Clinical Trial News and Research

RSS

Janssen’s vaccine added to list of safe, effective tools against COVID-19

The World Health Organization (WHO) today listed the COVID-19 vaccine Ad26.COV2.S, developed by Janssen (Johnson & Johnson), for emergency use in all countries and for COVAX roll-out. The decision comes on the back of the European Medicines Agency (EMA) authorization, which was announced yesterday.

16 Mar 2021

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC).

15 Mar 2021

An individualized approach to improve surgical outcomes after shoulder dislocation

A dislocated shoulder is a common sports injury that can occur with a single swing of the tennis racket or an awkward fall on the field. Though popping the bone back into the socket may seem like a simple solution, the reality is more complex.

13 Mar 2021

New vaccination method aims at comprehensive protection against all known influenza mutations

One shot, protected forever: This would be a dream come true regarding influenza vaccinations. So far, vaccination against influenza did not provide a lasting protection.

13 Mar 2021

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

In a study published in the journal Drugs, a researcher tackled the approval of Pfizer-BioNTech’s COVID-19 vaccine, which has now been used in many countries.

12 Mar 2021

NCCN publishes new guidance for management of COVID-19 in cancer patients

The National Comprehensive Cancer Network--an alliance of leading cancer centers--has published new best practice recommendations for Management of COVID-19 Infection in Patients with Cancer.

11 Mar 2021

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Henry Ford Cancer Institute is launching the Participatory Action for Access to Clinical Trials (PAACT) project to dramatically improve the representation of the African American community and other minorities in cancer clinical trials.

11 Mar 2021

Maternal pomegranate juice intake may reduce risk of brain injury in IUGR infants

Intrauterine growth restriction (IUGR) is common and concerning, but few therapeutic options exist for pregnant mothers who receive this diagnosis.

11 Mar 2021

Hydroxychloroquine has no effect in treating people with COVID-19, study shows

A year ago, infectious disease doctor Christine Johnston was leading a study on the use of hydroxychloroquine for the treatment of people with COVID-19.

10 Mar 2021

Bone marrow cell injections may lead to reduction in brain injury after stroke

Results of a clinical trial released in STEM CELLS Translational Medicine provide evidence that treating patients with an injection of bone marrow cells may lead to a reduction in brain injury after a stroke.

10 Mar 2021

mRNA COVID-19 vaccines show high efficacy in pregnancy and lactation

A reassuring study reports the immunogenicity and lack of reactogenicity of the coronavirus disease 2019 (COVID-19) vaccine when given to this group of subjects. This will contribute to the sum of knowledge about the implications of vaccination in this high-risk cohort.

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

Both ventral and dorsal surgeries improve outcomes in patients with cervical spondylotic myelopathy

Affecting the vast majority of people older than 65, cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord dysfunction in the United States and across the world.

10 Mar 2021

PRRT technology may offer new treatment approaches for neuroendocrine tumors

Neuroendocrine tumors are cancers that begin in specialized cells called neuroendocrine cells. These cells have traits similar to those of nerve cells and hormone-producing cells.

9 Mar 2021

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

Every 12 minutes, someone in the United States dies of pancreatic cancer, which is often diagnosed late, spreads rapidly and has a five-year survival rate at approximately 10 percent.

9 Mar 2021

Five herbal medicines show potent activity against Babesia duncani in the lab

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data finding that five herbal medicines had potent activity compared to commonly-used antibiotics in test tubes against Babesia duncani, a malaria-like parasite found on the West Coast of the U.S. that causes the disease babesiosis.

9 Mar 2021

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Translational research led by scientists at La Jolla Institute for Immunology (LJI) has resulted in a promising combination therapeutic candidate for adults with recent-onset type 1 diabetes.

9 Mar 2021

Study uncovers mechanism to help explain how maternal stress causes idiopathic preterm birth

Preterm birth is a leading cause of infant deaths and illness in the U.S. -- yet its underlying molecular causes remain largely unclear. About 40 to 50% of preterm births, defined as births before 37 weeks of pregnancy, are estimated to be "idiopathic," meaning they arise from unexplained or spontaneous labor.

9 Mar 2021

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

A two-week course of high doses of CBD helps restore the function of two proteins key to reducing the accumulation of beta-amyloid plaque, a hallmark of Alzheimer's disease, and improves cognition in an experimental model of early onset familial Alzheimer's, investigators report.

9 Mar 2021

Clinical Trial News and Research

Janssen’s vaccine added to list of safe, effective tools against COVID-19

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

An individualized approach to improve surgical outcomes after shoulder dislocation

New vaccination method aims at comprehensive protection against all known influenza mutations

An overview of the BNT162b2 COVID-19 vaccine by Pfizer-BioNTech

NCCN publishes new guidance for management of COVID-19 in cancer patients

Henry Ford Cancer Institute launches new initiative to improve minority participation in clinical trials

Maternal pomegranate juice intake may reduce risk of brain injury in IUGR infants

Hydroxychloroquine has no effect in treating people with COVID-19, study shows

Bone marrow cell injections may lead to reduction in brain injury after stroke

mRNA COVID-19 vaccines show high efficacy in pregnancy and lactation

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

Both ventral and dorsal surgeries improve outcomes in patients with cervical spondylotic myelopathy

PRRT technology may offer new treatment approaches for neuroendocrine tumors

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

Five herbal medicines show potent activity against Babesia duncani in the lab

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Study uncovers mechanism to help explain how maternal stress causes idiopathic preterm birth

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer