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New gene editing approach offers hope for cystic fibrosis patients

UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human airway cells, restoring key biological function in a laboratory model of cystic fibrosis and establishing a potential new path toward mutation-agnostic gene therapy for inherited lung diseases.

17 Feb 2026

Harnessing AI to optimize the development of new protein manufacturing processes

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds.

17 Feb 2026

Frozen in time: Ancient bacteria reveal evolution of drug resistance

Bacteria have evolved to adapt to all of Earth's most extreme conditions, from scorching heat to temperatures well below zero.

17 Feb 2026

ARVCF gene deletion leads to abnormalities in reward behavior

The ventral tegmental area (VTA) is a key brain region for dopamine production and the regulation of reward-related behaviors.

13 Feb 2026

Protrusion-derived extracellular vesicles boost functional cargo transfer

Extracellular vesicles (EVs) are tiny membrane-bound particles released by cells to transport proteins and other molecules to neighboring cells. Because of this natural delivery ability, EVs have attracted growing interest as potential vehicles for therapeutic protein and genome-editing enzyme delivery.

13 Feb 2026

Causal gene mapping identifies key drivers of Alzheimer's disease progression

Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & Public Health have created the most detailed maps to date showing how genes causally regulate one another across different types of brain cells affected by Alzheimer's disease.

13 Feb 2026

Genetic variants in 11 regions of human genome influence the gut microbiome

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there.

13 Feb 2026

FDA-approved anti-seizure drug could help fight Alzheimer's disease

While physicians and scientists have long known Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced.

12 Feb 2026

Defective ASTN1 gene linked to developmental delay and neurological disorders

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development.

10 Feb 2026

Researchers uncover mechanisms of three mismatch repair deficient high-grade glioma subtypes

Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas.

10 Feb 2026

Engineered wax moths offer ethical alternative to rodents used in research

A scientific breakthrough not only promises faster testing for antimicrobial resistance, but also an ethical solution to the controversial issue of using rodents in research.

10 Feb 2026

New analysis reveals hidden complexity in the vaginal microbiome

For decades, gynecological tests have relied on a simplified view of the vaginal microbiome, categorizing bacteria as either "good" or "bad."

6 Feb 2026

Rapid malaria resistance evolution in Sudanese Coptic populations

The study published in PNAS sets out how, in just 1,500 years, the Copts have acquired a genetic variant that protects them from contracting malaria after mixing with other Sudanese populations.

6 Feb 2026

Early biomarkers predict infections after breast reconstruction surgery

In the U.S., one in eight women will get breast cancer in their lifetime, and about half of them will have mastectomies.

5 Feb 2026

Computational method clarifies microbial signals in tumor sequencing

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

5 Feb 2026

Next-generation sequencing expands possibilities for newborn screening

Every year, millions of newborns undergo routine screening as a preventive strategy to detect inherited disorders before symptoms emerge.

4 Feb 2026

New liquid biopsy detects early cancers through epigenetic instability

Researchers at the Johns Hopkins Kimmel Cancer Center have developed a novel liquid biopsy approach to identify early-stage cancers by measuring the random variation in DNA methylation patterns, rather than the absolute level of those patterns as in other liquid biopsies.

2 Feb 2026

Bat viruses in Indochina Peninsula reveal viral diversity, PEDV origins, and spillover risks

Bats, critical reservoirs of viruses with significant cross-species spillover risks, have long been understudied in the Indochina Peninsula.

2 Feb 2026

Scientists create new map showing how cancer gene mutations influence tumor growth

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth.

2 Feb 2026

Genetic ancestry influences tumor biology and survival in head and neck cancers

Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).

31 Jan 2026