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Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.

7 Dec 2023

A class of diabetes medications may reduce the risk of colorectal cancer

A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC).

7 Dec 2023

Study shows decline in post-surgery opioid prescriptions, but urges continued efforts

Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows.

7 Dec 2023

Researchers identify 25 new genetic markers linked to peptic ulcers

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations.

7 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

A systematic review and meta-analysis in Scientific Reports finds no significant difference between paracetamol and ibuprofen in treating episodic tension-type headaches, suggesting both as viable options for pain relief.

7 Dec 2023

COST's Network of Actions against COVID-19

Throughout history, infectious diseases have been a constant presence, and this is still the case today, with frequent outbreaks.

7 Dec 2023

New early phase study evaluates “on-demand” HIV prevention method for women

A fast-dissolving vaginal insert that women would use at or around the time of sex as an "on-demand" HIV prevention method is being evaluated in a new early phase study being conducted by MATRIX, a United States Agency for International Development (USAID)-funded project focused on the early research and development of innovative HIV prevention products for women.

7 Dec 2023

Dodging the Medicare enrollment deadline can be costly

Angela M. Du Bois, a retired software tester in Durham, North Carolina, wasn't looking to replace her UnitedHealthcare Medicare Advantage plan. She wasn't concerned as the Dec. 7 deadline approached for choosing another of the privately run health insurance alternatives to original Medicare.

7 Dec 2023

Colorado blames Biden team and drugmakers for delaying Canadian imports

Colorado officials say their plan to import cheaper medicines from Canada has been stymied by opposition from drugmakers and inaction by the Biden administration, according to a state report obtained by KFF Health News.

7 Dec 2023

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Peer-reviewed study published in Xenobiotica describes an innovative new method that predicts the routes and products of Phase I and II metabolism with high sensitivity and greater precision than other approaches.

From Optibrium Ltd. 7 Dec 2023

Ashwagandha extracts show promise in reducing stress hormones, study suggests

A systematic review reveals that Withania somnifera (Ashwagandha) extracts can effectively reduce cortisol levels in the short term, offering a natural alternative for stress management, though long-term effects remain unexplored.

6 Dec 2023

ANU research uncovers protein's role in autoimmune disease and cancer

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found.

6 Dec 2023

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

New drug combo fights breast cancer with brain metastases

A combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended progression-free survival among patients with unresectable locally advanced or metastatic HER2-positive breast cancer, compared with T-DM1 alone, according to results from the HER2CLIMB-02 trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

6 Dec 2023

MedUni Vienna scientists discover new pain medication with fewer side effects

People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects.

6 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers - only about one in eight patients survives five years after diagnosis.

6 Dec 2023

These programs put unused prescription drugs in the hands of patients in need

On a recent November evening, Angie Phoenix waited at a pharmacy here in Colorado's second-largest city to pick up prescription drugs to treat her high blood pressure and arm seizures.

6 Dec 2023

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

Researchers assessed ethnic and racial differences in novel hormonal therapy (NHT) use among advanced prostate cancer (PCa) patients.

6 Dec 2023

New consensus report highlights progress and potential of precision medicine in diabetes

A new international consensus report on precision medicine in diabetes prevention and care highlights the significant advancements in precision medicine in diabetes prevention, diagnosis, treatment, and prognosis while also shedding light on numerous knowledge gaps.

5 Dec 2023

Drugs News and Research

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

A class of diabetes medications may reduce the risk of colorectal cancer

Study shows decline in post-surgery opioid prescriptions, but urges continued efforts

Researchers identify 25 new genetic markers linked to peptic ulcers

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Paracetamol and ibuprofen equally effective for tension-type headaches, study reveals

COST's Network of Actions against COVID-19

New early phase study evaluates “on-demand” HIV prevention method for women

Dodging the Medicare enrollment deadline can be costly

Colorado blames Biden team and drugmakers for delaying Canadian imports

Optibrium’s Quantum Mechanics and Machine Learning Methods Predict Routes of Drug Metabolism

Ashwagandha extracts show promise in reducing stress hormones, study suggests

ANU research uncovers protein's role in autoimmune disease and cancer

Scientists uncover key protein aggregation in frontotemporal dementia

New drug combo fights breast cancer with brain metastases

MedUni Vienna scientists discover new pain medication with fewer side effects

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

These programs put unused prescription drugs in the hands of patients in need

Are there racial and ethnic disparities in the use of novel hormonal therapy agents in men with advanced prostate cancer?

New consensus report highlights progress and potential of precision medicine in diabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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