Corticosteroid News and Research

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Corticosteroids are any steroid hormones made in the adrenal cortex (the outer part of the adrenal gland). They are also made in the laboratory. Corticosteroids have many different effects in the body, and are used to treat many different conditions. They may be used as hormone replacement, to suppress the immune system, and to treat some side effects of cancer and its treatment. Corticosteroids are also used to treat certain lymphomas and lymphoid leukemias.

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

A new study of more than 2,900 patients provides evidence that it's likely best to use as little corticosteroid medicine as possible when treating people who have lupus pericarditis, a common heart complication of the autoimmune disease Systemic Lupus Erythematosus (SLE).

26 Feb 2025

Epidural steroid injections may offer modest short-term pain relief for some back pain

The American Academy of Neurology (AAN) has developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for people with certain kinds of chronic back pain.

13 Feb 2025

Asthma and antibiotic use increase the likelihood of revision sinus surgery

The probability of revision sinus surgery including the removal of nasal polyps is higher if the patient has asthma or is on antibiotics at the time of their initial surgery. However, higher age was not a predictor of revision surgery, according to a new study.

4 Feb 2025

AGA releases updated guidelines on hepatitis B reactivation in patients on immunosuppressive drugs

The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline in Gastroenterology addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.

23 Jan 2025

Online resource launched to empower people with vulval lichen sclerosus

A new online guide has launched to support and empower people with vulval lichen sclerosus (LS) to learn about the condition, access the right treatment and live more comfortably.

21 Jan 2025

Researchers uncover diverse asthma endotypes in youths using nasal transcriptomics

The study highlights T2-low and T17-high asthma endotypes in minoritized youths, offering insights for precision medicine and improved asthma management.

7 Jan 2025

Study finds no clinical advantage of budesonide inhaler over fluticasone in COPD

A study compares budesonide-glycopyrrolate-formoterol and fluticasone-umeclidinium-vilanterol, revealing insights on COPD exacerbations and pneumonia risk.

6 Jan 2025

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

Key risk factors influencing mortality rates in chronic pulmonary aspergillosis patients

A systematic review reveals chronic pulmonary aspergillosis mortality is driven by age and underlying conditions, highlighting the need for targeted therapies.

3 Dec 2024

Diabetes drugs cut asthma attacks by up to 70%, reshaping treatment options

Metformin and GLP-1 receptor agonists significantly reduce asthma attacks in patients with type 2 diabetes, offering potential new treatments for asthma.

19 Nov 2024

New study links circadian gene variants to winter depression

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like behaviors in humanized mice models.

13 Nov 2024

New study confirms: Anti-inflammatory inhalers reduce severe asthma complications

This study highlights the benefits of anti-inflammatory inhalers in asthma management, showing reduced complications and modest improvements in symptom control.

30 Oct 2024

Genetic variant identified as potential predictor for severe ulcerative colitis

The HLA-DRB1*01:03 genetic variant is associated with severe ulcerative colitis, significantly raising the risk of major surgeries and hospitalizations.

21 Oct 2024

Research links COVID-19 vaccines to temporary facial palsy in over 5,000 patients

This research identifies a potential link between COVID-19 vaccines and facial palsy, calling for enhanced surveillance and understanding of vaccine safety.

15 Oct 2024

Machine learning early warning system reduces non-palliative deaths in general medicine unit

A study on CHARTwatch reveals its effectiveness in predicting patient deterioration, leading to reduced non-palliative care mortality in general medicine units.

18 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Molnupiravir reduces long-term COVID-19 symptoms but shows limited impact on hospitalizations

Molnupiravir treatment for COVID-19 shows modest long-term benefits, reducing symptoms and improving well-being at three and six months. However, the differences were small, with no impact on hospitalization rates.

11 Sep 2024

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Research shows elevated metformin in diabetic foot ulcer exudates when combined with insulin, highlighting potential for improved wound healing therapies.

9 Sep 2024

Study suggests limiting oral corticosteroid use to 90 days reduces adverse effects in atopic dermatitis patients

Researchers evaluated the association between long-term oral corticosteroid use and adverse events in adult patients with atopic dermatitis.

24 Jul 2024

Vitamin D for carpal tunnel syndrome symptoms

Study examines the impact of vitamin D supplementation on carpal tunnel syndrome (CTS) patients with low vitamin D levels, finding that it improves pain relief and symptom severity when added to corticosteroid therapy.

23 Jun 2024