Proliferation News and Research

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Fatbuster drug targets obesity

A new drug to combat obesity at a cellular level is in the sights of a University of Queensland scientist.

25 Oct 2004

High levels of a protein called LRP6 can make cancer cells more aggressive

The protein's ability to enhance tumor development suggests that the gene that codes for LRP6 is an oncogene--a gene that contributes to tumor development when overactivated.

25 Oct 2004

Potential new protein marker for prognosis of breast and ovarian cancer

The researchers matched tumor samples to outcomes in about 100 patients diagnosed with either breast or ovarian cancer and found that a low level of Rab25 protein on a patient's cancer sample was associated with a better clinical outcome in both cancer types.

24 Oct 2004

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

According to new studies, sanguinarine was shown to enhance production of proteins that induce cell death, or apoptosis, in cells damaged by ultraviolet-B (UVB) radiation.

21 Oct 2004

Study will evaluate arsenic exposure from the environment and its potential carcinogenic effects

The National Cancer Institute has awarded the Arizona Cancer Center at the University of Arizona Health Sciences Center a three-year grant to evaluate associations between elevated arsenic exposure and cancer incidence in Arizona and Mexico.

19 Oct 2004

New genetic mechanism has been identified linking diet to breast cancer

Experiments carried out by scientists at the Universitat Autònoma de Barcelona on experimentally induced breast cancer tumours in laboratory rats show that an excess of certain fats in the diet, commonly known as omega-6, accelerates breast cancer, increasing the malignancy of the disease.

18 Oct 2004

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Duke University Medical Center researchers have shown that they can stimulate the body to produce its own naturally occurring growth factors to promote blood vessel growth into tissue damaged by peripheral arterial obstructive disease (PAOD).

13 Oct 2004

Discovery of a central memory form of helper T cells that can offer immunity to leishmaniasis

Researchers at the University of Pennsylvania have discovered a "central memory" form of "helper" T cells that can offer immunity to leishmaniasis, a disease that causes considerable death and disfigurement across the globe and has been found in U.S. military personnel returning from Afghanistan and Iraq.

8 Oct 2004

International society agrees that the potential of stem cells derived from fat show promising clinical uses

While questions still remain about the nature and function of stem cells found in fat, a group of researchers and clinicians convened today in Pittsburgh at the Second Annual Meeting of the International Fat Applied Technology Society (IFATS) agreed that research should move forward with the ultimate goal of performing human clinical trials to test the cells' therapeutic potential for specific indications.

5 Oct 2004

Significant progress in development of an animal model of smallpox that closely resembles human disease

Scientists have made significant progress in developing an animal model of smallpox that closely resembles human disease, which will be necessary for testing of future vaccines and potential treatments.

5 Oct 2004

Researchers discover new mechanism responsible for blood vessel tumors that cause facial deformities

Researchers have discovered a new mechanism responsible for the growth of blood vessel tumors that can cause facial deformities in infants and young children, paving the way for an antibody-based treatment to remove cells that fuel the tumors’ growth.

5 Oct 2004

A revolutionary approach to angiogenesis could make cancer treatment more effective at killing tumours

Dr. Olivier Feron and his team from the University of Louvain Medical School in Brussels have turned the whole concept of targeting tumour blood vessels on its head. Instead of the conventional approach of trying to starve tumour cells of the blood supply they need to grow, they are doing the opposite – opening up the tumour blood supply to allow better access for cancer drugs and more effective radiotherapy.

30 Sep 2004

Scientists embark on a five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues

A multidisciplinary team of scientists at the University of Illinois at Urbana-Champaign is embarking on a comprehensive five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues.

29 Sep 2004

Functions of the c-myb gene which leukemia cells depend on for proliferation

Today the Proceedings of the National Academy of Sciences publishes a paper by Temple University researchers that details one of the functions of the c-myb gene (which leukemia cells depend on for proliferation), the formation of white blood cells.

27 Sep 2004

New combination of drugs results in fewer incidences of rejection in liver transplant patients

“The big advantage [of this combination of drugs] is that the incidence of rejection is significantly decreased,” he says. “These results could change the standard of care for liver transplant recipients.”

23 Sep 2004

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

Drinking a glass of red wine a day may cut a man's risk of prostate cancer in half, and the protective effect appears to be strongest against the most aggressive forms of the disease

23 Sep 2004

New link in the growth of Ewing’s sarcoma

To develop new therapeutic approaches to cancer, it is essential to understand the long and extremely complex process that underlies it, in other words the various stages of cancer development from the initial mutation to the tumor.

23 Sep 2004

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Researchers at The University of Texas M. D. Anderson Cancer Center now have evidence that receptors found on tumors that were believed to function only on the surface of cells can actually switch on genes inside a cell's nucleus, thus promoting cancer development in two distinct ways.

21 Sep 2004

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

The eradication of brain tumors in mice following treatment with a novel drug suggests that certain cancers might one day be cured without the use of toxic chemotherapy and radiation.

20 Sep 2004

Protein points to anticancer drug targets

A unique tail at one end of a protein called Ubc12 stabilizes a molecular workshop that assembles the “on-switch cells” used to accelerate cell replication.

20 Sep 2004

Proliferation News and Research

Fatbuster drug targets obesity

High levels of a protein called LRP6 can make cancer cells more aggressive

Potential new protein marker for prognosis of breast and ovarian cancer

Common antibacterial and antifungal ingredient used in tooth paste may protect against skin cancer

Study will evaluate arsenic exposure from the environment and its potential carcinogenic effects

New genetic mechanism has been identified linking diet to breast cancer

Researchers stimulate the body to repair tissue damaged by peripheral arterial obstructive disease

Discovery of a central memory form of helper T cells that can offer immunity to leishmaniasis

International society agrees that the potential of stem cells derived from fat show promising clinical uses

Significant progress in development of an animal model of smallpox that closely resembles human disease

Researchers discover new mechanism responsible for blood vessel tumors that cause facial deformities

A revolutionary approach to angiogenesis could make cancer treatment more effective at killing tumours

Scientists embark on a five-year study of the effects of soy isoflavones found in dietary supplements on various body tissues

Functions of the c-myb gene which leukemia cells depend on for proliferation

New combination of drugs results in fewer incidences of rejection in liver transplant patients

Four or more glasses of red wine per week may reduce risk of prostate cancer by 50 percent

New link in the growth of Ewing’s sarcoma

HER-2 cell surface receptors tun on genes associated with carcinogenesis

Certain cancers might one day be cured without the use of toxic chemotherapy and radiation

Protein points to anticancer drug targets

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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