Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Scientists discover role of two specific HOX genes in colon cancer development

In breakthrough colon cancer research, scientists at Christiana Care Health System's Center for Translational Cancer Research of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 genes in colon cancer stem cells promotes cell replication and contributes to the overpopulation of stem cells that drives colon cancer development.

31 Jan 2018

New organ-on-a-chip technology provides simple setting to study blood vessel formation

Researchers at the Institute of Industrial Science, the University of Tokyo, CNRS and INSERM, report a new organ-on-a-chip technology for the study of blood vessel formation and drugs targeting this event.

31 Jan 2018

Researchers use biomimetic engineering approach to develop vascular grafts

When a patient with heart disease is in need of a vascular graft but doesn't have any viable veins or arteries in his or her own body, surgeons can rely on synthetic, tissue-engineering grafts.

24 Jan 2018

Scientists take tissue-engineering approach to improve healing related to skeletal system

"Take a knee." "On bended knee." A "knee-slapper." "The bee's knees." The knee certainly carries a lot of weight in the English language, just as it does in the body. As the largest and one of the most complicated joints, the knee is also one of the most easily injured.

23 Jan 2018

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the "gene scissors" to the tumor cell genome.

22 Jan 2018

Researchers develop adhesive materials to prevent bracket stains on teeth

Researchers from Valencia (Spain), London (England) and Sul (Brazil) have performed research to develop adhesive materials that will prevent white stains from appearing on the teeth of people who use brackets.

19 Jan 2018

Novel robot can aid treatment of rare birth defect

Researchers at the University of Sheffield and Boston's Children Hospital, Harvard Medical School have created a robot that can be implanted into the body to aid the treatment of esophageal atresia, a rare birth defect that affects a baby's esophagus.

19 Jan 2018

New biomaterials-based system improves T-cell production

T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, chemical-based approaches.

18 Jan 2018

Scientists develop unique technique to map elasticity of cell components

Scientists at Université de Montréal have developed a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell.

17 Jan 2018

Genes involved in spinal cord repair of lamprey also present in mammals, study reveals

Many of the genes involved in natural repair of the injured spinal cord of the lamprey are also active in the repair of the peripheral nervous system in mammals, according to a study by a collaborative group of scientists at the Marine Biological Laboratory and other institutions.

16 Jan 2018

Lamprey genes provide clues to repair spinal cord damage, finds study

Researchers have found that several genes within an ancient species of fish can be used to provide clues in the treatment of spinal cord damage. The study titled, “Highly Conserved Molecular Pathways, Including Wnt Signaling, Promote Functional Recovery from Spinal Cord Injury in Lampreys,” appeared in the latest issue of the journal Scientific Reports.

15 Jan 2018

Researchers uncover powerful new model for studying hallmark of vascular disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

9 Jan 2018

Phase III clinical study of regenerative therapy for treating damaged cartilage has started

A group of researchers at Osaka University developed a synthetic tissue using synovium-derived mesenchymal stem cells (MSCs) for treating damaged cartilage, which had previously been incurable and had no effective therapies.

4 Jan 2018

Bioengineers reveal how to recreate complex folded shapes from living tissue

Many of the complex folded shapes that form mammalian tissues can be recreated with very simple instructions, UC San Francisco bioengineers report December 28 in the journal Developmental Cell.

30 Dec 2017

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

LSUHealthNO breakthrough may pave way for advances in obesity-related diseases

For the first time, researchers led by Frank Lau, MD, Assistant Professor of Clinical Surgery at LSU Health New Orleans, have successfully kept white fat tissue alive outside of the body for up to eight weeks.

11 Dec 2017

New study describes unique bioengineered tissue construct for modeling colorectal cancer

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix.

6 Dec 2017

Newcastle scientists develop new technique that revolutionizes cell culture

A technique which revolutionizes cell culture by allowing the continuous production and collection of cells, has been developed by scientists at Newcastle University.

28 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Orthocell earns CE Mark approval for CelGro collagen medical device

Regenerative medicine company Orthocell Limited is pleased to announce receipt of European regulatory approval (CE Mark) for its CelGro collagen medical device.

8 Nov 2017