Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Racial differences in fatal coronary heart disease associated with risk factor burden

Despite treatment advances for coronary heart disease over the past 20 years, black men and women still have twice the risk of fatal coronary heart disease compared with white men and women, according to a study from the University of Alabama at Birmingham appearing in the Nov. 7, 2012 issue of the Journal of the American Medical Association.

6 Nov 2012

ECG analysis may predict risk of death from all causes

Research by Johns Hopkins cardiologists suggests that electrocardiograms (ECGs), which are widely used tests to assess the heart’s electrical activity, may have a greater and more profound future role in predicting the risk of death from any cause, not just heart problems.

6 Nov 2012

Detailing Medicare's 2013 doc pay schedules: Home health flat, primary care up

Under Medicare's 2013 payment schedule, released late last week, home health agency payments will remain flat while primary care physicians can expect up to a 7 percent boost in payments.

6 Nov 2012

Tengion receives U.S. patent allowance titled ‘Isolated Renal Cells and Uses Thereof’

Tengion, Inc., a leader in regenerative medicine, today announced that the United States Patent and Trademark Office (USPTO) has issued a Notice of Allowance for U.S. Patent Application No. 12/617,721, titled "Isolated Renal Cells and Uses Thereof."

5 Nov 2012

Living liver donors have QoL advantage

Living liver donors have a better quality of life than the general population, show the results of a Japanese study.

5 Nov 2012

Study highlights potential treatment that reduces kidney growth

Autosomal-dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders, affecting one in every 1,000 people and responsible for up to ten percent of patients on dialysis worldwide. The disease is characterized by the development of cysts that lead to progressive kidney failure and necessitate dialysis or a kidney transplant in most patients aged around fifty. Moreover, the persistent cyst growth causes high blood pressure and painful complications.

5 Nov 2012

New information related to kidney transplantation

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information related to kidney transplantation—specifically, the post-transplant health of kidney donors and the racial disparities faced by children in need of transplants.

3 Nov 2012

Health Net provides public with information on how to help prevent diabetes

With November being American Diabetes Month, Health Net, Inc. is providing the public with information on how to help prevent diabetes and how to help live an active lifestyle after being diagnosed with the condition.

3 Nov 2012

Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say.

3 Nov 2012

NY-Presbyterian/CUMC wins two Transplant Program Awards from HSS

NewYork-Presbyterian Hospital/Columbia University Medical Center was named a recipient of two Transplant Program Awards from the U.S. Department of Health and Human Services (HSS) for its outstanding performance on liver and lung transplantation.

3 Nov 2012

Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects

Genkyotex, the leading developer of NOX inhibitors to treat oxygen-radical mediated diseases, announced today that Phase I studies have demonstrated excellent safety and tolerability following single and multiple oral doses of GKT137831, the first in class NOX 1 and 4 inhibitor. In addition, GKT137831 demonstrated a favourable pharmacokinetic profile in these subjects.

3 Nov 2012

Study shows anxiety-promoting parental behaviors affect children

Parents with social anxiety disorder are more likely than parents with other forms of anxiety to engage in behaviors that put their children at high risk for developing angst of their own, according to a small study of parent-child pairs conducted at Johns Hopkins Children's Center.

3 Nov 2012

Studies provide new information on diet and blood pressure in kidney disease patients

Three studies presented during the American Society of Nephrology's Annual Kidney Week provide new information on diet and blood pressure in kidney disease patients.

3 Nov 2012

Bypass surgery offers people with diabetes better long-term survival than stents

People with diabetes mellitus who undergo heart bypass surgery for multiple blocked arteries have a significantly better 5-year-survival rate than diabetic patients who undergo angioplasty with drug-eluting stents (DES), according to a study published in the November 2012 issue of The Annals of Thoracic Surgery.

3 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

TD-1211 may relieve opioid-induced constipation

TD-1211 – an inhibitor of the mµ-opioid receptor – alleviates chronic noncancer-related constipation in patients receiving opioid therapy, without affecting pain relief, show the results of a parallel-group study.

2 Nov 2012

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Affymax, Inc. and Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) today announced the presentation of post-hoc sub-group analyses of the EMERALD Phase 3 studies that evaluated OMONTYS (peginesatide) Injection, an erythropoiesis-stimulating agent (ESA), for the treatment of anemia due to chronic kidney disease (CKD) in adult dialysis patients.

2 Nov 2012

FoXTROT results: preoperative chemo could become new standard

Preoperative chemotherapy is a feasible option for resectable advanced colon cancer, show results of the FoXTROT trial.

1 Nov 2012

Study finds link between severe sepsis and chronic diseases

It's a major cause of death, yet few of us have ever heard of it. Sepsis occurs when a patient's immune system overreacts to an infection, triggering a potentially fatal, system-wide inflammation. Severe sepsis strikes about 750,000 Americans each year, most of them older and often ill, with as many as half of these patients dying as septic shock shuts down their organs. Furthermore, patients in many Southern states are about twice as likely to develop sepsis for reasons unknown.

1 Nov 2012

Encouraging results from stereotactic radiosurgery Phase I trial on kidney cancer

A first-of-its-kind clinical trial conducted at University Hospitals (UH) Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer.

1 Nov 2012