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Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

St. Jude Children’s Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients.

1 Sep 2005

C. elegans worm provides clues to dealing with human disease

A step towards understanding cell mutations that cause a variety of human diseases, particularly in children -- including that which brings about premature aging and early death -- has been taken by researchers at the Hebrew University of Jerusalem Silberman Institute of Life Sciences and the John Hopkins University School of Medicine.

1 Sep 2005

Discovery of gene that may play a role in centronuclear myopathy

By studying the molecules that regulate the formation of muscle, researchers at UT Southwestern Medical Center have discovered a gene that may play a role in a rare muscular disease in humans.

31 Aug 2005

Charles Darwin was right and chimp gene map proves it

According to scientists who have mapped the complete chimp genome and compared it to the human gene map, there is little genetic difference between humans and chimps, but those differences count for a lot.

31 Aug 2005

13 million children now living in poverty in the U.S.

In newly released data it appears that poor families and children are being left behind as the benefits of a steadily growing economy fail to trickle down to their level.

31 Aug 2005

Hutchinson-Gilford progeria syndrome in children may be helped by cancer drugs

Children who suffer from a rare disease called progeria, which accelerates aging and often kills patients when they are in their teens, may possibly be helped by drugs being developed to treat cancer.

31 Aug 2005

Early life exposure to second-hand smoke can produce life-long respiratory problems

A new study finds early life exposure to second-hand smoke can produce life-long respiratory problems. The study of 35,000 adult non-smokers in Singapore found that those who lived with a smoker during childhood had more respiratory problems, including chronic cough.

30 Aug 2005

Carbohydrate known as OGT2378 inhibits tumor growth

A non-toxic chemical compound that prevents cancer cells from producing a critical membrane component has been shown to suppress tumor growth and tumor size in mice without unwanted side effects, according to researchers at the Children’s National Medical Center in Washington, D.C.

30 Aug 2005

Teenage boys in cars with mates, are far more reckless

A new study from the U.S. goes a long way to confirm what many parents already suspected, roads would be a lot safer if there were fewer teenage boys driving, especially with their mates as passengers.

30 Aug 2005

Step towards understanding cell mutations that cause a variety of human diseases

A step towards understanding cell mutations that cause a variety of human diseases, particularly in children - including that which brings about premature aging and early death - has been taken by researchers at the Hebrew University of Jerusalem Silberman Institute of Life Sciences and the John Hopkins University School of Medicine.

30 Aug 2005

Children who eat cereal are more alert

Research conducted by the Cardiff University School of Psychology has revealed children who eat cereal are more alert and have fewer memory and attention span difficulties than those who skip breakfast.

30 Aug 2005

Scientists help narrow the search for BRCA1 carriers

Cancer Research UK scientists have identified a new test which may help narrow the search for breast cancer patients likely to carry the faulty BRCA1 gene.

30 Aug 2005

Better management of asthma possible

Better management of asthma in the community is not only possible, but has the potential to reduce the impact of the disease on people’s lives, according to a report by the Australian Centre for Asthma Monitoring (ACAM) , a collaborating unit of the Australian Institute of Health and Welfare.

30 Aug 2005

Which herbs and dietary supplements can help children with nausea, constipation and similar gastrointestinal problems?

As more parents choose home remedies for their children's gastrointestinal complaints, the question arises, which ones really work?

30 Aug 2005

Top doctors in UK fear for teens with change in alcohol laws

Doctors in the UK are concerned that any relaxation in the alcohol laws will only serve to cause a rise in cirrhosis among young people.

30 Aug 2005

Blocking Hutchinson-Gilford progeria syndrome (HGPS) with anticancer drugs

A class of anticancer drugs currently being evaluated in phase 3 clinical trials may also be an effective treatment for Hutchinson-Gilford progeria syndrome (HGPS), a fatal genetic disorder that causes premature aging.

29 Aug 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

Three-dimensional molecular structure of a promising malaria-vaccine component

An international team of scientists that includes a researcher from the U.S. Department of Energy's Brookhaven National Laboratory has determined the three-dimensional molecular structure of a promising malaria-vaccine component.

29 Aug 2005

Drugs known as farnesyltransferase inhibitors (FTIs) may hold promise for premature aging disorder

In a surprising development, a research team led by the National Human Genome Research Institute (NHGRI), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging.

29 Aug 2005

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Research published by the University of Helsinki, Finland, indicates that cytostatic and radiation therapies administered before stem cell transplantation often damage children's permanent teeth.

29 Aug 2005