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Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report.

4 Jul 2018

New computational strategy used to identify genes associated with childhood cancer

Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer.

3 Jul 2018

LLNL employs high-performance computing for better understanding of TBI

Since the wars in Afghanistan and Iraq began in 2001, more than 350,000 cases of traumatic brain injury in servicemen and women have been reported to the Department of Defense.

3 Jul 2018

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

New computational method improves ability to track spread of cancer cells

Princeton researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another.

30 Jun 2018

Computational biological models help uncover wealth of knowledge about atherosclerosis

Researchers have identified a new gene-activation pathway caused by lipids associated with coronary artery disease, a finding that could help identify new directions in research and drug development. The study was published in June in Nature Communications.

29 Jun 2018

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Clinical laboratories often rely on medical articles and public information on gene disease associations in determining the genes to include on genetic testing panels for specific conditions or the specific results to return to patients.

29 Jun 2018

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

A human virus that causes a rare form of leukemia increases the risk of disease by changing the way DNA loops inside our cells.

29 Jun 2018

Study focuses on sexual habits of fungus that causes athlete's foot

The sexual habits of Trichophyton rubrum, the fungus that causes athlete's foot and other kinds of skin and nail infections, were the focus of a study published by Brazilian scientists and international collaborators in the journal Genetics.

29 Jun 2018

UH scientists uncover clues to why bacteria survive in space

In professor George Fox's lab at the University of Houston, scientists are studying Earth germs that could be contaminating other planets.

28 Jun 2018

Study shows precision medicine improves outcomes in pancreatic cancer patients

A study published today by the Pancreatic Cancer Action Network, Perthera, Inc., and colleagues in the AACR journal Clinical Cancer Research found for the first time that precision medicine can improve outcomes and provide clinically meaningful information to pancreatic cancer patients.

28 Jun 2018

MDxHealth releases positive data demonstrating value of SelectMDx test for prostate cancer patients

MDxHealth SA, today announced the publication of positive data demonstrating the value of the SelectMDx liquid biopsy test for Prostate Cancer in guiding patient management for men being considered for multiparametric MRI and the clinical utility in guiding biopsy decisions in real-world clinical practice.

From MDxHealth 28 Jun 2018

Rethinking current method paves way for new, personalized cancer diagnostics

All diseases have a genetic component. Advances in understanding the genetic mechanisms behind these disease enables the development of early diagnostic tests, new treatments, or interventions to prevent disease onset or minimize disease severity.

28 Jun 2018

Error in most widely used method in epigenetics can cause misleading results

An error in one of the most widely used methods in epigenetics, DIP-seq, can cause misleading results, researchers at Linköping University, Sweden, have shown. This may have major significance in the research field, where "big data" and advanced methods of DNA analysis are used to study vast amounts of epigenetic data.

26 Jun 2018

Special collection of papers highlights research on craniofacial genetics

Our faces can reveal a lot about us, and now scientists are revealing a lot about faces. PLOS Genetics announces a special collection of papers to highlight recent advances in our understanding of how faces form, curated by Seth Weinberg of the University of Pittsburgh, and colleagues.

26 Jun 2018

Cholera transmission tracked at household level across Dhaka

For the first time, the transmission of cholera has been tracked at the household level across Dhaka, Bangladesh, a city with a 'hyper-endemic' level of the disease.

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Herpes may play role in pathogenesis of Alzheimer’s

Herpes virus present within the body long after the overt infection may play a role in the pathogenesis of Alzheimer’s disease say researchers. The study titled, “Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus” appeared in the latest issue of the journal Neuron, this Thursday.

22 Jun 2018

Researchers report unusually high levels of herpesvirus in the brains of people with Alzheimer's disease

Two strains of human herpesvirus - human herpesvirus 6A (HHV-6A) and human herpesvirus 7 (HHV-7) - are found in the brains of people with Alzheimer's disease at levels up to twice as high as in those without Alzheimer's, researchers from the Icahn School of Medicine at Mount Sinai report.

21 Jun 2018

Genomic News and Research

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

New computational strategy used to identify genes associated with childhood cancer

LLNL employs high-performance computing for better understanding of TBI

New biomarker paves way for personalized bladder cancer treatments

New computational method improves ability to track spread of cancer cells

Computational biological models help uncover wealth of knowledge about atherosclerosis

Only one of 21 genes in BrS genetic test found to be associated with Brugada Syndrome

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

Study focuses on sexual habits of fungus that causes athlete's foot

UH scientists uncover clues to why bacteria survive in space

Study shows precision medicine improves outcomes in pancreatic cancer patients

MDxHealth releases positive data demonstrating value of SelectMDx test for prostate cancer patients

Rethinking current method paves way for new, personalized cancer diagnostics

Error in most widely used method in epigenetics can cause misleading results

Special collection of papers highlights research on craniofacial genetics

Cholera transmission tracked at household level across Dhaka

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Herpes may play role in pathogenesis of Alzheimer’s

Researchers report unusually high levels of herpesvirus in the brains of people with Alzheimer's disease

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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