immunity News and Research

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Is T-cell receptor sequencing a reliable alternative to SARS-CoV-2 antibody testing?

Researchers in the United States have now demonstrated that T-cell receptor (TCR) sequencing might provide a reliable alternative to assessing infection in convalescent blood plasma, and may be applicable in the future for applying protective immunity to individuals.

23 Mar 2021

COVID-19 vaccines reduce virus transmission in healthcare worker case study

In a new study, the ability of COVID-19 vaccines to lessen transmission was examined in a large study of healthcare workers and their families, with promising results that indicate a substantially reduced rate of transmission from the vaccinated to the non-vaccinated.

23 Mar 2021

Immunoassay heterogeneity and implications for SARS-CoV-2 serosurveillance

In a recent study, scientists have quantified anti-SARS-CoV-2 antibody levels up to 9 months after infection.

23 Mar 2021

A new COVID-19 candidate vaccine induces robust humoral and cellular immune responses in mice

A Korea-based company EyeGene Inc. has recently developed a liposome-based mRNA candidate vaccine against COVID-19, which contains full-length spike protein of the European variant (D614G) of SARS-CoV-2 as a vaccine antigen.

23 Mar 2021

‘Press 1 for English’: Vaccination sign-ups prove daunting for speakers of other languages

In late February, a week after Virginia launched a centralized website and call center for covid-19 vaccine preregistration, Zowee Aquino alerted the state to a glitch that could prove fatal for non-English speakers trying to secure a shot.

23 Mar 2021

COVID-19 antibodies can protect against reinfection for at least eight months

A new study offers hope that recovered patients from COVID-19 are largely immune to reinfection for at least eight months.

23 Mar 2021

Study suggests SARS-CoV-2 antibodies in breast milk are robust, neutralizing and durable

A new study addresses the issue of passive immunity to SARS-CoV-2 for newborns via breast milk.

23 Mar 2021

How could AI be used to predict infection outcomes?

Professor Frankel speaks to News-Medical about his latest research that investigated whether AI could be used to predict infection outcomes.

23 Mar 2021

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

In a paper recently uploaded to the preprint server bioRxiv by Tauzin et al. (March 18th, 2021) the ability of a single dose of mRNA vaccine to induce humoral and T cell responses against mutated variants are demonstrated and found to be reinforced in individuals with a history of COVID-19.

22 Mar 2021

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Although Tuberculosis, or TB, killed nearly as many people as COVID-19 (approx. 1.8 million) in 2020, it did not receive as much media and public attention.

22 Mar 2021

Researchers develop new method for measuring immunity to coronavirus

Igor Stagljar made his career building molecular tools to combat cancer. But when the pandemic hit last March, he aimed his expertise at a new adversary, SARS-CoV-2.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

To understand the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants (that are pathogenic) and other sarbecoviruses, a large team of researchers studied immunity by receptor-binding domain nanoparticle vaccines. They showed that a clinical-stage multivalent SARS-CoV-2 receptor-binding domain nanoparticle vaccine (SARS-CoV-2 RBD-NP) protected mice from the SARS-CoV-2-induced disease.

22 Mar 2021

Vaccine passports raise questions of equity, security, and privacy

Vaccine passports raise questions of equity, security, privacy, argues Crispin Maslog. China, where the COVID-19 pandemic began a long year ago, has now become the first country in the world to issue a vaccine passport to promote world economic recovery and facilitate cross-border travel.

22 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

The United States is a few days from reaching President Biden's goal of vaccinating 100 million people 100 days since he took office. While the United States leads the world in both the number of COVID-19 cases at over 29.7 million and deaths reaching past 539,000, it has stepped up as a leader in vaccinating its population.

21 Mar 2021

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

The results of a double-blind, randomized, multisite placebo-controlled trial that was conducted in South Africa show that Oxford’s ChAdOx1 nCoV-19 (AZD1222) vaccine has no efficacy against the B.1.351 variant in preventing mild-to-moderate coronavirus disease 2019 (COVID-19), and shows reduced neutralization properties of developed antibodies. The findings are published in the New England Journal of Medicine.

21 Mar 2021

immunity News and Research

Is T-cell receptor sequencing a reliable alternative to SARS-CoV-2 antibody testing?

COVID-19 vaccines reduce virus transmission in healthcare worker case study

Immunoassay heterogeneity and implications for SARS-CoV-2 serosurveillance

A new COVID-19 candidate vaccine induces robust humoral and cellular immune responses in mice

‘Press 1 for English’: Vaccination sign-ups prove daunting for speakers of other languages

COVID-19 antibodies can protect against reinfection for at least eight months

Study suggests SARS-CoV-2 antibodies in breast milk are robust, neutralizing and durable

How could AI be used to predict infection outcomes?

Single BNT162b2 mRNA dose induces humoral and T cell responses against mutated variants with a history of COVID-19

Iron-binder DFX improves the effect of new TB antimicrobial, research shows

Researchers develop new method for measuring immunity to coronavirus

Male fertility and androgen production may be impacted by COVID-19

Could nanoparticle vaccines offer broad protection against sarbecoviruses?

Vaccine passports raise questions of equity, security, and privacy

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

Research suggests SARS-CoV-2 vaccine distribution strategy focusing on where virus spreads more easily

ChAdOx1 nCoV-19 offers less protection against South African SARS-CoV-2 variant

Study: 8 out of 10 Spanish health professionals are willing to be vaccinated against COVID-19

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

New variant may not have changed COVID-19 pandemic course in UK, says study

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