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Targeting molecular mechanisms could be beneficial in diabetic wound care

When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down wound healing.

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Tandem radiation therapy effective in prostate cancer patients with no treatment options

Reports of new cancer treatments often raise high hopes and expectations, particularly, of course, among cancer patients and their families.

26 Nov 2019

Gut microbes can tamp down or boost the severity of norovirus infection

The highly contagious norovirus causes diarrhea and vomiting and is notorious for spreading rapidly through densely populated spaces, such as cruise ships, nursing homes, schools and day care centers. Each year, it is responsible for some 200,000 deaths, mostly in the developing world.

25 Nov 2019

Study about cells producing group E antibodies would help fight against allergies

Researchers of Sechenov University together with their colleagues from Russia and Austria summarized everything known about cells producing group E antibodies

25 Nov 2019

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

25 Nov 2019

PREDiCT: Tumor Models San Francisco Summit 2020

The community of preclinical immuno-oncology scientific Pharma and Biotechs meet again to advance their preclinical insights through robust models utilization to accelerate IO development & clinical confidence.

25 Nov 2019

Scientists record assembly of ribosomes in real time

A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes--the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms.

22 Nov 2019

New tool uses tiny circuits made of DNA to identify cancer cells

A new cancer-detecting tool uses tiny circuits made of DNA to identify cancer cells by the molecular signatures on their surface.

22 Nov 2019

Researchers discover new active substance effective against gram negative bacteria

More and more bacterial pathogens of infectious diseases become resistant to customary antibiotics. Typical hospital germs such as Escherichia coli and Klebsiella pneumoniae have become resistant to the most - and in some cases even all - currently available antibiotics. Their additional external membrane makes these bacteria difficult to attack.

21 Nov 2019

Extra DNA scooped up alongside cancer-causing genes helps drive tumor growth

One of the ways a cancer-causing gene works up enough power to turn a normal cell into a cancer cell is by copying itself over and over, like a Xerox machine.

21 Nov 2019

UTSA research aims to use sulfur to expedite new drug development

Organosulfur compounds are widely present in our bodies and the natural environment. They are found in onions, shallots and even cauliflower. Medical research finds that when consumed, they can protect against cancer, heart disease and even diabetes. There is also evidence of these compounds' antiviral and antibacterial uses. About a quarter of all pharmaceutical drugs currently use OSCs.

21 Nov 2019

Recently discovered protein may play key role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism.

21 Nov 2019

Inflammatory processes drive progression of neurodegenerative brain diseases

Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons.

20 Nov 2019

Carbon monoxide has a beneficial side at low concentrations

Most people think of carbon monoxide as harmful, and with good reason -- the colorless, odorless gas sends 50,000 people in the U.S. to hospitals each year when their furnaces malfunction or car engines run in poorly ventilated spaces. But at low concentrations, carbon monoxide has a beneficial side that scientists are trying to harness to treat diseases, according to an article in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Daltonics 20 Nov 2019

Dopamine may worsen lung inflammation in asthma

A new study on a mouse model of asthma shows that nerve cells producing dopamine, a neurotransmitter, signal T cells in the body to promote inflammation due to allergic reactions in the lungs during childhood but not in adult mice.

19 Nov 2019

Malaria research advances immunotherapy in lupus, HIV

A new study published on November 19, 2019, in the journal Cell Reports, shows how the body’s immune system responds to malaria, which in turn promises to teach scientists how to design more effective therapies for a range of illnesses that are modulated by the immune response.

19 Nov 2019