Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

New study shows how a kidney biopsy can be used to tailor treatment for lupus patients

The kidneys of patients living with systemic lupus erythematosus are often under assault, and not all those living with the disease will respond to standard treatment.

21 May 2019

Innovative transplantation technique helps find early signs of type 1 diabetes

By the time type 1 diabetes is diagnosed, most of the insulin-producing beta cells have already been destroyed.

15 May 2019

Increasing early beta-cell proliferation could halt development of type 1 diabetes

Many in-development cures for type 1 diabetes have understandably focused on tackling the autoimmune aspect of the disease before figuring out a way to replace the destroyed beta cells. But what if focusing on the beta cells first could prevent their destruction altogether?

7 May 2019

Finding potential treatments for autoimmune diseases

More than 50 million Americans are affected by an autoimmune disease, with women at an increased risk for developing one.

7 May 2019

CU Anschutz researchers identify new immunodeficiency disease

A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers at the University of Colorado Anschutz Medical Campus providing unique insights into cell biology.

6 May 2019

UAB receives $17 million grant to explore immune cells in inaccessible tissues of the human body

University of Alabama at Birmingham researchers will receive $17.8 million in federal funding to attack a key "knowledge gap" in human immunology -- how the B cells and antibody-secreting cells that reside in tissues and organs differ from those found in blood.

23 Apr 2019

Scientists identify rare, paradoxical response to antiretroviral therapy

Antiretroviral therapy is usually very effective at suppressing HIV in the body, allowing a person's immune system to recover by preventing the virus from destroying CD4+ T cells.

19 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

MUSC study provides evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Human immunodeficiency virus, or HIV, attacks the immune system, making affected individuals more susceptible to infections. When patients with HIV are treated with antiretroviral therapy, their immune system can recover, but some of them produce self-destructive proteins, or autoantibodies.

2 Apr 2019

Pitt study sheds light on how immune cells help tumors to escape body's defenses

New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer Center sheds light on how tumors use the body's regulators of immunity for their own benefit.

2 Apr 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019

Sweden shows greatest improvement in saving extremely preterm babies

The survival rate among extremely preterm babies has greatly improved in Sweden, a country that offers top-class neonatal care, a study led from Karolinska Institutet published in the esteemed journal JAMA reports.

27 Mar 2019

Scientists identify mechanism of impaired wound healing in diabetes

Researchers at Karolinska Institutet have identified a mechanism that can explain the impaired wound healing in diabetes which can lead to diabetic foot ulcers. The study is published in the scientific journal PNAS, Proceedings of the National Academy of Sciences.

26 Mar 2019

Study shows how some autoimmune diseases are more closely related than others

Researchers using the world's largest twin registry to study seven autoimmune diseases found the risk of developing the seven diseases is largely inherited, but that some diseases are more closely related than others.

25 Mar 2019

Scientists find new proof that narcolepsy is an autoimmune disease

Researchers from the University of Copenhagen have discovered autoreactive cells in persons suffering from narcolepsy.

15 Mar 2019

New mathematical method to map cell regulatory networks

Faster results. Lower costs. Fewer cells. A new mathematical method developed by researchers at Cincinnati Children's and New York University may soon make it much easier to conduct more of the complex data analysis needed to drive advances in the exploding field of personalized medicine.

6 Mar 2019

Viruses in the intestinal tracts can lead to islet autoimmunity and Type 1 diabetes

Researchers at the Center for Infection and Immunity at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association between elevated levels of enteroviruses in the intestinal tracts of children and islet autoimmunity, a precursor to Type 1 diabetes.

20 Feb 2019

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

Discovery of a 'master switch' within the immune system

Researchers Professor Graham Lord, from The University of Manchester and colleagues have found that a specific part of the immune system could have the tools that may help in the therapy of some major diseases such as diabetes, cancer, multiple sclerosis, Crohn’s disease and other autoimmune diseases.

14 Feb 2019