Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists describes new advantageous way to detect different immune cells in the blood

When a person becomes sick or is exposed to an unwelcome substance, the body mobilizes specific proportions of different immune cells in the blood. Methods of discovering and detecting those profiles are therefore useful both clinically and in research. In a new paper in the journal Genome Biology, a team of scientists describes a new and uniquely advantageous way to detect them.

6 Mar 2014

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

In a new study that could help doctors extend the lives of patients awaiting liver transplants, a Rice University-led team of researchers examined the metabolic breakdown that takes place in liver cells during late-stage cirrhosis and found clues that suggest new treatments to delay liver failure.

5 Mar 2014

Microgravity may suppress tumors, study reveals

In space, things don't always behave the way we expect them to. In the case of cancer, researchers have found that this is a good thing: some tumors seem to be much less aggressive in the microgravity environment of space compared to their behavior on Earth. This observation, reported in research published in February by the FASEB Journal, could help scientists understand the mechanism involved and develop drugs targeting tumors that don't respond to current treatments. This work is the latest in a large body of evidence on how space exploration benefits those of us on Earth.

4 Mar 2014

Biostatistics provides clues to understanding autism: an interview with Dr Knut M. Wittkowski, The Rockefeller University

The incidence of autism spectrum disorders has increased sharply since it was first described 60 years ago. Today, ASD affects more than 1% of all children in the U.S. and about half of them develop a life-long disability.

3 Mar 2014

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Neuroblastoma is one of the most common and lethal types of childhood cancers. In a paper published online today in OncoTarget, a researcher at the University of Texas Health Science Center at San Antonio unveils the important role of microRNAs in regulating neuroblastoma development, pointing to new therapeutic possibilities.

3 Mar 2014

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

A protein that controls the metamorphosis of the common fruit fly could someday play a role in reversing brain injuries, said Duke University researchers.

28 Feb 2014

Study provides novel insight into the impact of genes on Huntington's disease

A study led by researchers at Boston University School of Medicine provides novel insight into the impact that genes may have on Huntington's disease (HD). The study, published online in PLOS Genetics, identified specific small segments of RNA (called micro RNA or miRNA) encoded in DNA in the human genome that are highly expressed in HD.

27 Feb 2014

Study identifies enzyme with key role in precancerous lesions

Cancer of the pancreas is usually not detected until it's too late to cure. But precursor lesions that form in the pancreas and its ducts can signal the disease before it strikes, and when caught early enough, they can be prevented from progressing to become cancer.

26 Feb 2014

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

After an extensive review by a panel of top cancer experts, the National Cancer Institute (NCI) rated The Wistar Institute Cancer Center as "exceptional" and recommended renewal for Wistar's Support Grant with an award of $14.9 million over the next five years.

24 Feb 2014

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

Certain fragments of DNA shed by tumors into the bloodstream can potentially be used to non-invasively screen for early-stage cancers, monitor responses to treatment and help explain why some cancers are resistant to therapies, according to results of an international study led by Johns Hopkins Kimmel Cancer Center investigators.

20 Feb 2014

Genetic profiles obtained from nasal passages guide individualized therapy, research

It has become increasingly clear in recent years that asthma comes in several variations, with different causes, different pathologies and different responses to therapy.

20 Feb 2014

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

A new UCLA-led study shows that a blood test commonly used to determine whether heart transplant recipients are rejecting their new organ can also predict potential rejection-related problems in the future.

19 Feb 2014

Scientists develop mathematical method for classifying forms of glioblastoma

Scientists at The Wistar Institute have developed a mathematical method for classifying forms of glioblastoma, an aggressive and deadly type of brain cancer, through variations in the way these tumor cells "read" genes. Their system was capable of predicting the subclasses of glioblastoma tumors with 92 percent accuracy. With further testing, this system could enable physicians to accurately predict which forms of therapy would benefit their patients the most.

18 Feb 2014

Samoa Island harbors a global health mystery that could predict obesity crisis

The South Pacific archipelago of Samoa and American Samoa harbors a global health mystery that may seem both remote and extreme but could foretell trends in obesity and related conditions across much of the developing world.

18 Feb 2014

Study describes new, cost-effective method for screening chemicals for potential environmental impact

Every year waste treatment facilities in the United States process more than eight million tons of semi-solid sewage called biosolids -- about half of which is recycled into fertilizer and spread on crop land.

17 Feb 2014

Extreme loneliness can increase premature death by 14% in older adults

Feeling extreme loneliness can increase an older person's chances of premature death by 14 percent, according to research by John Cacioppo, professor of psychology at the University of Chicago.

17 Feb 2014

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

The elusive progenitor cells that give rise to innate lymphoid cells-a recently discovered group of infection-fighting white blood cells-have been identified in fetal liver and adult bone marrow of mice, researchers from the University of Chicago report early online in the journal Nature.

14 Feb 2014

Researchers develop new model for isolating effects of nutrients on gene expression, physiology

Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression and physiology.

14 Feb 2014

Scientists take steps to identify genetic component to bipolar disorder

Scientists know there is a strong genetic component to bipolar disorder, but they have had an extremely difficult time identifying the genes that cause it. So, in an effort to better understand the illness's genetic causes, researchers at UCLA tried a new approach.

13 Feb 2014

Researchers examine how evolution relates to health

February 12 marks the birth of the 19th century naturalist Charles Darwin, who launched the scientific study of evolution. While Darwin's theory laid the groundwork, ongoing studies have deepened our understanding of evolution, including how it relates to health. Research funded by the National Institutes of Health has helped answer many questions about evolution, health and medicine. Here's a sampling.

12 Feb 2014

Gene Expression News and Research

Further Reading

Scientists describes new advantageous way to detect different immune cells in the blood

Metabolic profiling of liver cells suggests new treatments for cirrhosis patients

Microgravity may suppress tumors, study reveals

Biostatistics provides clues to understanding autism: an interview with Dr Knut M. Wittkowski, The Rockefeller University

Scientists unveil role of microRNAs in regulating neuroblastoma, pointing to new therapeutic possibilities

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

Study provides novel insight into the impact of genes on Huntington's disease

Study identifies enzyme with key role in precancerous lesions

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

Certain fragments of DNA shed by tumors can be used to non-invasively screen for early-stage cancers

Genetic profiles obtained from nasal passages guide individualized therapy, research

AlloMap test can be used to assess risk of dysfunction or rejection of a transplanted heart

Scientists develop mathematical method for classifying forms of glioblastoma

Samoa Island harbors a global health mystery that could predict obesity crisis

Study describes new, cost-effective method for screening chemicals for potential environmental impact

Extreme loneliness can increase premature death by 14% in older adults

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

Researchers develop new model for isolating effects of nutrients on gene expression, physiology

Scientists take steps to identify genetic component to bipolar disorder

Researchers examine how evolution relates to health

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