sep 2005

Spread of bird flu to the United States is a "time bomb waiting to go off"

One of the government's top scientists said Monday that the spread of bird flu to the United States is a "time bomb waiting to go off" but that federal and industry efforts to produce a vaccine are progressing.

12 Sep 2005

Need for more outdoor play spaces so that children could have more choice over materials, locations and playmates

Young children may be missing out on 'pretend' games like pirates and spacemen due to the demands of the school curriculum, according to research funded by the Economic and Social Research Council (ESRC).

12 Sep 2005

Children who survive cancer face educational difficulties and social isolation

A new study finds children who survive cancer have about twice the rate of educational and social problems compared to children without a history of cancer.

12 Sep 2005

HOXA1 is a gene that's been looking for a disorder for a long time

Researchers at Children's Hospital Boston, who specialize in studying the genetics of rare eye-movement disorders, have found a rare genetic syndrome whose implications go far beyond the eye, raising intriguing questions about human cardiovascular and brain development.

12 Sep 2005

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America, according to the study done by investigators at St. Jude Children's Research Hospital.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005