Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

UK acid-related disease trends revealed

The incidence of Barrett’s esophagus in the UK has doubled in recent years, but the incidence of gastroesophageal reflux disease is stable, study findings reveal.

11 Oct 2012

No benefit from irrigation during appendectomy

Irrigating the peritoneal cavity during appendectomy for perforated appendicitis offers no advantage over suction alone, with similar rates of postoperative abscess in children treated using both approaches, according to the findings of a US study.

11 Oct 2012

Zero out of TEN for fecal incontinence treatment

Transcutaneous electrical nerve stimulation is no more effective than placebo for the treatment of fecal incontinence, say French researchers.

10 Oct 2012

Dieting, exercise can spur HDL cholesterol production in type 2 diabetics

With a little exercise and dieting, overweight people with type 2 diabetes can still train their fat cells to produce a hormone believed to spur HDL cholesterol production, report medical researchers from The Methodist Hospital and eight other institutions in an upcoming issue of the Journal of Lipid Research.

10 Oct 2012

Researchers identify two new small 'chaperone' molecules that may treat Schindler/Kanzaki disease

University of Massachusetts Amherst researchers, experts in revealing molecular structure by X-ray crystallography, have identified two new small "chaperone" molecules that may be useful in treating the inherited metabolic disorder known as Schindler/Kanzaki disease.

10 Oct 2012

Modifying factors may be responsible for non-diabetic kidney disease in African-Americans

The high rate of non-diabetic kidney disease in African-Americans is strongly associated with variations in a particular gene. Yet, not everyone who inherits these variations develops the disease.

10 Oct 2012

Chronic kidney disease changes the composition of intestinal bacterial microbes

Chronic kidney disease changes the composition of intestinal bacterial microbes that normally play a crucial role in staving off disease-causing pathogens and maintaining micronutrient balance, according to UC Irvine researchers.

10 Oct 2012

Two novel GFR equations predict kidney function in elderly

Researchers report that two “new” equations may accurately measure kidney function in elderly individuals with nonsevere kidney disease.

9 Oct 2012

Early communication strategies improve end of liver transplant patients’ lives

A multidisciplinary communication intervention involving physicians and family members of liver transplant patients treated in surgical intensive care units can improve end-of-life care, show study results.

9 Oct 2012

New time-resolved multi-frame MRI technique can identify early-stage CAD

With the results of a magnetic resonance imaging (MRI) study from the National Institutes of Health (NIH), researchers say they are closer to finding an imaging technique that can identify thickening of the coronary artery wall, an early stage of coronary heart disease (CAD). The study is published online in the journal Radiology.

9 Oct 2012

Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients

Trevena, Inc., the leader in the discovery and development of G-protein coupled receptor (GPCR) biased ligands, today announced that it has successfully completed a Phase 2a study on the hemodynamic effects of TRV027 in patients with advanced heart failure with reduced ejection fraction.

8 Oct 2012

FMCNA urges dialysis patients to get flu shots

With flu season just around the corner, Fresenius Medical Care North America (FMCNA), the nation's leading network of dialysis facilities, is urging dialysis patients to get flu shots to protect themselves against this common infectious disease. In October, FMCNA will begin offering at no cost to all of its dialysis patients and staff, flu vaccinations, which protect against both seasonal flu and H1N1 swine flu.

6 Oct 2012

Oral medication as effective as Botox injections for treating incontinence in women

Oral medication for treating a type of incontinence in women is roughly as effective as Botox injections to the bladder, reported researchers who conducted a National Institutes of Health clinical trials network study, with each form of treatment having benefits and limitations.

6 Oct 2012

Two genes linked to increased risk of diabetes-associated kidney disease

An international group of researchers has discovered two genes that increase the risk of developing diabetes-associated kidney disease.

6 Oct 2012

Home hemodialysis more accessible than ever

Most patients with chronic kidney disease who undergo hemodialysis put up with a grueling treatment regimen that involves going into a clinic several days a week and sitting through a three-to-four hour dialysis session at each visit. Home hemodialysis is more accessible than ever, though, with the advent of newer systems that are easier for patients to learn, use, and maintain, according to a review appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

5 Oct 2012