Cell Death News and Research

RSS

Strawberries most effective at inducing cancer cell death

Strawberries may be the most effective of the five most commonly consumed berries at inducing cancer cell death, according to a recent study conducted at the UCLA Center for Human Nutrition.

10 Aug 2005

Protein p53 is the "guardian" of our genome

When DNA damage is present, p53 stops cell division and gives the cell enough time to repair it. If the damage is irreparable, the protein sets off programmed cell death and protects the cells from degeneration.

7 Aug 2005

Living Cell Technologies announces results for treating Huntington's disease

Living Cell Technologies announced pre-clinical results today showing its brain protection product, NeurotrophinCell (NtCell) produces a marked reduction in the size of brain lesions in a Huntington's disease (HD) model.

2 Aug 2005

Action of dopamine may be particularly important for understanding psychiatric conditions

Duke University Medical Center researchers have discovered a new mechanism by which chronically high levels of the neurotransmitter dopamine exert their effects on the brain.

28 Jul 2005

New way to prevent macular degeneration

Two studies from an unusual research partnership at the University of Chicago appear to have resolved a long-standing dispute about the role of melanin in the eye. The studies, one published in the Proceedings of the National Academy of Sciences (PNAS) and one early online in the Journal of the American Chemical Society (JACS), also suggest a new way to prevent a common cause of blindness.

28 Jul 2005

Decreased breast cancer survival associated with high TRAIL-R2 expression

High expression of TRAIL-R2, a cell surface receptor that triggers cell death, has been shown to be associated with a decrease the survival rates of breast cancer patients according to a study published by Yale Cancer Center researchers in Clinical Cancer Research.

25 Jul 2005

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

The findings, which appear in the July issue of the journal Molecular Cancer Therapeutics, could lead to a treatment that provides an effective option to surgically removing the cancer, helping patients preserve vital organs involved in speech and swallowing.

18 Jul 2005

New theory on aging says popping pills and drinking orange juice no guarantee you'll live longer

In direct contrast to previous reports, researchers now say that drinking gallons of orange juice and popping vitamin pills may not be a guarantee that you will live longer.

18 Jul 2005

New molecular insights may one day lead to opportunities to stave off old age

Delving deep into the molecular subtleties of a strain of mice engineered to age rapidly, scientists have found that an accumulation of genetic mutations prompts a cascade of programmed cell death that seems to underpin the aging process.

18 Jul 2005

Researchers have discovered a key regulatory molecule for Huntington's disease

Researchers have discovered a key regulatory molecule whose overactivation by the abnormal protein produced in Huntington's disease (HD) causes the central pathologies of the disease.

6 Jul 2005

Novel inhibitor offsets neurotoxic effects of tPA - possible new stroke treatments

A research team lead by the Burnham Institute has synthesized and tested a new series of inhibitors that can prevent the type of nerve cell injury and death associated with many neurodegenerative diseases and stroke.

6 Jul 2005

Study is the first to show that there are mechanisms in place for the immune system to identify cancer cells

A study undertaken by biologists at the University of California, Berkeley, has found that damage to a cell's DNA sets off a chain reaction that leads to the increased expression of a marker recognized by the body's immune system.

6 Jul 2005

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents through a cellular stress response that activates a pro-survival protein called GRP78, according to researchers from the Keck School of Medicine of the University of Southern California.

6 Jul 2005

Researchers find enzyme vital for controlling the early stages of cell death

Researchers at UT Southwestern Medical Center have found an enzyme vital for controlling the early stages of cell death - a beneficial and normal process when it works right, but malignant in a variety of cancers when it malfunctions.

30 Jun 2005

Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

AAV2 has great potential to be developed as an anti-cancer agent

Six days is all it takes for a common, non-disease-causing virus to kill cervical, breast, prostate and squamous cell cancer cells in laboratory cultures, according to Penn State College of Medicine researchers.

21 Jun 2005

Scientists identify inhibitors of the anthrax toxin

A collaborative team of scientists led by The Burnham Institute's Maurizio Pellecchia, Ph.D., has identified inhibitors of the anthrax toxin, termed lethal factor ("LF") that could be developed into an emergency treatment for exposure to inhalation anthrax.

21 Jun 2005

Women who have a special genetic profile can conceive spontaneously after the age of 45 years

Dr. Neri Laufer, from the Hadassah University Hospital, Jerusalem, Israel, told the conference that his team's work to identify a specific gene expression profile linked to later fertility would help understanding of the ageing process, as well as enabling the development of better treatments for infertility in older patients.

20 Jun 2005

Cockroach holds secret of women's fertility

The suggestion that a woman’s reproductive history may affect her ability to have children in the future has been a puzzle to scientists for years.

From The University of Manchester 16 Jun 2005

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

Cell Death News and Research

Strawberries most effective at inducing cancer cell death

Protein p53 is the "guardian" of our genome

Living Cell Technologies announces results for treating Huntington's disease

Action of dopamine may be particularly important for understanding psychiatric conditions

New way to prevent macular degeneration

Decreased breast cancer survival associated with high TRAIL-R2 expression

Compound derived from cottonseed could help improve the effectiveness of chemotherapy at treating head and neck cancer

New theory on aging says popping pills and drinking orange juice no guarantee you'll live longer

New molecular insights may one day lead to opportunities to stave off old age

Researchers have discovered a key regulatory molecule for Huntington's disease

Novel inhibitor offsets neurotoxic effects of tPA - possible new stroke treatments

Study is the first to show that there are mechanisms in place for the immune system to identify cancer cells

Cancer cells may be able to avoid destruction by anti-vascular and anti-angiogenesis agents

Researchers find enzyme vital for controlling the early stages of cell death

Study causes big shift in how we think about p53 gene

AAV2 has great potential to be developed as an anti-cancer agent

Scientists identify inhibitors of the anthrax toxin

Women who have a special genetic profile can conceive spontaneously after the age of 45 years

Cockroach holds secret of women's fertility

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics