Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Study finds no clinical advantage of budesonide inhaler over fluticasone in COPD

A study compares budesonide-glycopyrrolate-formoterol and fluticasone-umeclidinium-vilanterol, revealing insights on COPD exacerbations and pneumonia risk.

6 Jan 2025

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

Key risk factors influencing mortality rates in chronic pulmonary aspergillosis patients

A systematic review reveals chronic pulmonary aspergillosis mortality is driven by age and underlying conditions, highlighting the need for targeted therapies.

3 Dec 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

New study confirms: Anti-inflammatory inhalers reduce severe asthma complications

This study highlights the benefits of anti-inflammatory inhalers in asthma management, showing reduced complications and modest improvements in symptom control.

30 Oct 2024

Genetic variant identified as potential predictor for severe ulcerative colitis

The HLA-DRB1*01:03 genetic variant is associated with severe ulcerative colitis, significantly raising the risk of major surgeries and hospitalizations.

21 Oct 2024

Research links COVID-19 vaccines to temporary facial palsy in over 5,000 patients

This research identifies a potential link between COVID-19 vaccines and facial palsy, calling for enhanced surveillance and understanding of vaccine safety.

15 Oct 2024

Machine learning early warning system reduces non-palliative deaths in general medicine unit

A study on CHARTwatch reveals its effectiveness in predicting patient deterioration, leading to reduced non-palliative care mortality in general medicine units.

18 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Molnupiravir reduces long-term COVID-19 symptoms but shows limited impact on hospitalizations

Molnupiravir treatment for COVID-19 shows modest long-term benefits, reducing symptoms and improving well-being at three and six months. However, the differences were small, with no impact on hospitalization rates.

11 Sep 2024

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Research shows elevated metformin in diabetic foot ulcer exudates when combined with insulin, highlighting potential for improved wound healing therapies.

9 Sep 2024

Study suggests limiting oral corticosteroid use to 90 days reduces adverse effects in atopic dermatitis patients

Researchers evaluated the association between long-term oral corticosteroid use and adverse events in adult patients with atopic dermatitis.

24 Jul 2024

Vitamin D for carpal tunnel syndrome symptoms

Study examines the impact of vitamin D supplementation on carpal tunnel syndrome (CTS) patients with low vitamin D levels, finding that it improves pain relief and symptom severity when added to corticosteroid therapy.

23 Jun 2024

Tips to help keep feet healthy during summer and prevent athlete’s foot

As the days heat up and we head into the Summer, many of us suddenly seem to remember that the appendages at the end of our legs need some love and care too.

22 Jun 2024

New insights into predictors of organ damage in childhood-onset SLE

Childhood-onset systemic lupus erythematosus (cSLE) is a chronic, severe autoimmune disorder that carries a risk of early organ damage.

14 Jun 2024

Crinecerfont: A promising compound for reducing corticosteroid dependence in CAH patients

People born with the common form of congenital adrenal hyperplasia lack an enzyme in the adrenal glands needed to make the hormones cortisol and aldorsterone, which are involved in the body's response to stress and blood pressure regulation.

10 Jun 2024

Study reveals low adoption of recommended smart inhaler therapy for asthma

Only 14.5 percent of adult patients with moderate or severe asthma are prescribed the recommended SMART combination inhaler regimen and over 40 percent of academic pulmonary and allergy clinicians have not adopted this optimal therapy, according to research published at the ATS 2024 International Conference.

21 May 2024

Empowering asthma patients through education

On World Asthma Day 2024 the message is clear: "Asthma Education Empowers." The Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, stresses the crucial role of education in empowering people with asthma to manage their condition effectively and to know when to seek medical assistance.

7 May 2024

Gut microbiome shows no clear link to cognitive impairments in Parkinson's disease

Study investigates the gut microbiome's role in Parkinson's disease patients with mild cognitive impairments, revealing no distinct microbiome signatures associated with MCI in PD compared to cognitively normal PD patients or controls.

8 Apr 2024