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Innovative computer modeling technique predicts how protein molecule behavior in response to environmental conditions

In a development that could have great significance for efforts to understand how the basic molecular machinery of life works, researchers at the University of Texas Medical Branch at Galveston (UTMB) have successfully applied an innovative computer modeling technique to predicting how protein molecules will behave in response to different environmental conditions.

15 Mar 2005

Discovery of key molecule that controls the growth, spread and survival of pancreatic cancer cells

Pancreatic cancer kills 30,000 Americans every year. Not only is there no cure, but there are no effective treatments. That may change if a new finding by Mayo Clinic researchers continues to show promise.

15 Mar 2005

Timing is everything when it comes to killing prostate cancer cells

"The window of opportunity is narrow for vaccination, designed to reinvigorate the immune system's attack on cancer cells, and it occurs right after hormonal therapy begins to wipe out the tumor and immune cells outnumber cancerous ones," according to Charles Drake, M.D., Ph.D.

15 Mar 2005

Use of potentially inappropriate medications among elderly common in some European countries

There are substantial differences between European countries in the potentially inappropriate use of medications among elderly home care patients, according to a study in the March 16 issue of JAMA.

15 Mar 2005

New study reveals little risk in insuring HIV positive patients

The Dutch Association of Insurers has announced the results of a study revealing there is little risk in providing life insurance policies to HIV patients in the Netherlands undergoing Highly Active Antiretroviral Therapy (HAART).

15 Mar 2005

Brewing up potential anti-cancer drugs from green tea

Drinking green tea has a protective effect against some forms of cancer but drinking large amounts can increase the risk of birth defects such as spina bifida – according to previous epidemiological studies.

15 Mar 2005

Research, advocacy and education must "close the gaps" in cardiovascular health disparities

Research, advocacy and education must "close the gaps" in cardiovascular health disparities among races, an American Heart Association writing group reports in today's special disparities issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Process behind cellular export of iron may help to explain human hemochromatosis

The first direct evidence that a single protein is critical in the cellular export of iron may help to explain human hemochromatosis, researchers report in the March issue of Cell Metabolism.

15 Mar 2005

New insight into key mechanism by which cells limit cholesterol

The finding suggests a novel approach to the development of cholesterol-lowering drugs that may boost the effect of statins, one of the most prescribed cholesterol inhibitors, according to researchers at the University of Texas Southwestern Medical Center.

15 Mar 2005

Blacks less likely to get expensive, newer heart treatments

Blacks who suffer the most common type of cardiac ischemia – non-ST-elevation acute coronary syndrome – are less likely than whites to receive expensive or newer evidence-based treatments, according to a report in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Decision to cut Alzheimer's drugs challenged

Four major drugs, the only drugs licensed in Britain for the treatment of Alzheimer's disease and available on the NHS may be withdrawn. Aricept, Exelon, Reminyl and Ebixa are the only drugs licensed in Britain for the treatment of the disease.

14 Mar 2005

Bird flu could kill 2 million Brits

A UK expert is warning that the bird flu pandemic is imminent and inevitable and two million Britons could die.

14 Mar 2005

2004 FDA drug complaints way up high

The Food and Drug Administration (FDA) received a record number of complaints regarding drug side effects and other related health problems in 2004, according to a published report.

14 Mar 2005

DNA sabotage may alleviate need for chemotherapeutic medication

Johns Hopkins chemists have discovered a new way to sabotage DNA's ability to reproduce, a finding that could eventually lead to the development of new anti-cancer drugs and therapies.

14 Mar 2005

£800,000 to boost research into fighting viruses

A team of University of Glasgow scientists have received a grant of £800,000 from the Wellcome Trust to research a mechanism that blocks a critical step in the replication cycle of retroviruses. In the long term, the research could lead to the design of new therapeutic strategies or drugs against retroviruses, which cause diseases such as AIDS and certain leukemias.

14 Mar 2005

New biocentre which will revolutionise the way future medicines are produced

The University of Manchester has been awarded £6m to open a new biocentre which will revolutionise the way future medicines are produced – making them safer and more effective.

From The University of Manchester 14 Mar 2005

Researchers identify biochemical target that could lead to a new class of antibiotics to fight TB

A worldwide health problem, tuberculosis kills more people than any other bacterial infection. The World Health Organization estimates that two billion people are infected with TB, and that two million people die each year from the disease.

14 Mar 2005

Naturally occurring antifungal agent in saliva kills oral pathogen responsible for most HIV-related oral infections

Oral biologists at the University at Buffalo have shown for the first time how histatin, the naturally occurring antifungal agent in saliva, kills the oral pathogen Candida albicans, the fungus responsible for most HIV-related oral infections.

14 Mar 2005

Research could lead to new drugs that combat HIV infection by shutting down the virus's assembly lines

After infecting a susceptible cell, the human immunodeficiency virus hijacks that cell's normal machinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and float off to invade other cellular factories.

14 Mar 2005

DNA weak links may provide clues to cancer biology

The chromosomes of mammals, including humans, contain regions that are particularly prone to breaking under conditions of stress and in cancer. Now, new research by geneticists at Duke University Medical Center finds that yeast cells also contain such weak links in DNA and begins to reveal the molecular characteristics of these links that might help to explain them.

13 Mar 2005

Drugs News and Research

Innovative computer modeling technique predicts how protein molecule behavior in response to environmental conditions

Discovery of key molecule that controls the growth, spread and survival of pancreatic cancer cells

Timing is everything when it comes to killing prostate cancer cells

Use of potentially inappropriate medications among elderly common in some European countries

New study reveals little risk in insuring HIV positive patients

Brewing up potential anti-cancer drugs from green tea

Research, advocacy and education must "close the gaps" in cardiovascular health disparities

Process behind cellular export of iron may help to explain human hemochromatosis

New insight into key mechanism by which cells limit cholesterol

Blacks less likely to get expensive, newer heart treatments

Decision to cut Alzheimer's drugs challenged

Bird flu could kill 2 million Brits

2004 FDA drug complaints way up high

DNA sabotage may alleviate need for chemotherapeutic medication

£800,000 to boost research into fighting viruses

New biocentre which will revolutionise the way future medicines are produced

Researchers identify biochemical target that could lead to a new class of antibiotics to fight TB

Naturally occurring antifungal agent in saliva kills oral pathogen responsible for most HIV-related oral infections

Research could lead to new drugs that combat HIV infection by shutting down the virus's assembly lines

DNA weak links may provide clues to cancer biology

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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