Inflammation News and Research

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Connection between mitochondrial metabolite and activation of inflammatory response revealed

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Study finds no association between gout and neurodegenerative diseases in the general population

A study published in Scientific Reports highlights that gout can increase the risk of Alzheimer’s disease and Parkinson’s disease in younger or overweight individuals. The study was conducted in a representative Korean population.

8 Mar 2023

Self-directed autoantibodies against certain chemokines may protect against long-COVID

A recent study published in the journal Nature Immunology discovered autoantibodies against chemokines following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

8 Mar 2023

Statin-related residual inflammation predicts cardiovascular events and mortality

A recent Lancet study assessed the importance of low-density lipoprotein cholesterol (LDLC) and high-sensitivity C-reactive protein (CRP) as risk predictors of cardiovascular death, cardiovascular events, and all-cause death among patients subjected to statins.

7 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

Long-term intermittent fasting can offer protection from heart-related COVID-19 complications

Intermittent fasting, especially when done over the course of decades, can have positive effects on metabolic and cardiovascular health.

7 Mar 2023

Artificial intelligence for the histological prediction of ulcerative colitis remission

In a recent study published in Gastroenterology, researchers assessed the effectiveness of artificial intelligence in the histological prediction of ulcerative colitis remission or clinical outcomes.

7 Mar 2023

What is the impact of consuming walnuts on the dietary intake of total polyphenols?

Researchers performed secondary analyses of the Walnuts and Healthy Aging study (WAHA) data.

7 Mar 2023

IgG4 serum levels do not show elevation in post-COVID syndrome

In a recent study posted to bioRxiv* preprint server, researchers in Germany assessed the differences in antigen-specific immunoglobulin G (IgG) subtypes between post-COVID syndrome (PCS) patients and convalescent controls.

6 Mar 2023

A measure of residual inflammatory risk may be a powerful predictor of future cardiovascular events

New evidence released today from a study of 31,245 patients already taking statin therapy indicates that inflammation may be a more powerful predictor of risk of future cardiovascular events - such as heart attack and stroke - than "bad" cholesterol.

6 Mar 2023

'Good autoantibodies' associated with a milder course and lower risk of long Covid

Sometimes in the laboratory there are unexpected results. "Previously it had been observed that autoantibodies are common in severe Covid patients, those who end up in intensive care," says Jonathan Muri, postdoctoral fellow at the Institute for Research in Biomedicine (IRB, affiliated with the Università della Svizzera italiana) and co-author of the study.

6 Mar 2023

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

Giving noncritically ill patients hospitalized for COVID-19 a higher dose of blood-thinning medication than usual did not significantly reduce the combined risk of death from any cause, need for treatment in an intensive-care unit, a confirmed blood clot or a stroke at 30 days, according to the results of the FREEDOM-COVID trial presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

Inflammation News and Research

Connection between mitochondrial metabolite and activation of inflammatory response revealed

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

COVID-19 patients at increased risk of developing gastrointestinal disorders

Study finds no association between gout and neurodegenerative diseases in the general population

Self-directed autoantibodies against certain chemokines may protect against long-COVID

Statin-related residual inflammation predicts cardiovascular events and mortality

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Long-term intermittent fasting can offer protection from heart-related COVID-19 complications

Artificial intelligence for the histological prediction of ulcerative colitis remission

What is the impact of consuming walnuts on the dietary intake of total polyphenols?

IgG4 serum levels do not show elevation in post-COVID syndrome

A measure of residual inflammatory risk may be a powerful predictor of future cardiovascular events

'Good autoantibodies' associated with a milder course and lower risk of long Covid

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Study finds cannabis vaping more harmful than nicotine vaping

Association between cardiovascular disease and transportation noise revealed in new research

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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