Aging News and Research

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Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

A possible protective genetic polymorphism in COVID-19

A new study discusses the role of a mucin gene enhancer on the clinical phenotype of the COVID-19.

5 Oct 2021

$35.1 million US grant focuses on investigating sleep disorder linked to neurodegeneration

People with rapid eye movement (REM) sleep behavior disorder act out their dreams. While sleeping safely in bed, for example, they might throw up their arms to catch an imaginary ball, or try to run from an illusory assailant.

5 Oct 2021

Managing metabolic disease through time-restricted eating

In this interview, News-Medical speaks to Dr. Satchin Panda about his latest research into time-restricted eating and how it can be used to manage metabolic diseases.

5 Oct 2021

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

Aging-US published "Cellular senescence in lymphoid organs and immunosenescence" which reported that immunosenescence is a multi-faceted phenomenon at the root of age-associated immune dysfunction.

5 Oct 2021

MR study finds no causal link between age at menarche or age at menopause and Alzheimer's risk

Aging-US published "The role of age at menarche and age at menopause in Alzheimer's disease: evidence from a bidirectional mendelian randomization study" which reported that the association between endogenous estrogen exposure and Alzheimer's disease remains inconclusive in previous observational studies, and few Mendelian randomization studies have focused on their causality thus far.

5 Oct 2021

Study assesses Texas nurses' COVID-19 vaccination status, intention, and hesitancy

New research focused on Texas nurses has found predictors of a lack of intention to be vaccinated against COVID-19 includes previous COVID-19 infection, unfavorable vaccine attitudes, and concerns about vaccine safety.

5 Oct 2021

Study sheds new light on the mechanisms required for development of adult-born neurons

A unique interaction between an excitatory neural receptor and a chloride transporter are critical for development of adult-born neurons in the dentate gyrus, according to a Northwestern Medicine study published in Cell Reports.

4 Oct 2021

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

It is well known that obesity affects the body's insulin production and over time risks leading to type 2 diabetes and several other metabolic diseases.

4 Oct 2021

Study finds cause and solution for complications in peritoneal dialysis

The number of patients suffering from chronic kidney disease or loss of kidney function is increasing worldwide and with it the number of people who need renal replacement therapy.

4 Oct 2021

Aging produces significant changes in the gut microbiome

Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The findings have been published in the journal Cell Reports.

3 Oct 2021

Additional supportive care services benefit older adults receiving chemotherapy, study finds

A clinical trial led by researchers at City of Hope, a world-renowned cancer research and treatment organization, showed that patients over 65 receiving chemotherapy experienced significantly fewer treatment-related side effects when a multidisciplinary team of experts analyzed each case and introduced personalized interventions.

30 Sep 2021

Immigration adds 1.4 to 1.5 years to U.S. life expectancy, study says

If immigrants to the United States formed their own country, their pre-COVID-19 life expectancies would exceed or match those of the world's leaders in longevity - Swiss men and Japanese women.

30 Sep 2021

Hippocampus connects separate, distant events to form narrative memories, study shows

People love stories. We find it easier to remember events when they are part of an overarching narrative. But in real life, the chapters of a story don't follow smoothly one from another. Other things happen in between.

30 Sep 2021

New study to evaluate community-based approach to helping children manage asthma symptoms

A new community-based approach to helping children manage their asthma symptoms will launch in up to 40 public, charter, and parochial schools across the Bronx, and enroll 416 students aged 4-12 years old.

29 Sep 2021

Columbia University and partners launch and operate New York City's first Pandemic Response Institute

Through a groundbreaking new award from New York City Economic Development Corporation (NYCEDC), Columbia University – through its Mailman School of Public Health – and a consortium of academic, community, government, and corporate partners will launch and operate New York City's first Pandemic Response Institute (PRI).

29 Sep 2021

Buck Institute receives $14 million NIH grant to focus on one of the major drivers of aging

Buck Institute professors Judith Campisi, PhD and Lisa Ellerby PhD, have been awarded a $14.3 million grant from the NIH's National Institute of Aging to study cellular senescence, one of the major hallmarks of aging, as a driver of Alzheimer's disease and other age-related dementias.

29 Sep 2021

Understanding noise-related hearing loss through changes in RNA levels

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions.

29 Sep 2021

Alzheimer’s drug targets people with mild cognitive impairment. What does that mean?

The approval of a controversial new drug for Alzheimer's disease, Aduhelm, is shining a spotlight on mild cognitive impairment — problems with memory, attention, language or other cognitive tasks that exceed changes expected with normal aging.

29 Sep 2021

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is a protein that tends to accumulate in increasing amounts, and the amount is strictly controlled by the splicing of TDP-43. Through cell experiments and analysis of human brain tissue, researchers at Brain Research Institute, Niigata University, led by Akihiro Sugai, M.D., Ph.D., have found that methylation of TDP-43 DNA is involved in the background of motor cortex involvement with aging in ALS

29 Sep 2021

Aging News and Research

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

A possible protective genetic polymorphism in COVID-19

$35.1 million US grant focuses on investigating sleep disorder linked to neurodegeneration

Managing metabolic disease through time-restricted eating

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

MR study finds no causal link between age at menarche or age at menopause and Alzheimer's risk

Study assesses Texas nurses' COVID-19 vaccination status, intention, and hesitancy

Study sheds new light on the mechanisms required for development of adult-born neurons

Study reveals the underlying mechanisms behind obesity and type 2 diabetes link

Study finds cause and solution for complications in peritoneal dialysis

Aging produces significant changes in the gut microbiome

Additional supportive care services benefit older adults receiving chemotherapy, study finds

Immigration adds 1.4 to 1.5 years to U.S. life expectancy, study says

Hippocampus connects separate, distant events to form narrative memories, study shows

New study to evaluate community-based approach to helping children manage asthma symptoms

Columbia University and partners launch and operate New York City's first Pandemic Response Institute

Buck Institute receives $14 million NIH grant to focus on one of the major drivers of aging

Understanding noise-related hearing loss through changes in RNA levels

Alzheimer’s drug targets people with mild cognitive impairment. What does that mean?

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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