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Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc., has been allowed a patent by the Canadian Patent Office entitled "Antitumor Antisense Sequences Directed Against R1 and R2 Components of Ribonucleotide Reductase."

10 Nov 2004

Bretylium tosylate has unique benefits for patients with acute myocardial infarction

An "old" drug has unique benefits for patients with acute myocardial infarction (AMI; commonly known as heart attack), a finding that may contribute to a new understanding of how heart attacks develop, according to an article in the September/October American Journal of Therapeutics.

10 Nov 2004

Obesity statistics are as bogus as weight-loss scams

The weight-loss industry is finding itself in the crosshairs of the Federal Trade Commission's "Operation Big Fat Lies" -- a crackdown on slimming down pills, powders and patches that are too good to be true. The Center for Consumer Freedom (CCF) recommends that grossly exaggerated statistics and hype from pharmaceutical and weight-loss companies about the nation's so-called "obesity epidemic" also be placed under the federal microscope.

10 Nov 2004

Calcium channel blocker reduces adverse cardiovascular events

The calcium channel blocker amlodipine decreases the risk of cardiovascular events (such as heart attack or heart-disease related deaths) in patients with coronary artery disease and normal blood pressure, as does the ACE inhibitor enalapril, but to a lesser extent, according to a study in the November 10 issue of JAMA.

10 Nov 2004

Stem cell gene linked to a portion of one of the most common childhood brain cancers

Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability.

10 Nov 2004

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease, according to results of a study including UT Southwestern Medical Center at Dallas researchers.

9 Nov 2004

New strain of mice to study nicotine addiction

A team of investigators supported by the National Institute on Drug Abuse (NIDA), National Institutes of Health, has created a strain of mice scientists can use to study nicotine addiction and its associated behaviors.

9 Nov 2004

Discovery of new gene that protects against lung cancer

Cancer Research UK scientists have discovered a new gene that protects against lung cancer, according to a study published in the journal PNAS.

9 Nov 2004

FDA has warned consumers not to purchase or to consume Actra-Rx or Yilishen, promoted as "dietary supplements" for treating erectile dysfunction

The Food and Drug Administration today warned consumers not to purchase or to consume Actra-Rx or Yilishen, two products promoted and offered for sale on Web sites as "dietary supplements" for treating erectile dysfunction and enhancing sexual performance for men.

9 Nov 2004

Scientists have identified a fault in the brain waves of schizophrenics that may explain their hallucinations and disturbed thinking

The researchers studied the brain waves of normal and schizophrenic patients as they responded to images. Those with the disorder showed no electrical activity in a certain frequency-the “gamma” range, from 30 to 100 brain waves per second-that healthy brain cells use to exchange information about the environment and form mental impressions.

9 Nov 2004

Morton Grove Pharmaceuticals increases production of antiviral flu drug, Amantadine

During the current flu vaccine shortage, the Centers for Disease Control and Prevention, Department of Health and Human Services, has issued guidance recommending the use of certain alternative antiviral medications.

8 Nov 2004

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

Patients who suffer a loss of cognitive and motor function as a result of stem cell transplantation for severe blood disorders are likely to see those functions return to previous levels after one year, according to a new study in the November 15, 2004, issue of Blood, the official journal of the American Society of Hematology.

8 Nov 2004

ACE inhibitors not needed for many heart disease patients

Many heart disease patients who are already receiving state-of-the-art therapy do not benefit from additional treatment with angiotensin converting enzyme (ACE) inhibitors, according to results of a new study funded by the National Heart, Lung, and Blood Institute (NHLBI).

8 Nov 2004

Generic statin drugs shown to produce similar or better results than expensive brand-name drugs

Researchers from Kaiser Permanente's Northern California region are presenting a study at this week's American Heart Association Scientific Sessions showing that patients who use a generic statin drug rather than its brand-name equivalent fared as well as- sometimes better than-patients on the more expensive drug.

8 Nov 2004

Protease inhibitors used to treat HIV-1 infection may also be effective for treatment or prevention of malaria

The study found protease inhibitors inhibited the growth of P. falciparum, the malaria parasite that causes most disease. These findings may also expose a previously unexplored vulnerability in the parasite that could lead to a new class of anti-malarial drug.

8 Nov 2004

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers at Virginia Commonwealth University’s Massey Cancer Center have documented a novel form of resistance in leukemia cells to an anti-cancer drug, which could help scientists develop new strategies for treating the disease.

8 Nov 2004

Researchers attempt to quantify processes underlying cell heterogeneity

Combining the latest methods in gene splicing and computer modeling, Rice University researchers are trying to develop a predictive framework for one of the most basic and complex biological phenomena — cellular heterogeneity, or the ability of genetic clones to act and behave differently when exposed to the same set of environmental stimuli.

8 Nov 2004

Drugs News and Research

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Bretylium tosylate has unique benefits for patients with acute myocardial infarction

Obesity statistics are as bogus as weight-loss scams

Calcium channel blocker reduces adverse cardiovascular events

Stem cell gene linked to a portion of one of the most common childhood brain cancers

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease

New strain of mice to study nicotine addiction

Discovery of new gene that protects against lung cancer

FDA has warned consumers not to purchase or to consume Actra-Rx or Yilishen, promoted as "dietary supplements" for treating erectile dysfunction

Scientists have identified a fault in the brain waves of schizophrenics that may explain their hallucinations and disturbed thinking

Morton Grove Pharmaceuticals increases production of antiviral flu drug, Amantadine

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

ACE inhibitors not needed for many heart disease patients

Generic statin drugs shown to produce similar or better results than expensive brand-name drugs

Protease inhibitors used to treat HIV-1 infection may also be effective for treatment or prevention of malaria

Researchers have documented a novel form of resistance in leukemia cells to an anti-cancer drug

Researchers attempt to quantify processes underlying cell heterogeneity

In a world first, Australian researchers re-grow cut spinal cord

Drug reaction breakthrough

Major bone trial to test high dose corticosteroid steroid tablets

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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