Genetic Engineering News and Research

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Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

Lowering levels of a hormone called PTHrP can prevent metastases and improve survival in mice with pancreatic cancer and could lead to a new way to treat patients, according to a study from cancer researchers at Columbia University Vagelos College of Physicians and Surgeons and Herbert Irving Comprehensive Cancer Center and with collaborators at the University of Pennsylvania.

1 Jul 2021

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, and Nippon Gene Co., Ltd (Nippon Gene), a manufacturer of genetic engineering research reagents and diagnostic reagents for humans, animals, and plants, today announced a non-exclusive license agreement granting Nippon Gene access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

1 Jul 2021

Researchers identify proteins that contribute to the pathogenicity of COVID-19 virus

Researchers at Texas Biomedical Research Institute (Texas Biomed) have narrowed down the proteins enabling SARS-CoV-2 to cause disease.

1 Jul 2021

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis.

30 Jun 2021

Suzukii flies produce only males after mating, shows study

Populations of Drosophila suzukii fruit flies - so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America - could be greatly suppressed with the introduction of genetically modified D. suzukii flies that produce only males after mating, according to new research from North Carolina State University.

30 Jun 2021

Research shines new light on deadly medulloblastoma metastases

With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, or metastasize.

29 Jun 2021

The technology behind face masks that can diagnose COVID-19

Researchers have recently incorporated technology into standard face masks to detect the presence of SARS-CoV-2.

29 Jun 2021

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Researchers at the University of Chicago and the U.S. Department of Energy's (DOE) Argonne National Laboratory have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain.

29 Jun 2021

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

A new review article published in the journal Antibiotics reports the presence of a large number of bioactive compounds in microalgae that target chemical structures present only in their structure.

28 Jun 2021

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.

28 Jun 2021

First CRISPR-Cas9-based gene drive cuts and copies genetic elements in Arabidopsis plants

With a goal of breeding resilient crops that are better able to withstand drought and disease, University of California San Diego scientists have developed the first CRISPR-Cas9-based gene drive in plants.

25 Jun 2021

Mayo Clinic researchers are working toward new CAR-T cell treatment for multiple myeloma

Researchers at Mayo Clinic Cancer Center are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment for multiple myeloma.

25 Jun 2021

Increasing novel lncRNA in cardiomyocytes can inhibit the progression of heart failure

A research collaboration based in Kumamoto University (Japan) has identified a novel lncRNA, Caren, that is abundantly expressed in cardiomyocytes.

23 Jun 2021

Three CU researchers recognized for contributions to immunotherapy in childhood cancer

Three members of the University of Colorado Cancer Center and a longstanding supporter of the campus are part of a group of more than 200 researchers nationwide who were recognized in April with the Team Science Award from the American Association for Cancer Research.

23 Jun 2021

Enzyme in fat tissue helps control the production of new bone and fat cells, study shows

An enzyme found in fat tissue in the center of our bones helps control the production of new bone and fat cells, shows a study in mice published today in eLife.

22 Jun 2021

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

COVID-19 therapies made from antibodies often are given to patients who are at high risk of severe illness and hospitalization. However, there have been nagging questions about whether such antibody therapies retain their effectiveness as worrisome new virus variants arise.

21 Jun 2021

Unrepaired DNA damage can increase the speed of aging, study suggests

Every day, our bodies face a bombardment of UV rays, ozone, cigarette smoke, industrial chemicals and other hazards.

21 Jun 2021

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

By the time people with Alzheimer's disease start exhibiting difficulty remembering and thinking, the disease has been developing in their brains for two decades or more, and their brain tissue already has sustained damage. As the disease progresses, the damage accumulates, and their symptoms worsen.

21 Jun 2021

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Recently, researchers discuss their development of cell membrane-based nanoparticles that successfully delivered dexamethasone directly to inflamed lung cells.

21 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Genetic Engineering News and Research

Loss of PTHrP hormone can prevent metastases, improve survival in mice with pancreatic cancer

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

Researchers identify proteins that contribute to the pathogenicity of COVID-19 virus

Reduced function of key gene may affect communication between motor neurons and muscles in ALS

Suzukii flies produce only males after mating, shows study

Research shines new light on deadly medulloblastoma metastases

The technology behind face masks that can diagnose COVID-19

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Could microalgae-derived antiviral compounds combat SARS-CoV-2 and other viruses?

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

First CRISPR-Cas9-based gene drive cuts and copies genetic elements in Arabidopsis plants

Mayo Clinic researchers are working toward new CAR-T cell treatment for multiple myeloma

Increasing novel lncRNA in cardiomyocytes can inhibit the progression of heart failure

Three CU researchers recognized for contributions to immunotherapy in childhood cancer

Enzyme in fat tissue helps control the production of new bone and fat cells, study shows

Dual-antibody combination therapies effective against SARS-CoV-2 variants in animal study

Unrepaired DNA damage can increase the speed of aging, study suggests

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Study: Cancer cells grown in culture dishes have less parity with their human sources

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo