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Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Lung cancer is the leading cause of cancer-related death worldwide. Improved understanding of driver mutations of non-small cell lung cancer (NSCLC) has led to more biomarker-directed treatment for patients with advanced stages.

26 Mar 2024

Machine learning identifies key cellular communities in soft tissue sarcoma

Using novel machine learning tools developed at Stanford Medicine, researchers have mapped three distinct cellular configurations that correspond to clinical outcomes for patients with a rare, difficult-to-treat cancer called soft tissue sarcoma.

26 Mar 2024

Hidden brain changes found to be common in people with a range of heart conditions

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

26 Mar 2024

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

Emergency department intervention aids in long-term smoking cessation

An opportunistic emergency department stop smoking prompt, comprising brief advice by a trained professional, an e-cigarette starter kit, and referral to local stop smoking services can help smokers quit, with a significant proportion of them still not smoking 6 months later, finds research published online in Emergency Medicine Journal.

26 Mar 2024

Breakthrough study offers hope for an effective HIV cure

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic.

26 Mar 2024

Viroclinics-DDL changes name to Cerba Research

Viroclinics-DDL a world-leading vaccine and antiviral specialty laboratory providing research and clinical trial solutions rooted in virology, proudly announces changing its name to Cerba Research as of the 1st of April 2024.

From Cerba Research 26 Mar 2024

Teva UK and Closed Loop Medicine announce strategic partnership to advance development of personalised medicines

Teva UK Limited and Closed Loop Medicine Ltd have announced a strategic partnership to advance the development of personalised medicine.

26 Mar 2024

GRADE study reveals key findings in diabetes medication efficacy

Diabetes affects more than 1 in 10 - or more than 38 million - Americans. People with diabetes who keep their blood sugar levels in the near-normal range generally have a much lower risk of developing diabetes complications such as heart, kidney, and eye diseases.

26 Mar 2024

Overdosing on chemo: A common gene test could save hundreds of lives each year

One January morning in 2021, Carol Rosen took a standard treatment for metastatic breast cancer. Three gruesome weeks later, she died in excruciating pain from the very drug meant to prolong her life.

26 Mar 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Molnupiravir influences SARS-CoV-2 evolution in immunocompromised patients

Study found that the antiviral molnupiravir affects the evolution of SARS-CoV-2 in immunocompromised patients, suggesting its use modifies viral mutation patterns and may impact viral evolution.

25 Mar 2024

Feedback loop involving estrogen linked to women's higher propensity to nicotine addiction

A newly discovered feedback loop involving estrogen may explain why women might become dependent on nicotine more quickly and with less nicotine exposure than men.

25 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

Statins show promise in reducing gum disease inflammation

Could taking statins benefit your mouth in addition to your arteries? A new study conducted in cell cultures showed that cholesterol-lowering drugs help to dampen the inflammation associated with periodontal disease by altering the behavior of macrophages, a type of immune cell.

25 Mar 2024

Review unveils the potential of Digital Guided Therapy in transforming endodontic treatments

Endodontic diseases present a significant challenge in dentistry due to their complex nature and the precision required in treatment. Traditionally, the success of these treatments has heavily relied on the dentist's skill and experience.

25 Mar 2024

A paramedic was skeptical about this Rx for stopping repeat opioid overdoses. Then he saw it help.

Fire Capt. Jesse Blaire steered his SUV through the mobile home park until he spotted the little beige house with white trim and radioed to let dispatchers know he'd arrived.

25 Mar 2024

After Appalachian hospitals merged into a monopoly, their ERs slowed to a crawl

In the small Appalachian city of Bristol, Virginia, City Council member Neal Osborne left a meeting on the morning of Jan. 3 and rushed himself to the hospital.

25 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Novel treatment approach to halt epilepsy progression identified

Only a very small percentage of neurons show changes after an epileptic seizure in mice, but these alterations can be permanent and trigger future seizures that can affect the whole brain and lead to impaired cognition, like memory and learning, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

22 Mar 2024

Therapy News and Research

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Machine learning identifies key cellular communities in soft tissue sarcoma

Hidden brain changes found to be common in people with a range of heart conditions

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Emergency department intervention aids in long-term smoking cessation

Breakthrough study offers hope for an effective HIV cure

Viroclinics-DDL changes name to Cerba Research

Teva UK and Closed Loop Medicine announce strategic partnership to advance development of personalised medicines

GRADE study reveals key findings in diabetes medication efficacy

Overdosing on chemo: A common gene test could save hundreds of lives each year

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Molnupiravir influences SARS-CoV-2 evolution in immunocompromised patients

Feedback loop involving estrogen linked to women's higher propensity to nicotine addiction

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Statins show promise in reducing gum disease inflammation

Review unveils the potential of Digital Guided Therapy in transforming endodontic treatments

A paramedic was skeptical about this Rx for stopping repeat opioid overdoses. Then he saw it help.

After Appalachian hospitals merged into a monopoly, their ERs slowed to a crawl

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Novel treatment approach to halt epilepsy progression identified

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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