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Targeted therapy doubles progression-free survival in rare bile duct cancer

Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy – including a near doubling of progression-free survival compared to expectations with standard of care – in previously treated patients with advanced NRG1-positive cholangiocarcinoma.

2 Jul 2026

Simple donor message could expand stem cell transplant options

When a patient needs a stem cell transplant, finding a registered donor is only the first step. Some potential donors drop out before confirmatory typing, reducing the pool from which doctors can choose.

2 Jul 2026

Community-based programs show greater promise for dementia prevention efforts

Nearly half of dementia cases could be prevented by tackling modifiable risk factors such as physical inactivity, smoking, low education or social isolation, but new Curtin University research suggests current public health approaches are falling short of driving real behaviour change.

2 Jul 2026

ACMG issues guidance for reporting uncertain genetic test variants

The American College of Medical Genetics and Genomics (ACMG) has published a new statement, Points to Consider for the Reporting of Variants of Uncertain Significance in Germline Genetic and Genomic Testing, providing guidance to laboratories and healthcare professionals on the reporting and communication of variants of uncertain significance (VUS) identified through genetic and genomic testing.

1 Jul 2026

KFF poll finds vaccine myths reach many Americans but convince few

KFF’s 2026 tracking poll found that many U.S. adults have heard common vaccine myths, including false claims about MMR, COVID-19, mRNA vaccines, and measles vaccines. Fewer adults strongly believe these myths, but a large, uncertain “malleable middle” remains, especially among those without a trusted health care provider, frequent social media users, some AI health-information users, and parents who delayed or skipped childhood vaccines.

1 Jul 2026

Compulsive smartphone use linked to higher depression risk in older adults

Compulsive smartphone habits in older adults can be linked to a higher risk of depression, according to a study led by a Rutgers researcher.

1 Jul 2026

New safety strategies reduced serious surgical events in children

Ann & Robert H. Lurie Children's Hospital of Chicago achieved more than a 13-fold improvement in surgical safety after implementing a series of interventions based on high reliability principles across its operating rooms.

1 Jul 2026

Mechanical restraint may increase short-term blood clot risk in psychiatric patients

Mechanical restraint is associated with a small increased short term risk of blood clots among inpatients at psychiatric hospitals, finds a Danish study published by The BMJ today.

1 Jul 2026

Engineered CAR T cells show promise against myeloproliferative neoplasms

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, in new research led by UCL and University of Oxford researchers.

1 Jul 2026

EULAR project reveals large disparities in European rheumatology care

Rheumatic and musculoskeletal diseases (RMD) are responsible for significant disability, and result in long-term work loss or early retirement.

1 Jul 2026

Novel biomimetic peptide actively rebuilds damaged tooth dentin

Dentin hypersensitivity affects millions of people worldwide, yet existing treatments often provide only temporary relief.

1 Jul 2026

Personalized self-management effectively prevents chronic back pain

Almost everyone will deal with back pain at some point in their lives. Most recover quickly - but for about 20% of people, acute pain becomes a chronic condition that interferes with daily life and keeps them out of the workforce.

1 Jul 2026

New bacterial enzyme blueprint could accelerate cancer treatment development

A team of researchers at the University of Warwick and Monash University has solved a puzzle that's stumped drug developers for decades: how bacteria naturally create multiple versions of powerful cancer therapies.

1 Jul 2026

New national program targeting harmful and unnecessary medicine use in Australia

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1 Jul 2026

Trial evaluates interdisciplinary care for veterans with brain trauma and PTSD

The Medical College of Wisconsin (MCW) is leading a new multi-center clinical trial to evaluate an interdisciplinary rehabilitation model for military veterans and first responders with mild traumatic brain injury (mTBI) and co-occurring disorders such as depression, anxiety, and post-traumatic stress disorder (PTSD).

30 Jun 2026

New trial shows oral therapy increases growth in children with achondroplasia

New findings from a trial conducted at Children's Hospital Colorado (Children's Colorado) and University of Colorado (CU) Anschutz School of Medicine demonstrate significantly increased growth rates in children with achondroplasia, the most common form of dwarfism.

30 Jun 2026

New structural insights overturn old assumptions about malaria entry

For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a ring-shaped structure called the moving junction.

30 Jun 2026

Breast milk sugars help shape infant gut microbiota during weaning

Research from DTU and Rigshospitalet shows that sugars in breast milk play an important role in the development of the gut microbiota, during weaning or transition from breast milk to solid food.

30 Jun 2026

First-in-human trial tests safer T-cell therapy for pediatric brain cancers

Researchers report encouraging early results from a first-in-human clinical trial led by Children's National using a new T-cell immunotherapy for children and young adults with some of the deadliest brain tumors, including diffuse intrinsic pontine glioma (DIPG) and relapsed central nervous system (CNS) tumors.

30 Jun 2026

Japanese study links inherited genetic variants to multiple lung cancers

Lung cancer remains the leading cause of cancer-related deaths worldwide and is generally thought to arise from mutations acquired over a lifetime through environmental exposures.

30 Jun 2026