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Transcriptional reprogramming of monocytes in COVID-19

In a recent study posted to the bioRxiv* server, researchers examined the functionality of cluster of differentiation 14-positive (CD14+) monocytes in patients with mild or moderate coronavirus disease 2019 (COVID-19).

7 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

IQWiG highlights weak evidence on the use of two innovative high-risk medical devices

When assessing new examination and treatment methods involving high-risk medical devices in accordance with §137h of the German Social Code, Book V (SGB V), the Institute for Quality and Efficiency in Health Care (IQWiG) examines the data submitted by the hospital and the manufacturer.

6 Apr 2022

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

For patients with cancer, the tumor-killing power of chemotherapeutic drugs is a double-edged sword. While many cancer drugs kill tumor cells, they can also harm healthy cells as they travel throughout the bloodstream.

6 Apr 2022

SEACells: an algorithm for identifying metacells

A new study has presented single-cell aggregation of cell-states (SEACells), a graph-based algorithm for identifying metacells.

6 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Higher cereal fiber intake associated with lower inflammation

A new study assesses the association between dietary fiber intake with inflammatory markers associated with cardiovascular disease.

4 Apr 2022

Exercise prior to tumor bearing may help reduce the effects of wasting syndrome

A new study has identified yet another benefit of keeping up your exercise routine. In experiments performed with mice, researchers found that exercising prior to developing cancer was associated with slower tumor growth and helped reduce the effects of a cancer complication known as wasting syndrome, or cachexia.

4 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin - a natural compound found in the spice cardamom and other plants - could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

Multi-mineral supplement could help reduce downstream consequences of fatty liver disease

Results from a preclinical study add new evidence that a multi-mineral dietary supplement known as Aquamin could be a simple and effective way to reduce the long-term health consequences of non-alcoholic fatty liver disease.

3 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

An analysis by Yale Cancer Center researchers identified accelerated genetic aging in breast tissue adjacent to breast cancer tumors.

31 Mar 2022

Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome

Researchers developed 1,2-dimpalmiyristoyl-sn-glycero-3-phosphocholine liposomes co-loaded with methylprednisolone and N-acetyl cysteine to treat acute respiratory distress syndrome in vivo.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

The subventricular neurogenic niche is a region of the brain where tumor cells can hide from chemotherapy treatment to reappear later, causing relapses in patients with childhood acute lymphoblastic leukemia (ALL), and preventing the formation of new neurons, as demonstrated by research led by Universidad Complutense de Madrid (UCM).

30 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots contain isoflavonoids with high antioxidant and cytotoxic activity, scientists have discovered.

30 Mar 2022

Tumor News and Research

Transcriptional reprogramming of monocytes in COVID-19

Researchers discover over 40 new genetic markers for Alzheimer’s disease

IQWiG highlights weak evidence on the use of two innovative high-risk medical devices

Researchers develop novel device to “cleanse” the blood of chemotherapeutic drugs

SEACells: an algorithm for identifying metacells

Phenotypic changes in monocytes from COVID-19 patients

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Higher cereal fiber intake associated with lower inflammation

Exercise prior to tumor bearing may help reduce the effects of wasting syndrome

Researchers use breast milk to identify new set of protein biomarkers for cancer

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Multi-mineral supplement could help reduce downstream consequences of fatty liver disease

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Yale researchers identify accelerated genetic aging in breast tissue adjacent to tumors

Liposomes tailored for pulmonary delivery for treating acute respiratory distress syndrome

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Soy molasses and kudzu roots may help fight against pediatric tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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