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New drug 'ubrogepant' may work for migraine

A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.

19 Nov 2019

Teenage binge drinking may lead to anxiety and alcohol abuse in later life

Exposure to high levels of alcohol in adolescence may shape adult behaviors, predisposing them to a higher risk of anxiety and alcohol abuse later in life, a new study found.

19 Nov 2019

MIT researchers develop method to isolate T cells primed for certain allergies or infections

When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder leap into action.

19 Nov 2019

Using 'Trojan horses' to kill tumor cells from within

Using "Trojan horses" to combat cancer from within the tumor cells themselves without damaging healthy tissues is the aim of this new tool created by researchers from the University of Granada, the Institute of Nanoscience of Aragon, the University of Zaragoza, and the Cancer Research UK Edinburgh Centre at the University of Edinburgh.

19 Nov 2019

25 years of research to fight cervical cancer

According to the World Health Organization, cervical cancer is the fourth most common type of cancer affecting women worldwide. Currently, early screenings of pre-cancerous tissues and vaccination have proven to be the most effective treatment strategies.

19 Nov 2019

Scientists develop new therapy for acute myeloid leukemia

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute, have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

19 Nov 2019

Antibiotics face an existential crisis

Antibiotics are facing an existential crisis less than a century after their introduction. The bacteria-fighting drugs are becoming less effective as a result of their overuse in both humans and animals.

18 Nov 2019

Vaping wrecks immune cell function, increases infection risk

A new study published in the Journal of the American College of Cardiology shows that e-cigarettes have toxic effects on neutrophils function, making them a threat to human health by increasing the likelihood of infection with Gram-negative bacteria.

17 Nov 2019

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Melbourne researchers have identified what makes a specialized immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

15 Nov 2019

Study uncovers how the molecule-sorting station in our cells is formed and maintained

The cells in our body are workshops that continuously operate to produce and process substances to keep us going. When a substance enters a cell for processing, it is surrounded by a portion of the cell's outer membrane to form a sac.

15 Nov 2019

WPI researchers developing miniaturized device to measure baby's blood oxygen levels

Researchers at Worcester Polytechnic Institute are developing a sensor the size of a Band-Aid that will measure a baby's blood oxygen levels, a vital indication of the lungs' effectiveness and whether the baby's tissue is receiving adequate oxygen supply.

14 Nov 2019

New treatment stops peanut allergy for 6 weeks with single dose

A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.

14 Nov 2019

Blocking a molecule could delay the progression of multiple sclerosis

Over 77,000 Canadians are living with multiple sclerosis, a disease whose causes still remain unknown. Presently, they have no hope for a cure.

14 Nov 2019

New technique enables the study of transporter proteins at a single-molecule level

Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans.

14 Nov 2019

'Smart toilets' may work as real-time method of monitoring health

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity - the humble toilet - may have potential to outperform them all.

13 Nov 2019

Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

White blood cells control final moments of their death

La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body.

12 Nov 2019

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

Researchers uncover new and unexploited drug target for childhood cancer

An Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be aimed at.

12 Nov 2019

Fluorescent carbon dots can effectively detect calcium levels in cells

In hospitals, doctors often advise patients to take calcium supplements. But does the calcium get into the cells that need it? Until recently, it's been hard to tell.

12 Nov 2019