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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

A third known case of HIV remission involving stem cell transplant documented

A woman with HIV who received a cord blood stem cell transplant to treat acute myeloid leukemia has had no detectable levels of HIV for 14 months despite cessation of antiretroviral therapy (ART), according to a presentation at today's Conference on Retroviruses and Opportunistic Infections (CROI).

15 Feb 2022

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

In a new study, a team of researchers demonstrated multiple site-directed mutagenesis as an efficient, easy, and more economically viable alternative to commercial gene synthesis to highlight how specific residues can contribute to the molecular structure and functioning of proteins.

15 Feb 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

U-M researchers measure out-of-pocket costs for follow-up tests after free cancer screening

With the White House putting cancer prevention and early treatment squarely in the sights of its renewed Cancer Moonshot initiative, recent University of Michigan research offers insights that policymakers could use to ensure more cancers are diagnosed earlier and reduce inequalities.

15 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Research highlights the need to include diverse populations in immunogenetic studies

Disease and health are the result of a complex interaction between humans and their pathogens. Genetic factors that partly determine host defenses sometimes differ significantly between people and populations.

14 Feb 2022

Study explores the gut microbiome of COVID-19 patients

Researchers investigated the changes in the gut microbiome and the presence of SARS-CoV-2 in stool samples of COVID-19 patients.

14 Feb 2022

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

A new study was based on the hypothesis that competitively inhibiting cellular furin and selectively targeting SARS-CoV-2 in the infected viral-producing cells is critical for therapeutic specificity.

14 Feb 2022

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

A new study provided the structural basis for a robust interaction between the receptor-binding domain of the SARS-CoV-2 Omicron spike protein and mouse ACE2.

13 Feb 2022

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

A Ludwig Cancer Research preclinical study has demonstrated that a common weight-loss diet could enhance the efficacy of chemotherapy for pancreatic cancer.

12 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

DNA News and Research

Further Reading

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

A third known case of HIV remission involving stem cell transplant documented

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

U-M researchers measure out-of-pocket costs for follow-up tests after free cancer screening

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Research highlights the need to include diverse populations in immunogenetic studies

Study explores the gut microbiome of COVID-19 patients

An alternative strategy targeting furin disrupts SARS-CoV-2 infection cycle

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

First unbiased proteome scale study expands the number of known transcriptional activators

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Epigenetic effects of pollutants may persist long enough to influence the evolutionary process

New rapid, cheaper test could help advance personalized cancer treatment

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

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