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Alexion first quarter non-GAAP net income increases to $56.3 million

Alexion Pharmaceuticals, Inc. today announced financial results for the three months ended March 31, 2011. Alexion Pharmaceuticals, Inc. reported net product sales of Soliris® (eculizumab) of $166.1 million, reflecting steady additions of new patients, compared to $117.6 million for the same period in 2010.

21 Apr 2011

NIH funds Rice University study of new materials for growing replacement heart valves

A team of bioengineers from Rice University is bringing a promising new strategy for growing replacement heart valves closer to reality, thanks to a four-year, $1.2 million grant from the National Institutes of Health. The team hopes to use gel-like materials to generate three-dimensional patterns called scaffolds that can simultaneously mimic the complex structural and physical properties of heart-valve tissues and guide the behavior of tissue-forming cells.

21 Apr 2011

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

ARIAD Pharmaceuticals, Inc. today announced execution of three exclusive out-license agreements for separate aspects of its ARGENT™ cell-signaling regulation technology.

20 Apr 2011

Gen-Probe receives FDA marketing clearance for APTIMA Trichomonas vaginalis assay

Gen-Probe Incorporated announced today that the US Food and Drug Administration (FDA) has cleared for marketing its APTIMA® Trichomonas vaginalis assay on the fully automated TIGRIS® system.

20 Apr 2011

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

Two new studies highlight the power of sequencing cancer patients' genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer susceptibility mutations that can be passed from parent to child.

20 Apr 2011

LMP1 viral protein needs TRAF6 cellular protein to promote B cell activation signaling pathways: Study

By identifying a surprising association of two intracellular proteins, University of Iowa researchers have laid the groundwork for the development of new therapies to treat B cell lymphomas and autoimmune disease.

20 Apr 2011

New state of myosin in cardiac muscle with low ATP turnover rate could decrease metabolic load of myocardium

New insight into the physiology of cardiac muscle may lead to the development of therapeutic strategies that exploit an inherent protective state of the heart. The research, published by Cell Press online on April 19th in the Biophysical Journal, discovers a state of cardiac muscle that exhibits a low metabolic rate and may help to regulate energy use and promote efficiency in this hard-working and vital organ.

20 Apr 2011

Cord blood units treated with signaling molecule show favorable safety profile in long-term animal studies

An innovative experimental treatment for boosting the effectiveness of stem-cell transplants with umbilical cord blood has a favorable safety profile in long-term animal studies, report scientists from Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, and Children's Hospital Boston.

20 Apr 2011

First hand transplant in western United States

Ms Emily Fennell, a 26-year-old California woman became the first person in the western United States to receive a hand transplant.

19 Apr 2011

Single antibody injection limits tissue and organ destruction after ischaemic events

Medical researchers today held out promise that a simple injection is being developed to limit the devastating consequences of heart attacks and strokes.

19 Apr 2011

Journal of Clinical Oncology publishes CytRx tamibarotene Phase 2b trial results in APL

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced the publication of a case report in the peer-reviewed Journal of Clinical Oncology documenting the use of tamibarotene in the successful treatment of a patient with recurrent advanced-stage acute promyelocytic leukemia.

19 Apr 2011

New guidelines for cardiac specialists

A series of new guidelines for cardiac specialists has been developed to determine when heart failure patients should receive a mechanical heart-pumping device.

18 Apr 2011

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

New results from the largest multicenter clinical trial for heart transplant patients will be released this week at the International Society for Heart & Lung Transplantation 31st Annual Meeting and Scientific Sessions in San Diego. Results show clinical benefit for the use of Everolimus in heart transplant patients.

16 Apr 2011

Roundup: Medicaid bill headed for Florida Senate floor; Texas nursing home funding vulnerable in state budget

The Texas Legislature is faced with a budget challenge that has pitted the Republican majority's desire to cut government spending against a vulnerable target: nursing homes.

16 Apr 2011

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Pfizer Inc. announced today top-line results from the ORAL Scan Phase 3 study of tofacitinib, formerly known as tasocitinib, an investigational, novel, oral JAK inhibitor.

15 Apr 2011

Patients with heart failure can benefit from left ventricular assist device

Non-cardiac surgery can be performed safely in patients with a heart device typically implanted into patients waiting for a transplant, according to a study at Henry Ford Hospital in Detroit.

15 Apr 2011

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.

15 Apr 2011

Genzyme reports positive data from 5-year alemtuzumab Phase 2 study in MS

Genzyme Corp., a subsidiary of sanofi-aventis Group, today reported additional five-year patient data from its completed Phase 2 multiple sclerosis (MS) trial showing that nearly two-thirds of alemtuzumab treated patients remained free of clinically-active disease as much as four years after most patients received their last course of the investigational drug.

15 Apr 2011

Donor-specific antibodies may accelerate arteriosclerosis after kidney transplantation

Kidney transplant recipients who develop antibodies in response to receiving new organs can develop accelerated arteriosclerosis, or narrowing of the arteries that supply blood to the kidney, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results indicate that arteriosclerosis resulting from such donor-specific antibodies may play an important role in organ rejection following transplantation.

15 Apr 2011

Sea squirt study may help solve organ rejection problems in humans

Studies of the small sea squirt may ultimately help solve the problem of rejection of organ and bone marrow transplants in humans, according to scientists at UC Santa Barbara.

15 Apr 2011

Transplant News and Research

Alexion first quarter non-GAAP net income increases to $56.3 million

NIH funds Rice University study of new materials for growing replacement heart valves

ARIAD executes three exclusive out-license agreements for ARGENT cell-signaling regulation technology

Gen-Probe receives FDA marketing clearance for APTIMA Trichomonas vaginalis assay

Sequencing the genomes of cancer patients help doctors decide the best course of treatment

LMP1 viral protein needs TRAF6 cellular protein to promote B cell activation signaling pathways: Study

New state of myosin in cardiac muscle with low ATP turnover rate could decrease metabolic load of myocardium

Cord blood units treated with signaling molecule show favorable safety profile in long-term animal studies

First hand transplant in western United States

Single antibody injection limits tissue and organ destruction after ischaemic events

Journal of Clinical Oncology publishes CytRx tamibarotene Phase 2b trial results in APL

New guidelines for cardiac specialists

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

Roundup: Medicaid bill headed for Florida Senate floor; Texas nursing home funding vulnerable in state budget

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Patients with heart failure can benefit from left ventricular assist device

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

Genzyme reports positive data from 5-year alemtuzumab Phase 2 study in MS

Donor-specific antibodies may accelerate arteriosclerosis after kidney transplantation

Sea squirt study may help solve organ rejection problems in humans

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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