Immune System News and Research

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MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

13 Sep 2021

Analysis finds untapped potential for immunotherapy in older cancer patients

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

13 Sep 2021

Eosinophils play a role in the battle against cancer metastases, study finds

A new study at Tel Aviv University found that eosinophils - a type of white blood cells - are recruited to the battle against cancer metastases in the lungs.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

Functional impairment of HIV-specific T cells precedes aborted virus control

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

CD8+ T cells - known as "killer" T cells - are the assassins of the immune system. Once they are primed, they seek out and destroy other cells that are infected with virus or cells that are cancerous.

12 Sep 2021

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria.

12 Sep 2021

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

A clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer.

12 Sep 2021

NIH researchers develop a detailed cellular map of chronic MS lesions

Chronic lesions with inflamed rims, or "smoldering" plaques, in the brains of people with multiple sclerosis (MS) have been linked to more aggressive and disabling forms of the disease.

10 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Sequencing the human genome - a feat accomplished in 2003 - provided the list of ingredients that make up a human being, but not the instructions that explain how those ingredients are used by each cell type to create complex "meals."

9 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

Cellular program could turn T cells into effective cancer killers

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

9 Sep 2021

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

The gut microbiome - the collection of bacteria, viruses, fungi, and other microorganisms that reside in our gastrointestinal tracts - can impact us in a variety of different ways, from our metabolism to our mood.

9 Sep 2021

Understanding the changing coronavirus landscape

With the emergence of new SARS-CoV-2 variants such as beta and delta, people are not only getting a refresher course on the Greek alphabet but also experiencing confusion and anxiety about what the variants mean for public health.

9 Sep 2021

$New tool can rapidly quantify T cell fraction and predict immunotherapy response$

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies.

8 Sep 2021

People living with HIV have higher risk of sudden cardiac death, finds study

People living with human immunodeficiency virus (HIV) have a higher risk of sudden cardiac death than people who do not have HIV, especially if the virus is not well-controlled or if they have other heart disease risk factors.

8 Sep 2021

Immune System News and Research

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

Study finds possible direct connection between neurodegenerative diseases and the herpesvirus

Analysis finds untapped potential for immunotherapy in older cancer patients

Eosinophils play a role in the battle against cancer metastases, study finds

An oral COVID-19 vaccine induces mucosal and protective immunity

Functional impairment of HIV-specific T cells precedes aborted virus control

Researchers identify the spleen as primary site for priming of 'killer' T cells during influenza infection

Neutrophil extracellular traps boost the bacterial killing power of macrophages

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

NIH researchers develop a detailed cellular map of chronic MS lesions

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Physical exercise can improve cancer-induced anemia

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

Cellular program could turn T cells into effective cancer killers

Restoring beneficial gut microbes to enhance the efficacy of cancer immunotherapy

Understanding the changing coronavirus landscape

New tool can rapidly quantify T cell fraction and predict immunotherapy response

People living with HIV have higher risk of sudden cardiac death, finds study

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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